KEGG   Boleophthalmus pectinirostris (great blue-spotted mudskipper): 110159759
Entry
110159759         CDS       T05002                                 
Symbol
top2a
Name
(RefSeq) DNA topoisomerase 2-alpha
  KO
K03164  DNA topoisomerase II [EC:5.6.2.2]
Organism
bpec  Boleophthalmus pectinirostris (great blue-spotted mudskipper)
Brite
KEGG Orthology (KO) [BR:bpec00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:bpec03032]
    110159759 (top2a)
   03036 Chromosome and associated proteins [BR:bpec03036]
    110159759 (top2a)
Enzymes [BR:bpec01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.2  DNA topoisomerase (ATP-hydrolysing)
     110159759 (top2a)
DNA replication proteins [BR:bpec03032]
 Eukaryotic type
  DNA Topoisomerases
   110159759 (top2a)
Chromosome and associated proteins [BR:bpec03036]
 Eukaryotic type
  Chromosome condensation proteins
   Other regulators of chromosome condensation
    110159759 (top2a)
  Centrosome formation proteins
   Centriole proteins
    110159759 (top2a)
SSDB
Motif
Pfam: DNA_topoisoIV TOPRIM_C DNA_gyraseB HATPase_c Toprim DTHCT
Other DBs
NCBI-GeneID: 110159759
NCBI-ProteinID: XP_020780028
Position
Unknown
AA seq 1572 aa
MAEPLKSLFENKPVEKTKKDPKRLSVERIYQKKTQLEHILLRPDSYIGSVEPVTQQMWVY
DEDVGLNCRDITFVPGLYKIFDEILVNAADNKQRDSSMSCIKVNIDVENNTISVWNNGKG
IPVVEHKVEKVYVPALIFGQLLTSSNYNDDQKKVTGGRNGYGAKLCNIFSTKFTVQTACK
ESGKAFKQTWYDNMGRAGDVSIKPFSGEDHTCITFKPDLPKFKMTILDKDTVALMTRRAY
DIAGSTKGVRVFLNGNRLPIVDFRSYVDLYLKDKVNEVGEPLKVIHEAVNGRWEVCLTMS
EKGFQQVSFVNSIATTKGGRHVDYVADQVISKLIDVVKKKNKAGVIVKPFQVKNHMWLFV
NCLIENPTFDSQTKENMTLQQKSFGSTCPLTEKFIKQAITCGIVESVMNWVRFKAQTQLN
KKCSAVKHTKIKGVPKLDDANDAGGKNSIGCTLILTEGDSAKTLAVSGLGVIGRDRYGVF
PLRGKMLNVREASHKQIMENAEINNIIKILGLQYKKNYTDPESLKTLRYGKLMIMTDQDQ
DGSHIKGLLINFIHHNWPSLLRHNFLEEFITPIIKASHKKTQLSFYSIPEFNEWKESQAN
IKSWKIKYYKGLGTSTSQEAKEYFSDMHRHRIPFKYSGPEDDEAITLAFSKKKCDERKEW
LTKFMTDRRQRREHNLPEDYLYGQATKSLSYNDFVNKELVLFSNSDNERSIPCLVDGLKP
GQRKVMFCCFKRNDKREVKVAQLAGSVAEMSAYHHGEGSLMMTIVGLAQNFVGSNNLNLL
QPLGQFGTRLHGGKDSASPRYIFTMLSPLARLVFPQMDDNLLKYNYDDNQRVEPEWYIPI
IPTVLVNGSDGIGTGWASKIPNYDIREIITNIYRMLNGEEPQPMVFPCDYSLPSYKGFRG
TIDQVMDNSYLNSGEVSIIDSETIEISELPIKIWTQTYKENVLEPMLNGTEKVPALITDY
KDYHTDTTVRFVVKMTPEKLREAEAAGLHKVFKLQNSLTCNSMVLFDHVGSLKKYETVQE
IMKDFFELRMKYYVLRKDWMTGMLKAENSKLSNQARFILEKIQGTLVIENKPKKELIRML
QEMGYDSDPVKAWKQAQEKNEEEMEEDGDEEKEKEDTTGPDYNYLLSMPMWYLTKEKKDE
LCKQRDAKCAELNTLKNKSPSDLWREDLAAFSEELERIEAKEKEEAAAPAKGAKGKLMKV
KKETLPTPQGRRVIPRVTSTMKAEAHKKKGVGKRVKGEDIVMKMEFGDDGEPIEVPTESG
LVVPPTKKARAPKKPKVADGDPVEVSEEMGLAAQLTKKTKTTTKEKAQKLKKNKWSDDEG
ESEDSMETKEPAASRERVVRKAKAAVKYSMSSDEDSEDDFDDWGKTNKTSKKMGMSDDDS
FAPDFSLNKSDMDSPVRKPAAKKPAKSKMAKTTEVKVNSSDGQEAPSKPVAQPKAKTVAA
