KEGG   Bos taurus (cow): 100125224
Entry
100125224         CDS       T01008                                 
Symbol
PIP5K1A
Name
(RefSeq) phosphatidylinositol 4-phosphate 5-kinase type-1 alpha
  KO
K00889  1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
Organism
bta  Bos taurus (cow)
Pathway
bta00562  Inositol phosphate metabolism
bta01100  Metabolic pathways
bta04070  Phosphatidylinositol signaling system
bta04072  Phospholipase D signaling pathway
bta04144  Endocytosis
bta04510  Focal adhesion
bta04666  Fc gamma R-mediated phagocytosis
bta04810  Regulation of actin cytoskeleton
bta05135  Yersinia infection
bta05231  Choline metabolism in cancer
Module
bta_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:bta00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100125224 (PIP5K1A)
 09130 Environmental Information Processing
  09132 Signal transduction
   04070 Phosphatidylinositol signaling system
    100125224 (PIP5K1A)
   04072 Phospholipase D signaling pathway
    100125224 (PIP5K1A)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    100125224 (PIP5K1A)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100125224 (PIP5K1A)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100125224 (PIP5K1A)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    100125224 (PIP5K1A)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    100125224 (PIP5K1A)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    100125224 (PIP5K1A)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:bta04131]
    100125224 (PIP5K1A)
Enzymes [BR:bta01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.68  1-phosphatidylinositol-4-phosphate 5-kinase
     100125224 (PIP5K1A)
Membrane trafficking [BR:bta04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    100125224 (PIP5K1A)
 Endocytosis
  Clathrin-mediated endocytosis
   LDLR adaptor proteins
    100125224 (PIP5K1A)
 Endosome - Golgi transport
  Others
   Others
    100125224 (PIP5K1A)
SSDB
Motif
Pfam: PIP5K
Other DBs
NCBI-GeneID: 100125224
NCBI-ProteinID: NP_001096579
BGD-bta: BT24184
Ensembl: ENSBTAG00000006099
VGNC: 55656
UniProt: A8E4M7 A6QLC5
Position
3:complement(19572071..19611272)
AA seq 549 aa
MASASSGPSAVGFSSADSSVPPCTSASASGIKRPTASEVPYSSGMSMKKIGHRGVDSSGE
TTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHY
NDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELCNSGASGSLFYVSSDDEFIIK
TVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKM
HIKYDLKGSTYKRRASQKEREKPLPTLKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLV
LQSFKIMDYSLLVSIHNIDHAQREPLGSEAQYSADTRRPAPQKALYSTAMESIQGEARRG
GTMETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFIKKLEHSWKALVHDGDTVSVHRP
SFYAERFQRFMCTTVFKKIPLKSSPSKKFRSGSSFSRRAGPSGNSCVTYQPSVSGEHKAQ
VTTKAEVEPGVHLGRPDVLPQTPPLEKISEVSTIPDPYFSPVVGETLQTLTTSSTLLEKH
EVPESEFIH
NT seq 1650 nt   +upstreamnt  +downstreamnt
atggcgtctgcctcctctgggccgtcggcggtagggttttcatccgcggattccagcgtc
cctccctgcacctcggcctcagcatctggaatcaagagacccacggcatctgaggtgcct
tattcctctggcatgtccatgaagaaaataggtcaccgaggtgttgattcctcaggagag
acaacatataaaaagacaacctcatcagccttaaaaggtgccatccagttaggcattact
cacactgtgggaagcctgagtaccaaaccagagcgagatgtcctcatgcaagacttctac
gtggtggagagtatcttcttcccgagtgaagggagcaacctgacccctgctcatcactac
aatgactttcggttcaagacctacgcacctgttgccttccgatactttcgggagttattt
ggtatccggcctgatgattacttgtactccctctgcaatgaaccactgattgaactctgc
aactctggggccagtggttccctcttctacgtgtccagcgatgacgaattcatcataaaa
acagtccagcacaaagaggcggagtttctacagaagctgcttccaggatactacatgaac
ctcaaccaaaaccctcggactttgctgcctaagttctatggactgtactgtgtgcaggca
ggtggtaagaatattcgaattgtcgtgatgaacaatctcttaccacggtcagtcaagatg
catatcaagtatgacctcaagggctcaacatacaaaaggcgagcttcccaaaaagagcga
gagaaacctcttcctacccttaaagacctggacttcttacaagacatccctgatggtctc
tttttggatgctgatatgtacaatgctctatgcaagaccctgcagcgtgactgtttggtt
ctgcagagcttcaagataatggactatagcctcctggtgtcaatccataacatagatcat
gcacaacgagagcctttaggcagtgaagcacaatattcagctgacactcgcagaccagcc
ccgcaaaaggctctctattccacagccatggaatctatccagggcgaggctcgacgaggt
ggcaccatggagaccgatgaccatatgggtggcatcccggcccggaatagtaaaggggaa
aggctgctgctttatatcgggatcattgacattctgcagtcttacaggtttattaagaag
ttggagcattcttggaaagctctggtacatgatggggacaccgtatcagtgcatcgcccc
agcttctacgctgaacggttccagcgtttcatgtgcactacagtttttaagaagatcccc
ttgaagtcctctccttccaaaaagtttcggtctggctcatctttctctcggcgagcaggc
cccagcggcaactcctgcgtaacttaccagccatcggtctctggggaacacaaggcacaa
gtgacaacaaaggcggaagtggagccaggcgtccacttgggtcgtcctgatgttttacct
cagactccacctttggagaaaatcagtgaggtctcgactattcctgacccctatttctca
cctgtagttggagagactttgcaaacgctaactacaagttcaaccctcttggaaaaacat
gaagttccagagtcagagttcatccattga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (11)   
   KEGG PATHWAY (10)   
   KEGG MODULE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   BGD-BTA (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (13)   
   UniProt (2)   
   RefSeq(pep) (11)   
DNA sequence (15)   
   RefSeq(nuc) (11)   
   GenBank (2)   
   EMBL (2)   
Protein domain (1)   
   Pfam (1)   
All databases (63)   

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