KEGG   Burkholderia pseudomallei HBPUB10134a: DR55_5457
Entry
DR55_5457         CDS       T03422                                 
Symbol
bkdA1
Name
(GenBank) 2-oxoisovalerate dehydrogenase subunit alpha
  KO
K00166  2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
Organism
bpsh  Burkholderia pseudomallei HBPUB10134a
Pathway
bpsh00280  Valine, leucine and isoleucine degradation
bpsh00640  Propanoate metabolism
bpsh00785  Lipoic acid metabolism
bpsh01100  Metabolic pathways
bpsh01110  Biosynthesis of secondary metabolites
bpsh01210  2-Oxocarboxylic acid metabolism
Module
bpsh_M00036  Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:bpsh00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00640 Propanoate metabolism
    DR55_5457 (bkdA1)
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    DR55_5457 (bkdA1)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    DR55_5457 (bkdA1)
Enzymes [BR:bpsh01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.4  3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
     DR55_5457 (bkdA1)
SSDB
Motif
Pfam: E1_dh OxoDH_E1alpha_N TPP_enzyme_C LutB_C DXP_synthase_N
Other DBs
NCBI-ProteinID: AIP55354
Position
2:2632998..2634230
AA seq 410 aa
MSQYGPLRLHVPEPTGRPGCKTDFSYLRLSPAGKVRKPPIDVAPADTSDLAYGLVRVLDE
HGRAVGPWAPDLDPDILRKGIRAMLKTRIFDARMQIAQRQKKISFYMQCLGEEAIAVAHT
LALERGDMCFPTYRQQGILMVREYPLVDMMCQLMSNERDPLKGRQLPVMYSTRDAGFFSI
SGNLATQFIQAVGWAMASAIKGDTRIASAWIGDGATAEADFHTALTFAHVYRAPVILNVV
NNQWAISTFQAIAGGEGATFAGRGVGCGIASLRVDGNDFLAVYAASRWAAERARRNLGPT
LIEWVTYRAGPHSTSDDPTKYRPGDDWTNFPLGDPLERLKRHMIGIGVWSEQDHEDTKAA
LEAEVLAAQKEAERYGTLADEHVPNVASIFEDVYKEMPAHLRRQRQQLGV
NT seq 1233 nt   +upstreamnt  +downstreamnt
atgagccagtacgggccattgcgattgcatgtgccggagcctaccgggcgtccgggatgc
aagaccgatttttcttacctgcgcctgtcgccagccggcaaggtgcgcaaaccccccatc
gacgtcgcccccgccgacacgagcgacttggcctatggcctcgtgcgcgtgctcgacgag
cacggacgagcggtcgggccatgggcgcccgacctcgatcccgacatcttgcgcaaaggc
atccgcgcgatgctgaagacgcgcatcttcgacgcgcgcatgcagatcgcgcagcgccag
aagaagatctcgttctacatgcagtgcctcggcgaggaagcgatcgcggtcgcgcacacg
ctcgcgctcgagcgcggcgacatgtgctttccgacgtatcggcagcaagggatcctgatg
gtgcgcgagtatccgctcgtcgacatgatgtgccagctgatgtcgaacgagcgcgatccg
ctgaagggccgccagttgccggtgatgtactcgacgcgcgacgcgggcttcttctcgatc
tcgggcaatctcgcgacgcagttcatccaggcggtcggctgggcgatggcctcggcgatc
aagggcgacacgcgcatcgcttccgcgtggatcggcgacggcgcgacggccgaagccgat
ttccataccgcgctcacgttcgcacacgtgtaccgcgcgcccgtgatcctgaacgtggtc
aacaaccagtgggcgatctcgacgttccaggcgatcgcgggcggcgagggcgcgaccttc
gccgggcgcggcgtcggctgcggcatcgcttcgctgcgcgtggacggcaacgatttcctc
gcggtctacgccgcgtcccgctgggcggccgaacgcgcgcgccgcaacctcgggccgacg
ctgatcgagtgggtcacgtaccgcgcgggcccgcactcgacgtccgacgatccgaccaag
taccgccccggcgacgactggacgaacttcccgctcggcgatccgctcgagcgcctgaag
cgccacatgatcggcatcggcgtgtggtccgagcaggaccacgaggacacgaaggccgcg
ctcgaggccgaggtgctcgccgcgcagaaggaagcggagcgctacggcacgctggccgac
gagcacgtgccgaacgtcgcgagcattttcgaggacgtctacaaggagatgcccgcgcac
ctgcgccggcagcgccaacagctcggggtttga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (22)   
   KEGG COMPOUND (22)   
Chemical reaction (15)   
   KEGG ENZYME (1)   
   KEGG REACTION (14)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (5)   
   Pfam (5)   
All databases (55)   

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