KEGG   Bos mutus (wild yak): 102285710
Entry
102285710         CDS       T02919                                 
Symbol
RPS6KB1
Name
(RefSeq) ribosomal protein S6 kinase B1
  KO
K04688  ribosomal protein S6 kinase beta [EC:2.7.11.1]
Organism
bom  Bos mutus (wild yak)
Pathway
bom01521  EGFR tyrosine kinase inhibitor resistance
bom01522  Endocrine resistance
bom04012  ErbB signaling pathway
bom04066  HIF-1 signaling pathway
bom04140  Autophagy - animal
bom04150  mTOR signaling pathway
bom04151  PI3K-Akt signaling pathway
bom04152  AMPK signaling pathway
bom04211  Longevity regulating pathway
bom04213  Longevity regulating pathway - multiple species
bom04350  TGF-beta signaling pathway
bom04371  Apelin signaling pathway
bom04666  Fc gamma R-mediated phagocytosis
bom04714  Thermogenesis
bom04910  Insulin signaling pathway
bom04931  Insulin resistance
bom05163  Human cytomegalovirus infection
bom05165  Human papillomavirus infection
bom05170  Human immunodeficiency virus 1 infection
bom05200  Pathways in cancer
bom05205  Proteoglycans in cancer
bom05207  Chemical carcinogenesis - receptor activation
bom05210  Colorectal cancer
bom05212  Pancreatic cancer
bom05221  Acute myeloid leukemia
bom05224  Breast cancer
bom05225  Hepatocellular carcinoma
bom05226  Gastric cancer
bom05231  Choline metabolism in cancer
bom05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:bom00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    102285710 (RPS6KB1)
   04350 TGF-beta signaling pathway
    102285710 (RPS6KB1)
   04371 Apelin signaling pathway
    102285710 (RPS6KB1)
   04066 HIF-1 signaling pathway
    102285710 (RPS6KB1)
   04151 PI3K-Akt signaling pathway
    102285710 (RPS6KB1)
   04152 AMPK signaling pathway
    102285710 (RPS6KB1)
   04150 mTOR signaling pathway
    102285710 (RPS6KB1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    102285710 (RPS6KB1)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    102285710 (RPS6KB1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    102285710 (RPS6KB1)
  09149 Aging
   04211 Longevity regulating pathway
    102285710 (RPS6KB1)
   04213 Longevity regulating pathway - multiple species
    102285710 (RPS6KB1)
  09159 Environmental adaptation
   04714 Thermogenesis
    102285710 (RPS6KB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102285710 (RPS6KB1)
   05205 Proteoglycans in cancer
    102285710 (RPS6KB1)
   05207 Chemical carcinogenesis - receptor activation
    102285710 (RPS6KB1)
   05231 Choline metabolism in cancer
    102285710 (RPS6KB1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    102285710 (RPS6KB1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    102285710 (RPS6KB1)
   05212 Pancreatic cancer
    102285710 (RPS6KB1)
   05225 Hepatocellular carcinoma
    102285710 (RPS6KB1)
   05226 Gastric cancer
    102285710 (RPS6KB1)
   05221 Acute myeloid leukemia
    102285710 (RPS6KB1)
   05224 Breast cancer
    102285710 (RPS6KB1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    102285710 (RPS6KB1)
   05163 Human cytomegalovirus infection
    102285710 (RPS6KB1)
   05165 Human papillomavirus infection
    102285710 (RPS6KB1)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    102285710 (RPS6KB1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    102285710 (RPS6KB1)
   01522 Endocrine resistance
    102285710 (RPS6KB1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bom01001]
    102285710 (RPS6KB1)
Enzymes [BR:bom01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     102285710 (RPS6KB1)
Protein kinases [BR:bom01001]
 Serine/threonine kinases: AGC group
  RSK family [OT]
   102285710 (RPS6KB1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Pkinase_C Kinase-like Pkinase_fungal ABC1 DUF1015
Other DBs
NCBI-GeneID: 102285710
NCBI-ProteinID: XP_005892359
Position
Un
AA seq 472 aa
MDHGGVGPYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTG
ANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILE
YLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVK
LTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPF
TGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFR
HINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSALSESANQVFLGFTY
VAPSVLESVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVE
YPMETSGIEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL
NT seq 1419 nt   +upstreamnt  +downstreamnt
atggaccatgggggagttggaccatatgaacttggcatggaacattgtgagaaatttgaa
atctcagaaactagtgtgaacagagggccagaaaaaatcagaccagaatgttttgagctc
cttcgagtacttggtaaagggggctatggaaaggtttttcaagtacgaaaagtaacagga
gcaaataccgggaaaatatttgccatgaaggtgcttaaaaaggcaatgatagtaagaaat
gctaaagatacagctcatacaaaagcagaacggaatattctggaggaagtaaagcatcct
ttcattgtggatttaatttatgcctttcagaccggtggaaaactctacctcatccttgag
tatctcagcggaggagaattatttatgcagttagaaagagaaggaatatttatggaagac
acagcctgcttttacttggcagaaatctccatggctttggggcatttacatcaaaagggg
atcatctacagagacctgaagccggagaatatcatgcttaatcaccaaggtcacgtcaaa
ctaacagattttggactatgcaaagaatctattcatgacggaacagtcacacacaccttt
tgtggaacaatagaatacatggcccctgagatcttgatgagaagtggccacaatcgtgct
gtggattggtggagtttgggagcattaatgtatgacatgctgactggagcacccccgttc
actggggagaatagaaagaaaacaattgacaaaatcctcaaatgtaaactcaatttgcct
ccctacctcacgcaagaagccagagatctgcttaaaaagctgctgaaaagaaatgctgct
tctcgtcttggagctggtcctggggatgctggagaagttcaagctcatccattcttcaga
catattaactgggaagaactgctggctcggaaggtggagccccccttcaaacctcttttg
caatcagaagaggatgtgagtcagtttgattccaagtttacacgtcagacacctgttgac
agcccagatgactcagctctcagtgaaagtgccaaccaggtctttctgggttttacatat
gtggctccatctgtacttgaaagcgtgaaagaaaagttttcctttgaaccaaaaatccga
tcccctcgaagatttattggcagcccacgaacacctgtcagcccagtcaaattttctcct
ggggatttctggggaagaggtgcttcagccagcacggcaaatccgcagacgcctgtggaa
taccccatggaaacaagtgggatagagcagatggacgtgacgatgagcggggaggcttca
gcaccgcttccaatacgacagccaaactccggaccgtacaaaaagcaagcttttcccatg
atctccaaacgaccagagcacctgcgtatgaatctatga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (30)   
   KEGG PATHWAY (30)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (7)   
   Pfam (7)   
All databases (52)   

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