KEGG   Bos mutus (wild yak): 102276357
Entry
102276357         CDS       T02919                                 
Symbol
GART
Name
(RefSeq) phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
  KO
K11787  phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1]
Organism
bom  Bos mutus (wild yak)
Pathway
bom00230  Purine metabolism
bom00670  One carbon pool by folate
bom01100  Metabolic pathways
bom01523  Antifolate resistance
Module
bom_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:bom00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    102276357 (GART)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    102276357 (GART)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    102276357 (GART)
Enzymes [BR:bom01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.2  phosphoribosylglycinamide formyltransferase 1
     102276357 (GART)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.3  Cyclo-ligases
    6.3.3.1  phosphoribosylformylglycinamidine cyclo-ligase
     102276357 (GART)
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.13  phosphoribosylamine---glycine ligase
     102276357 (GART)
SSDB
Motif
Pfam: GARS_A Formyl_trans_N AIRS_C GARS_N GARS_C AIRS ATP-grasp ATP-grasp_3 ATP-grasp_2 CPSase_L_D2 Dala_Dala_lig_C ATP-grasp_4 RimK
Other DBs
NCBI-GeneID: 102276357
NCBI-ProteinID: XP_005893411
UniProt: A0A6B0RPC0
Position
Un
AA seq 1010 aa
MAARVLVIGNGGREHTLAWKLAQSTHVKQVLVTPGNAGTACSEKISNTDISISDHTALAQ
FCKDEKIEFVVVGPEAPLAAGIVGNLNSVGVRCFGPTAQAAQLESSKRFAKEFMDRHGIS
TARWRAFTKPKEACDFIMSADFPALVVKASGLAAGKGVIVARSKEEACEAVREIMQGKAF
GEAGETVVIEELLEGEEVSCLCFTDGRTVAPMPPAQDHKRLLEGDEGPNTGGMGAYCPAP
QVSKDLLLKIKNNILQRTVDGMQEEGMPYTGVLYAGIMLTKNGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSILDGLLCTSLPVWLDNCAAVTVVMASKGYPGDYTKGVEITGFPEA
QALGLEVFQAGTALKDGKVVTNGGRVLTVTAIRENLISALEEARKGLAAIKFEGAVYRKD
IGFRAIAFLQQPRGLTYKESGVDIAAGNTLVQKIKPLAKATSRPGCDVDLGGFAGLFDLK
AAGFTDPLLACGTDGVGTKLKIAQQCSKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLRTTEAVITGIAKACKKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
QLERITEGDAVIGIASSGLHSNGFSLVRKIVAKSSLEYSSPAPGGCGDQTLGDLLLTPTK
IYSRSLLPVLRSGRVKAVAHITGGGLLENIPRVLPQKLGVNLDAQTWRVPRIFSWLQQEG
HLSEEEMARTFNCGIGAALVVSEDLVKQTLQDIEQHQEEACVIGRVVACPEGSPRVKVEH
LIETMQINGSVLENGTLRNHFSVQPKKARVAVLISGTGSNLQALIDSTREPSSLAHIVIV
ISNKAAVAGLDKAEKAGIPTRVINHKLYKNRAAFDTAIDEVLEEFSTDIVCLAGFMRILS
GPFVRKWNGKMLNIHPSLLPSFKGSNAHEQVLDAGVTVTGCTVHFVAEDVDAGQIILQEA
VPVKRGDTVETLSERVKLAEHKIFPSALQLVASGAVRLGENGRICWVTED
NT seq 3033 nt   +upstreamnt  +downstreamnt
atggcagcccgagtacttgtcattggcaatggaggacgagaacacacgctggcctggaaa
cttgcacagtctactcatgtcaaacaagtgttggttaccccaggaaatgcaggcactgcc
tgctctgagaagatttcaaatactgacatctcaatcagtgatcatactgcccttgcgcag
ttctgcaaagatgagaaaattgaattcgtagttgttggaccagaggcacctctagctgct
ggaattgttgggaacctgaactctgtgggagttcggtgctttggccccacagcacaagca
gctcagttagagtccagcaagagatttgccaaagagtttatggaccgacatggaatctca
actgcaagatggagagctttcactaaacctaaagaagcctgtgacttcattatgagtgca
