KEGG   Bos mutus (wild yak): 102278724
Entry
102278724         CDS       T02919                                 
Symbol
PRKCA
Name
(RefSeq) protein kinase C alpha
  KO
K02677  classical protein kinase C alpha type [EC:2.7.11.13]
Organism
bom  Bos mutus (wild yak)
Pathway
bom01521  EGFR tyrosine kinase inhibitor resistance
bom04010  MAPK signaling pathway
bom04012  ErbB signaling pathway
bom04014  Ras signaling pathway
bom04015  Rap1 signaling pathway
bom04020  Calcium signaling pathway
bom04066  HIF-1 signaling pathway
bom04070  Phosphatidylinositol signaling system
bom04071  Sphingolipid signaling pathway
bom04072  Phospholipase D signaling pathway
bom04150  mTOR signaling pathway
bom04151  PI3K-Akt signaling pathway
bom04261  Adrenergic signaling in cardiomyocytes
bom04270  Vascular smooth muscle contraction
bom04310  Wnt signaling pathway
bom04360  Axon guidance
bom04370  VEGF signaling pathway
bom04510  Focal adhesion
bom04540  Gap junction
bom04613  Neutrophil extracellular trap formation
bom04650  Natural killer cell mediated cytotoxicity
bom04664  Fc epsilon RI signaling pathway
bom04666  Fc gamma R-mediated phagocytosis
bom04670  Leukocyte transendothelial migration
bom04713  Circadian entrainment
bom04720  Long-term potentiation
bom04723  Retrograde endocannabinoid signaling
bom04724  Glutamatergic synapse
bom04725  Cholinergic synapse
bom04726  Serotonergic synapse
bom04727  GABAergic synapse
bom04728  Dopaminergic synapse
bom04730  Long-term depression
bom04750  Inflammatory mediator regulation of TRP channels
bom04911  Insulin secretion
bom04912  GnRH signaling pathway
bom04916  Melanogenesis
bom04918  Thyroid hormone synthesis
bom04919  Thyroid hormone signaling pathway
bom04921  Oxytocin signaling pathway
bom04925  Aldosterone synthesis and secretion
bom04926  Relaxin signaling pathway
bom04928  Parathyroid hormone synthesis, secretion and action
bom04929  GnRH secretion
bom04933  AGE-RAGE signaling pathway in diabetic complications
bom04935  Growth hormone synthesis, secretion and action
bom04960  Aldosterone-regulated sodium reabsorption
bom04961  Endocrine and other factor-regulated calcium reabsorption
bom04970  Salivary secretion
bom04971  Gastric acid secretion
bom04972  Pancreatic secretion
bom05017  Spinocerebellar ataxia
bom05022  Pathways of neurodegeneration - multiple diseases
bom05031  Amphetamine addiction
bom05032  Morphine addiction
bom05143  African trypanosomiasis
bom05146  Amoebiasis
bom05161  Hepatitis B
bom05163  Human cytomegalovirus infection
bom05164  Influenza A
bom05170  Human immunodeficiency virus 1 infection
bom05171  Coronavirus disease - COVID-19
bom05200  Pathways in cancer
bom05205  Proteoglycans in cancer
bom05206  MicroRNAs in cancer
bom05207  Chemical carcinogenesis - receptor activation
bom05214  Glioma
bom05223  Non-small cell lung cancer
bom05225  Hepatocellular carcinoma
bom05231  Choline metabolism in cancer
bom05415  Diabetic cardiomyopathy
bom05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:bom00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102278724 (PRKCA)
   04012 ErbB signaling pathway
    102278724 (PRKCA)
   04014 Ras signaling pathway
    102278724 (PRKCA)
   04015 Rap1 signaling pathway
    102278724 (PRKCA)
   04310 Wnt signaling pathway
    102278724 (PRKCA)
   04370 VEGF signaling pathway
    102278724 (PRKCA)
   04066 HIF-1 signaling pathway
    102278724 (PRKCA)
   04020 Calcium signaling pathway
    102278724 (PRKCA)
   04070 Phosphatidylinositol signaling system
    102278724 (PRKCA)
   04072 Phospholipase D signaling pathway
    102278724 (PRKCA)
   04071 Sphingolipid signaling pathway
    102278724 (PRKCA)
   04151 PI3K-Akt signaling pathway
    102278724 (PRKCA)
   04150 mTOR signaling pathway
    102278724 (PRKCA)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    102278724 (PRKCA)
