KEGG   Bos mutus (wild yak): 102285317Help
Entry
102285317         CDS       T02919                                 

Gene name
INSR
Definition
(RefSeq) insulin receptor
  KO
K04527  insulin receptor [EC:2.7.10.1]
Organism
bom  Bos mutus (wild yak)
Pathway
bom04010  MAPK signaling pathway
bom04014  Ras signaling pathway
bom04015  Rap1 signaling pathway
bom04022  cGMP-PKG signaling pathway
bom04066  HIF-1 signaling pathway
bom04068  FoxO signaling pathway
bom04072  Phospholipase D signaling pathway
bom04150  mTOR signaling pathway
bom04151  PI3K-Akt signaling pathway
bom04152  AMPK signaling pathway
bom04211  Longevity regulating pathway
bom04213  Longevity regulating pathway - multiple species
bom04520  Adherens junction
bom04910  Insulin signaling pathway
bom04913  Ovarian steroidogenesis
bom04923  Regulation of lipolysis in adipocytes
bom04930  Type II diabetes mellitus
bom04931  Insulin resistance
bom04932  Non-alcoholic fatty liver disease (NAFLD)
bom04960  Aldosterone-regulated sodium reabsorption
Module
bom_M00676  PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:bom00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    102285317 (INSR)
   04015 Rap1 signaling pathway
    102285317 (INSR)
   04010 MAPK signaling pathway
    102285317 (INSR)
   04066 HIF-1 signaling pathway
    102285317 (INSR)
   04068 FoxO signaling pathway
    102285317 (INSR)
   04072 Phospholipase D signaling pathway
    102285317 (INSR)
   04022 cGMP - PKG signaling pathway
    102285317 (INSR)
   04151 PI3K-Akt signaling pathway
    102285317 (INSR)
   04152 AMPK signaling pathway
    102285317 (INSR)
   04150 mTOR signaling pathway
    102285317 (INSR)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    102285317 (INSR)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    102285317 (INSR)
   04923 Regulation of lipolysis in adipocyte
    102285317 (INSR)
   04913 Ovarian Steroidogenesis
    102285317 (INSR)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    102285317 (INSR)
  09149 Aging
   04211 Longevity regulating pathway - mammal
    102285317 (INSR)
   04213 Longevity regulating pathway - multiple species
    102285317 (INSR)
 09160 Human Diseases
  09166 Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    102285317 (INSR)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    102285317 (INSR)
   04931 Insulin resistance
    102285317 (INSR)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bom01001]
    102285317 (INSR)
  09183 Protein families: signaling and cellular processes
   04090 CD Molecules [BR:bom04090]
    102285317 (INSR)
Enzymes [BR:bom01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     102285317 (INSR)
Protein kinases [BR:bom01001]
 Receptor tyrosine kinases (RTK)
  INSR family [OT]
   102285317 (INSR)
CD molecules [BR:bom04090]
 Proteins
  102285317 (INSR)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Pkinase_Tyr Recep_L_domain Pkinase Furin-like fn3 Kinase-like B2 DUF4476