KKPAGAKKAPAPKKKTLGDAKQPSILDALSKPKATSKMTDKKVPSFNSSDSEAEVKAPAP
KDKVLKRKQAMSDDSDSESDNLMVRLKAKNTAGNKKTKKWEDDESFEAEPPVQVKSSRTK
KTNYVLDSDSDE
NT seq 4719 nt   +upstreamnt  +downstreamnt
atggcagagccactaaagtccctgtttgaaaacaagccagtggaaaagacaaagaaggac
ccaaaacggttgtctgtggagaggatctatcagaagaaaactcagctggagcacattttg
cttagaccagactcctacattggctctgttgagcctgttacacagcaaatgtgggtctat
gatgaggatgtgggattgaactgtcgtgatataacatttgtccctggtctttacaaaatc
tttgatgaaattcttgtaaatgctgctgacaataagcagagggattcgagcatgtcatgt
atcaaagtcaacattgatgttgaaaacaacaccatcagtgtttggaataatggaaagggt
atacctgtcgtggagcataaagttgaaaaagtgtatgtgcctgctctcatttttgggcag
ctcctcacctccagcaactacaatgacgaccagaagaaagtcacaggtggacgtaacggt
tatggagccaagctttgcaacatctttagtaccaagttcactgtgcagactgcatgtaaa
gaatcgggcaaggcttttaagcagacctggtatgacaacatgggcagggctggggatgtc
agcatcaaaccctttagtggagaagatcacacttgcatcaccttcaaaccagatctgccc
aagttcaagatgaccattttggacaaggacactgttgctctgatgactcgcagggcttat
gatattgctggctccactaaaggggtccgtgtgttccttaatgggaatcggctgccaatt
gtggatttccgcagttatgtggacttgtatttgaaggacaaagtgaatgaggtgggagag
ccccttaaagtaatccatgaagctgtcaatgggcgttgggaggtctgccttaccatgagt
gaaaagggtttccaacaagtcagctttgtcaacagcattgctacaacaaagggtggaaga
catgttgactatgtcgctgaccaggtcatttcaaagctcatagatgtggtcaagaagaaa
aacaaagctggagttattgtcaagccatttcaggtgaagaaccacatgtggctctttgtg
aactgtctgattgagaatccaacctttgactctcagaccaaagaaaacatgactctgcag
cagaaaagctttggctctacctgccccctcactgaaaaatttatcaaacaggctatcacc
tgtggcattgtggaaagtgttatgaactgggtcagatttaaggctcagacacagctcaac
aagaaatgctctgctgtcaaacacacaaaaatcaaaggggtaccgaaactggatgatgcc
aatgatgcgggaggaaagaattccattggctgtactcttatcctcactgagggagactcg
gccaaaacactggctgtgtctggtcttggtgtaattggtagggaccgctatggtgtcttc
cctctcagaggaaaaatgctcaatgttcgagaagcctctcataaacagataatggagaat
gctgagatcaacaatatcataaaaattcttggactgcagtacaagaaaaactacactgac
cctgaatctctgaagaccttgcggtatggcaagctcatgattatgacagatcaggatcaa
gatggctcccacattaaaggcctactcatcaacttcattcaccacaactggccttcactg
ctgcgtcacaactttctggaagagttcataactcccattatcaaggcatcccacaagaaa
acacagctgtccttttacagtattccagagttcaatgaatggaaagaaagccaggcaaac
atcaaatcttggaaaatcaaatactacaaaggtttgggtactagcacatcacaggaggcc
aaggaatacttctccgatatgcatagacatcgcattccatttaaatactctgggcctgag
gatgatgaagctattacacttgcctttagcaagaaaaaatgtgatgagcgtaaagaatgg
cttacaaagttcatgactgacaggcgacagcgccgagagcacaacttgccagaggactac
ctgtatggtcaggccaccaaatctctttcctacaacgactttgtcaacaaagaacttgtc
cttttctccaactctgacaatgaaaggtctattccttgccttgtggatggcctcaaacct
ggccagaggaaggtgatgttctgttgcttcaagaggaatgacaaacgtgaggtcaaggtg
gcacagttggctggttctgtggcagagatgtctgcataccatcatggagagggctccctg
atgatgaccattgttggtttggctcagaattttgttggcagcaacaacttgaatcttttg
cagcctcttggtcagtttggtactcggctgcatggtggcaaggactctgccagccctcga