gacttccctgctttggttgtgaaggccagtggtcttgcagctgggaaaggggtaattgtt
gccaggagcaaagaggaggcctgtgaagctgtcagagagattatgcagggtaaagctttc
ggagaagcaggagaaacagttgtcattgaagaacttcttgaaggagaagaggtgtcttgt
ctgtgcttcactgatggacggactgtggcccccatgcccccagcacaggaccataagcga
ttgctggagggcgatgagggccccaacacgggaggaatgggagcctattgtccagcccct
caggtttctaaggatttgttgctaaaaattaaaaataatattcttcagaggacagtggat
ggcatgcaggaggagggtatgccatacacaggtgtcctctatgctggtataatgctgacc
aagaacggccccaaagttctggaatttaattgccgtttcggtgatccagagtgccaagtg
atcctcccacttcttaaaagtgatctttatgaagtgattcagtctatcttagatggcttg
ctctgcacttctctgcctgtttggctggacaactgtgctgccgtaactgtggtcatggca
agtaaaggttatccgggagactacaccaagggtgtagagataacagggtttcctgaggct
caggctttaggactggaggtgttccaagcaggcactgccctaaaagatggcaaggtggtg
actaacgggggcagggtccttactgtcacggccatcagggaaaatctcatctcagctctt
gaagaagccaggaaaggacttgccgccataaagtttgagggagctgtttataggaaagac
atcggctttcgagccatagctttcctccagcagcccaggggcctgacttacaaggaatct
ggggtagacattgcagctggtaatacgctggtccagaaaattaaacctttagcgaaggcc
acctccagaccaggctgtgatgttgatcttggaggttttgctggtctttttgatttgaaa
gcagctggtttcactgatcctcttctggcttgtggaacagatggcgttgggacgaaactg
aagattgcccagcagtgcagtaaacatgacaccattggtcaggatttggttgcgatgtgt
gtaaatgacattctggcacaaggagcagagcccctctttttcctcgattacttttcctgt
ggaaaacttgacctccgtactactgaagctgttatcactgggatcgccaaagcttgtaaa
aaggctggatgtgctctcctcggaggtgaaacggcagagatgcctgacatgtaccctcct
ggagaatatgatctagctggttttgccgttggtgccatggagcgggatcagaaacttcct
caactggaaagaatcacggaaggagacgctgttattggaatcgcttcatctggtcttcac
agcaacggattcagccttgtgaggaaaattgtagcaaaatcttctctcgagtactcttct
ccagcacctggtggctgtggtgaccagaccttaggtgacttacttctaaccccaaccaaa
atctacagccgctcactgttacctgtcctgcgttcaggacgtgttaaggccgttgcacat
attactggtggaggattactggaaaacatccccagagtcctccctcagaaattgggggtg
aatttagatgcccagacctggagggtccccaggatcttctcatggttacagcaggaaggc
cacctctctgaagaggagatggccagaacatttaactgtgggattggggctgccctcgtg
gtatcagaggacctggtgaagcagactctgcaggatattgagcagcaccaggaagaagcc
tgcgtgatcggcagagtggttgcatgtcccgagggttctcctcgtgtgaaagtcgagcat
ctgattgaaaccatgcaaataaatggatcagtattggagaatggaaccctgagaaatcat
ttctctgttcaaccaaaaaaggcaagagtagctgtcttaatttctgggacaggatcgaac
ctccaagctctcatagacagcactagggagccaagtagcttggcacacattgtcattgtg
atctccaacaaagctgcagtggctggcttagataaagcagaaaaagccgggattcccacg
agagtaattaatcataaattatataaaaatcgtgcagcatttgacactgcaattgacgaa
gtccttgaagagttctccacagacatagtctgtcttgcaggattcatgagaattttgtct
ggccccttcgtcagaaaatggaatgggaaaatgctcaatatccacccatccttgctccct
tcgtttaagggttcaaatgcccatgaacaagtcctggacgctggggtcacagtcaccggg
tgcaccgtgcactttgtagctgaagatgtagatgccggtcaaattatcttacaggaagcc
gttccagtgaagaggggtgacactgttgaaactctatctgagagagtaaaattagcagaa
cataaaatatttccctcagccctccagctggtggccagtggagctgtacggcttggagaa
aatggcagaatctgttgggtcacagaggactga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (13)   
   KEGG COMPOUND (13)   
Chemical reaction (7)   
   KEGG ENZYME (3)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (13)   
   Pfam (13)   
All databases (48)   

Download RDF
DBGET integrated database retrieval system