   04540 Gap junction
    102278724 (PRKCA)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    102278724 (PRKCA)
   04650 Natural killer cell mediated cytotoxicity
    102278724 (PRKCA)
   04664 Fc epsilon RI signaling pathway
    102278724 (PRKCA)
   04666 Fc gamma R-mediated phagocytosis
    102278724 (PRKCA)
   04670 Leukocyte transendothelial migration
    102278724 (PRKCA)
  09152 Endocrine system
   04911 Insulin secretion
    102278724 (PRKCA)
   04929 GnRH secretion
    102278724 (PRKCA)
   04912 GnRH signaling pathway
    102278724 (PRKCA)
   04921 Oxytocin signaling pathway
    102278724 (PRKCA)
   04926 Relaxin signaling pathway
    102278724 (PRKCA)
   04935 Growth hormone synthesis, secretion and action
    102278724 (PRKCA)
   04918 Thyroid hormone synthesis
    102278724 (PRKCA)
   04919 Thyroid hormone signaling pathway
    102278724 (PRKCA)
   04928 Parathyroid hormone synthesis, secretion and action
    102278724 (PRKCA)
   04916 Melanogenesis
    102278724 (PRKCA)
   04925 Aldosterone synthesis and secretion
    102278724 (PRKCA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102278724 (PRKCA)
   04270 Vascular smooth muscle contraction
    102278724 (PRKCA)
  09154 Digestive system
   04970 Salivary secretion
    102278724 (PRKCA)
   04971 Gastric acid secretion
    102278724 (PRKCA)
   04972 Pancreatic secretion
    102278724 (PRKCA)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    102278724 (PRKCA)
   04961 Endocrine and other factor-regulated calcium reabsorption
    102278724 (PRKCA)
  09156 Nervous system
   04724 Glutamatergic synapse
    102278724 (PRKCA)
   04727 GABAergic synapse
    102278724 (PRKCA)
   04725 Cholinergic synapse
    102278724 (PRKCA)
   04728 Dopaminergic synapse
    102278724 (PRKCA)
   04726 Serotonergic synapse
    102278724 (PRKCA)
   04720 Long-term potentiation
    102278724 (PRKCA)
   04730 Long-term depression
    102278724 (PRKCA)
   04723 Retrograde endocannabinoid signaling
    102278724 (PRKCA)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102278724 (PRKCA)
  09158 Development and regeneration
   04360 Axon guidance
    102278724 (PRKCA)
  09159 Environmental adaptation
   04713 Circadian entrainment
    102278724 (PRKCA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102278724 (PRKCA)
   05206 MicroRNAs in cancer
    102278724 (PRKCA)
   05205 Proteoglycans in cancer
    102278724 (PRKCA)
   05207 Chemical carcinogenesis - receptor activation
    102278724 (PRKCA)
   05231 Choline metabolism in cancer
    102278724 (PRKCA)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    102278724 (PRKCA)
   05214 Glioma
    102278724 (PRKCA)
   05223 Non-small cell lung cancer
    102278724 (PRKCA)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    102278724 (PRKCA)
   05161 Hepatitis B
    102278724 (PRKCA)
   05171 Coronavirus disease - COVID-19
    102278724 (PRKCA)
   05164 Influenza A
    102278724 (PRKCA)
   05163 Human cytomegalovirus infection
    102278724 (PRKCA)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    102278724 (PRKCA)
   05143 African trypanosomiasis
    102278724 (PRKCA)
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    102278724 (PRKCA)
   05022 Pathways of neurodegeneration - multiple diseases
    102278724 (PRKCA)
  09165 Substance dependence
   05031 Amphetamine addiction
    102278724 (PRKCA)
   05032 Morphine addiction
    102278724 (PRKCA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102278724 (PRKCA)
   05415 Diabetic cardiomyopathy
    102278724 (PRKCA)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    102278724 (PRKCA)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    102278724 (PRKCA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bom01001]