tatattttcactatgctcagtcctctggctcgccttgttttccctcaaatggatgacaac
ttgttgaagtacaactatgatgataaccagcgtgttgagcccgagtggtacattcccatc
atccccacagtgctggtgaatggatcagacggcattggcacagggtgggccagcaagatc
cccaactatgacatccgagagatcatcaccaacatctaccgcatgctgaatggagaggag
ccccagcccatggtgttcccctgtgactattcgctcccaagctacaaaggcttcaggggc
acaatagatcaggtcatggataacagttacttgaacagtggagaagtctctatcattgac
tcagagaccattgagatctctgaattacccatcaaaatatggacacagacctacaaggag
aatgtactggagccaatgttaaatggcacagaaaaggtccctgctctgatcacagactac
aaggactaccacacagacaccacagtgcgttttgtggtgaagatgaccccagagaaactg
agggaggctgaagctgcaggacttcataaagtctttaagctacaaaacagcctcacctgt
aactccatggtcctgtttgaccatgtgggcagtctgaagaaatacgagacagtacaagaa
ataatgaaggatttctttgagttgagaatgaagtactatgtgctcaggaaagactggatg
acaggcatgctgaaagcagagaactcaaagctcagcaaccaggcccgcttcatcctagag
aagatccaagggaccttggttatcgaaaacaagccaaagaaggagttgatccgaatgcta
caggagatgggctacgattctgacccagttaaagcctggaaacaagcacaagagaagaat
gaagaggagatggaagaagatggagatgaggagaaggagaaagaagacacaactgggcca
gattacaactaccttctgtctatgcctatgtggtacttgaccaaagaaaagaaggatgag
ctctgcaaacaaagggatgccaagtgcgcagagctgaacacgctaaagaacaagtctcca
tctgatctatggagagaagatcttgctgctttctctgaagaattagagcgcattgaagcc
aaagagaaggaagaagctgctgcacctgcaaagggagcaaaaggcaaattgatgaaagtc
aaaaaggagactcttcctaccccccaaggccgacgtgtgattccccgggtcaccagcaca
atgaaggctgaggcccacaaaaagaaaggagtgggcaagagagtcaagggtgaagatata
gtgatgaaaatggaatttggggatgatggagagccaatagaagtacccacagagagtggc
cttgtagtaccccccactaagaaagcaagggcccccaaaaagcccaaagtggcggatgga
gatcctgtagaggtgtctgaggagatgggacttgcagcacaactaacgaagaaaaccaaa
actacaactaaggagaaggcccaaaaactgaagaaaaataagtggtcagatgatgaggga
gaatctgaggactccatggaaaccaaagaaccagcagcctcaagagaaagagttgtacgc
aaagctaaagctgcggtcaagtacagcatgtccagcgatgaggatagtgaggatgatttt
gatgactggggaaagacaaacaaaacaagcaaaaaaatgggaatgagtgatgatgacagc
tttgcaccggattttagccttaacaaaagcgatatggactctcctgtacgcaaaccagct
gctaagaaacctgcaaagagcaagatggctaaaacaacagaggtcaaagtcaattcttct
gacggtcaagaggctccatccaaaccagtggctcaacctaaagcaaagacggttgcagca
aagaaacctgctggggccaagaaagctcctgcacccaagaagaagacactaggagacgca
aagcagccctccatcttggatgccctctcaaaacccaaagctacgtccaagatgacagac
aagaaagtgccttcattcaattccagtgactctgaggctgaagtgaaagcacctgctccg
aaggacaaggtactcaaacgcaagcaggcaatgagcgatgactcagacagtgaatcggac
aacctcatggtgcgactcaaagctaaaaacacagctggaaacaagaaaacaaaaaagtgg
gaggatgatgagagttttgaggcagaaccaccagtacaagtgaaatcctctcgaactaag
aaaacaaattacgtcctggattcagactctgatgaataa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (37)   
   KEGG ORTHOLOGY (1)   
   RefGene (33)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (6)   
   Pfam (6)   
All databases (51)   

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