Motif
Other DBs
NCBI-GeneID: 102285317
NCBI-ProteinID: XP_005890820
Position
Un
AA seq 1382 aa AA seqDB search
MGAGGGRGAAAVLLMVVVAALLVGAAGHLYPGEVCPGMDIRNNLTRLHELANCSVIEGHL
QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL
VIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE
ECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTSEGLCCHSECL
GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHNKCKNSRRQG
CHQYVIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGC
TIINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL
EIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE
RNDIALKTNGDQASCENELLKFSYIRTSYDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQ
NVTEFDGQDACGSNSWTVVDIDPPTRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFS
DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWE
RQAEDSELYELDYCLKGLKLPSRTWSPPFESEGSQKHNQSEYEESAGECCSCPKTDSQIL
KELEESSFRKTFEDYLHNVVFIPRKSSSGPVAEDARPSRKRRALGDVGNVTAAVPTALGL
PNTSSTSTPMSSEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDSPEERCSVAAYV
SARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGEEELHLCV
SRRHYALERGCRLRGLLPGNYSVRVRATSLAGNGSWTEATYFYVTDYLDVPSNIAKIIIG
PLIFVFLFSVVIGSICLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPR
EKITLLRELGQGSFGMVYEGNARDIVKGEAETRVAVKTVNESASLRERIEFLNEASVMKG
FTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMA
AEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPV
RWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDN
CPERVTDLMRMCWQFNPKMRPTFLEIVDLLKDDLHPSFPEVSFFHSEENKAPESEELEME
FEDMESVPLDRASHAQREEAGGRDGGSALGLKRNYDEHIPYTHMNGGKKNGRILTLPRSN
PS
NT seq 4149 nt NT seq  +upstreamnt  +downstreamnt
atgggcgccgggggcgggaggggggcggcagccgtgctgctgatggtggtcgtcgccgcg
ctgctggtgggcgccgcgggccacctgtaccctggagaagtgtgccccggtatggatatc
cggaataatctcacccggctgcatgagctggccaactgctcagtcatcgaaggacatttg
cagattctgttgatgttcaaaacgagacctgaggacttccgagacctcagtttccccaaa
ctcatcatgatcactgattacttgctgctcttccgggtctatgggctggagagcctgaag
gacttgttccccaacctcacggttatccgaggctcacgcctcttctttaattatgcgctg
gtcatctttgagatggttcacctgaaggagcttggcctctacaacctgatgaacatcacc
cgggggtctgtccgcattgagaagaacaatgaactctgctacctggccaccatcgactgg
tctcgcatcctggattccgtggaggataattatatcgtgctgaacaaagacgacaatgag
gagtgtggggacatttgtccaggcaccgccaagggcaagaccaactgccctgccactgtc
atcaacgggcaatttgtggagcggtgctggacacacagccactgccagaaagtgtgtccg
accatctgcaagtcacatggctgcacctctgagggtctctgctgccacagcgagtgcttg
ggcaactgctcagagcccgacgaccccaccaagtgtgtggcctgtcgcaacttctacctg
gacggcaggtgtgtggagacctgcccgcccccttactaccacttccaagactggcgctgc
gtgaacttcagcttctgccaggacctgcacaacaaatgcaagaactctcggaggcaaggc
tgccaccagtatgtcattcacaataacaagtgcatccccgagtgcccctctggctacacg
atgaattccagcaacttgatgtgtaccccttgcctgggcccctgtcccaaggtatgccac
ctcctggaaggcgagaagaccatcgattcggtgacatctgcccaggagctccgaggctgc
accatcatcaacggaagcttaatcatcaacattcgagggggcaacaacctggcagctgag
ctagaggccaaccttggactcattgaagaaatttcaggatatctgaaaatccgccggtcc
tatgccctggtgtcactttccttcttccggaagttacgtctgattcgaggggagaccttg
