KEGG   Burkholderia pseudomallei 1026b: BP1026B_I0278
Entry
BP1026B_I0278     CDS       T02049                                 
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamino pimelate--D-alanyl-D-alanyl ligase
  KO
K01929  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
Organism
bpz  Burkholderia pseudomallei 1026b
Pathway
bpz00300  Lysine biosynthesis
bpz00550  Peptidoglycan biosynthesis
bpz01100  Metabolic pathways
bpz01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:bpz00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    BP1026B_I0278 (murF)
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    BP1026B_I0278 (murF)
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    BP1026B_I0278 (murF)
Enzymes [BR:bpz01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.10  UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
     BP1026B_I0278 (murF)
SSDB
Motif
Pfam: Mur_ligase_M Mur_ligase_C Mur_ligase
Other DBs
NCBI-ProteinID: AFI64944
UniProt: A0A0H3HLK0
Position
1:279790..281163
AA seq 457 aa
MIPGATVLGDERASFERVSTDSRSAGPGDLFVALKGERFDAHDFVGDVAARGASAAIVSR
SPAEWNLPALKVADTRAALGALAHGWRMRFSMPLVAVTGSNGKTTVKEMIASIFAAAVGE
HARLATAGNFNNDVGLPLTLLRLNAAHRLAVVELGMNHPGETEMLAKIAAPTVALVNNAQ
REHQEFMATVEAVALEHAAVIHALGPDGVAVFPADDAYAGIWRVAATGNRIVDFALHGAA
GGAPAAVTGALDGSLLVIDTPGARIDVRLNALGEHNARNALAATAAALAAGVPLAAIKAG
LEAFAPVKGRLQVARAAAGSLAGATVIDDTYNANPDSMRAAIDVLAAQSAPRVLVIGEMG
EVGDEGPAFHREIGAYARERGIDALFALGAATRPACDAYGAGARHFDDAAALVAALLAAN
FGAHATLLVKGSRFMKMERVVDALANETASGAAPDAH
NT seq 1374 nt   +upstreamnt  +downstreamnt
atgattcccggcgcgaccgtgctcggcgacgagcgcgcgtcgttcgagcgggtgtcgacg
gacagccgctcggcgggcccgggcgatctgttcgtcgcgctgaagggcgagcgtttcgat
gcgcacgatttcgtcggcgacgtcgccgcgcgcggcgcgagcgccgcgatcgtgtcgcgc
agcccggccgaatggaatctgcccgcgctgaaggtcgcggatacgcgcgccgcgctcggc
gcgctcgcgcacggctggcggatgcgcttctcgatgccgctcgtcgcggtgacgggcagc
aacggcaagacgaccgtgaaggaaatgatcgcgtcgatcttcgcggcggccgtcggtgag
cacgcgcgcctcgcgacggcgggcaacttcaacaacgacgtcggtctgccgctcacgctg
ctgcgccttaacgccgcgcatcggctcgcggtcgtcgagctcgggatgaatcatccgggc
gagaccgaaatgctcgcgaaaatcgccgcgccgacggtcgcgctcgtcaacaacgcgcag
cgcgagcatcaggaattcatggcgacggtcgaggcggtcgcgctcgagcatgcggccgtc
atccatgcgctcgggccggacggcgtcgcggtgtttccggccgacgacgcgtacgcgggc
atctggcgcgtcgcggcgaccggcaaccggatcgtcgatttcgcgctgcacggcgccgcc
ggcggcgcgcctgccgcggtgacgggcgcgctcgacggcagcctgctcgtgatcgacacg
cccggcgctcgcatcgacgtgcggctcaacgcgctcggcgagcacaacgcgcgcaacgcg
ctcgccgcgacggcggcggcgctcgcggccggcgtgccgctcgcggcgatcaaggccggg
ctcgaggcgttcgcgccggtgaaagggcggctgcaggtggcgcgcgcggcggcgggctcg
ctcgcgggcgcgacggtgatcgacgacacctacaacgcgaaccccgattcgatgcgcgcc
gcgatcgacgtgctcgccgcgcaatcggcgccacgcgtgctcgtgatcggcgagatgggc
gaagtcggcgacgaagggccggcgttccaccgcgagatcggcgcgtacgcgcgcgagcgc
ggcatcgacgcgctcttcgcgctcggcgcggcgacgcggcccgcgtgcgacgcatacggc
gcgggcgcgcggcatttcgacgacgcggccgcactcgtcgccgcgctgctcgccgcgaac
ttcggcgcgcacgcgacgctgctcgtgaagggctcgcggttcatgaagatggagcgcgtg
gtcgacgcgctcgcgaacgaaaccgcgtcgggcgcagcgcccgacgcacactga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (25)   

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