    102278724 (PRKCA)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:bom04131]
    102278724 (PRKCA)
Enzymes [BR:bom01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     102278724 (PRKCA)
Protein kinases [BR:bom01001]
 Serine/threonine kinases: AGC group
  PKC family [OT]
   102278724 (PRKCA)
Membrane trafficking [BR:bom04131]
 Endocytosis
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    102278724 (PRKCA)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr C2 C1_1 Pkinase_C ABC1
Other DBs
NCBI-GeneID: 102278724
NCBI-ProteinID: XP_014334784
Position
Un
AA seq 707 aa
MTQQFRSWAHPSTASTWSAEGVLAEWSPSPWLPWGPWSPSPCGSYRIRVSGRGAAWTSLG
LCAPSWGHVCVCTAIIVAARVLPARRTRVPGSSRHAGPCLHMTVCCFVVHKRCHEFVTFS
CPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCVI
NVPSLCGMDHTEKRGRIYLKAEVTDEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPK
NESKQKTKTIRSTLNPRWDESFTFKLKPSDKDRRLSVEIWDWDRTTRNDFMGSLSFGVSE
LMKMPASGWXGRLSXXXXXXXXXPIPEGDEEGNVELRQKFEKAKLGPAGNKVISPSEDRR
QPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTM
VEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAA
EISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYI
APEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEA
VSICKGLMTKHPGKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVCGKGAEN
FDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVNPQFVHPILQSAV
NT seq 2124 nt   +upstreamnt  +downstreamnt
atgacccagcagttccgctcctgggcacacccgagcacggcatccacctggagtgctgag
ggtgtgctggccgagtggtcaccatccccctggctcccctggggaccttggtcccctagt
ccctgtggctcctatcgcatccgcgtctcaggccgaggagcagcgtggacgtcgcttggg
ctctgcgccccatcctggggccacgtgtgcgtgtgcacagccatcatcgtggctgcccgt
gtgctgcccgcacgacgcactcgtgtcccgggctcgtcacgtcacgcgggcccgtgtctg
cacatgacagtttgctgttttgtggttcacaagaggtgccatgaatttgttactttttct
tgtccgggggcggataaaggacccgacacagatgacccgaggagcaagcacaagttcaag
atccacacgtatggcagccccaccttctgtgatcactgtggctccctgctctacggactc
atccaccaggggatgaaatgtgacacctgtgatatgaacgtgcacaagcagtgcgtgatc
aacgtgcccagcctctgcgggatggaccacacagagaagaggggccgcatctatctgaag
gccgaggtcacggatgaaaagctgcacgtcacagtacgagacgcgaaaaacctaatccct
atggatccaaatgggctttcagatccttacgtgaagctgaagcttattcctgaccccaag
aacgagagcaaacagaaaaccaagaccatccgctcgacgctgaacccccggtgggacgag
tccttcacgttcaaattaaaaccttctgataaagaccggcgactgtccgtggaaatctgg
gactgggatcgaaccacacggaacgacttcatggggtccctttcctttggggtttcggag
ctgatgaagatgccggcaagcggatggtgaggaaggctgagtnnnnnnnnnnnnnnnnnn
nnnnnnntgccgatccccgaaggcgacgaggaaggcaacgtggagctcaggcagaaattc
gagaaagccaagcttggtcctgccggcaacaaagtcatcagtccctccgaggacaggaga
cagccttccaacaacctggacagagtgaagctcacggacttcaacttcctcatggtgctg
ggcaaaggcagctttgggaaggtgatgctggccgaccggaaggggacagaggagctgtac
gccatcaagatcctgaagaaggacgtggtcatccaggacgacgacgtggagtgcaccatg
gtggagaagcgggtcctggcgctgctcgacaagccgccgttcctgacgcagctgcactcc
tgcttccagacggtggaccggctgtacttcgtcatggagtacgtcaacggcggggacctc
atgtaccacatccagcaggttgggaagttcaaggagccgcaagcagtgttctatgcggca
gagatttccatcgggctgttctttcttcataaaagaggaatcatttatcgggacctgaag
ttagacaacgtcatgctggactcggaaggacacattaagatcgcggacttcgggatgtgc
aaggagcacatgatggatggcgtcacgaccaggaccttctgcgggacccccgactacatc
gccccagagataatcgcctatcagccgtacgggaagtccgtggactggtgggcctacggc
gtcctgttgtacgagatgttggctgggcagcctccgttcgacggcgaggacgaggacgag
ctgttccagtccatcatggagcacaacgtctcgtaccccaagtccttgtccaaggaggcc
gtgtccatctgcaaagggctgatgaccaagcaccccgggaagcggctgggctgcgggccc
gagggcgagcgggacgtgcgggagcatgccttcttccggaggatcgactgggagaagctg
gagaaccgcgagatccagccacccttcaagcccaaagtgtgcggcaaaggagcagagaac
tttgacaagttcttcacgcgagggcagcctgtcttgacgccgcccgaccagctggtcatc
gctaacatcgaccagtctgattttgaaggcttctcatacgtcaacccccagttcgtgcac
cccatcctgcagagcgcggtatga

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (72)   
   KEGG PATHWAY (72)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (6)   
   Pfam (6)   
All databases (90)   

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