gaaattgggaactactctttctacgccttggacaaccagaacctaaggcagctgtgggac
tggagcaaacacaacctcaccatcactcaggggaaactcttcttccactataaccccaaa
ctctgcctgtcggaaattcacaagatggaggaagtttcaggaaccaaggggcgccaggag
agaaatgacattgctctaaagaccaatggggaccaggcatcctgtgaaaatgaattactt
aaattttcttacattcggacatcttacgacaagatcttgctgaaatgggagccgtattgg
cctcctgacttccgagacctcctggggttcatgttgttctacaaagaggccccttaccag
aacgtgacagaattcgatgggcaggatgcgtgcggctccaacagctggacagtggtggat
attgacccgcctacgaggtccaacgaccccaagtcacagaaccaccctgggtggctgatg
cgtggtctcaagccctggacccagtatgccatctttgtcaagaccctggtcaccttttct
gatgaacgccgtacatacggggccaagagtgacatcatctatgtccagacagacgccact
aatccttccgtgcccctggatcccatctcagtttctaattcctcgtcccagattattctg
aaatggaagcctccctccgaccccaatggcaatatcacacactacttggtgttctgggag
agacaggcggaagacagtgagctgtatgaactggattattgcctcaaagggttgaagctg
ccctcccggacctggtctccaccattcgagtcggagggctcccagaagcacaatcagagt
gagtatgaggagtctgctggtgaatgctgctcctgcccaaagaccgactcgcagatcctc
aaggagctggaggagtcctcgttcaggaaaacgtttgaagattacctgcacaacgtggtt
tttatccccagaaaatcatcttcaggccctgttgccgaggacgctaggccttcgaggaaa
cgcagagcccttggtgacgtggggaatgtgacagcagccgtgcccaccgctctggggctc
cccaatacctcctccaccagcacgcccatgagctcggaggagcacagacccttcgagaaa
gtggtgaacaaggagtcgctggtcatctccggcctgcgtcactttactggctatcgaatc
gagcttcaggcttgcaaccaagattcccccgaggagaggtgtagcgtggctgcctatgtc
agcgccaggaccatgcctgaagccaaggcagatgatattgttggccccgtgacccatgaa
atcttcgagaacaacgttgttcacttgatgtggcaggagcccaaggaacccaacggtctg
attgtgctgtatgaagtgagttaccgacgatacggcgaggaggagctgcacctctgcgtc
tcccgccgacattatgctctggagcgtggctgccggctgcgtgggctgctgcctgggaat
tacagtgtgcgagttcgggccacctccctggcaggcaatgggtcttggacggaagccacc
tatttctacgtgacagactatttagacgtgccatcaaatattgcaaaaatcatcatcggt
cccctcatctttgtctttctcttcagtgttgtgattggaagtatttgtctattcctgaga
aagaggcagccagatgggccattgggaccactgtatgcttcttcaaacccagagtacctc
agtgccagcgatgtgtttccatgctctgtgtatgtgccggacgagtgggaggtgcctcga
gagaagatcacactcctgcgagaattggggcaaggctcctttggcatggtgtacgagggc
aacgccagggacattgtcaagggtgaggcggagacgcgcgtggcagtgaagacggtcaac
gagtcagccagcctgcgagagcggatcgagtttctcaacgaggcttcggtcatgaagggc
ttcacctgccaccatgtggtccgcctcctgggggtggtgtccaaaggccagccaacgctg
gtggtgatggagttgatggctcacggagacctgaagagttacctccgttccctgcggcct
gaggctgagaataaccccggccgccctccgcctaccctgcaagaaatgattcagatggcg
gcagagatcgccgatgggatggcatacctgaacgctaagaagttcgtgcaccgggatctt
gcagcccggaactgcatggttgcccacgactttacagtcaaaattggagactttggaatg
acaagagacatctatgaaacggattactaccggaaagggggcaaaggtctgctccccgtg
cggtggatggcacctgaatccctgaaggacggagtcttcaccacctcttcagacatgtgg
tcttttggtgtggtcctttgggaaattaccagcttggcagaacagccttaccaaggtcta
tcaaatgagcaggtgctgaaatttgtcatggatggagggtacctggatcaacctgacaat
tgtccagagagagtcaccgacctgatgcggatgtgctggcagttcaaccccaagatgcgt
ccaaccttcctggagatcgtggacctgctcaaggacgacctgcaccccagctttcccgaa
gtgtccttcttccacagcgaggagaacaaggcgcccgagagcgaggagctggagatggag
tttgaggacatggagagcgtgcccctggaccgggcctcgcacgcgcagagagaggaggcc
gggggccgggatggagggtcggcgctggggctaaagcgaaactatgacgagcacatcccc
tacacccacatgaacgggggcaagaaaaacggacggattctgactttgccccggtcaaat
ccttcctaa

DBGET integrated database retrieval system