KEGG   Bos taurus (cow): 280762
Entry
280762            CDS       T01008                                 
Symbol
DDC
Name
(RefSeq) aromatic-L-amino-acid decarboxylase
  KO
K01593  aromatic-L-amino-acid/L-tryptophan decarboxylase [EC:4.1.1.28 4.1.1.105]
Organism
bta  Bos taurus (cow)
Pathway
bta00350  Tyrosine metabolism
bta00360  Phenylalanine metabolism
bta00380  Tryptophan metabolism
bta01100  Metabolic pathways
bta04726  Serotonergic synapse
bta04728  Dopaminergic synapse
bta05030  Cocaine addiction
bta05031  Amphetamine addiction
bta05034  Alcoholism
Module
bta_M00037  Melatonin biosynthesis, animals, tryptophan => serotonin => melatonin
bta_M00042  Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:bta00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00350 Tyrosine metabolism
    280762 (DDC)
   00360 Phenylalanine metabolism
    280762 (DDC)
   00380 Tryptophan metabolism
    280762 (DDC)
 09150 Organismal Systems
  09156 Nervous system
   04728 Dopaminergic synapse
    280762 (DDC)
   04726 Serotonergic synapse
    280762 (DDC)
 09160 Human Diseases
  09165 Substance dependence
   05030 Cocaine addiction
    280762 (DDC)
   05031 Amphetamine addiction
    280762 (DDC)
   05034 Alcoholism
    280762 (DDC)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:bta04147]
    280762 (DDC)
Enzymes [BR:bta01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.28  aromatic-L-amino-acid decarboxylase
     280762 (DDC)
    4.1.1.105  L-tryptophan decarboxylase
     280762 (DDC)
Exosome [BR:bta04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   280762 (DDC)
SSDB
Motif
Pfam: Pyridoxal_deC Beta_elim_lyase
Other DBs
NCBI-GeneID: 280762
NCBI-ProteinID: NP_776332
BGD-bta: BT28956
Ensembl: ENSBTAG00000020869
VGNC: 55748
UniProt: P27718
Position
4:5335520..5441303
AA seq 487 aa
MNASEFRRRGKEMVDYVADYLEGIEGRQVFPDVDPGYLRPLIPTTAPQEPETFEAIIEDI
EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD
WLGKMLQLPEAFLAGEAGEGGGVIQGTASEATLVALLAARTKVTRHLQARAPELTQAAIM
EKLVAYASDQAHSSVEKAGLIGGVRLKAIPSDGKFAMRASRCRRLERDKAAGLIPSCFVV
ATLGTTSCCSFDNLLEVGPICHKEGLWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN
PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPVYLRHSHQDSGLITDYRHWQLPLGRRFRSL
KMWFVFRMYGVKGLQAYIRKHVQLSHAFEALVRQDTRFEICAEVILGLVCFRLKGSNKLN
EALLESINSAKKIHLVPCSLRDRFVLRFAICSRTVELAHVQLAWEHIQEMAATVLRAQGE
EKAEIKN
NT seq 1464 nt   +upstreamnt  +downstreamnt
atgaatgcaagcgagttccgcaggcgggggaaggagatggtggattacgtggctgactac
ttggagggcattgaagggcgccaggtgttccctgacgtggatccaggctacctgcgcccc
ctgatccccaccaccgccccgcaggagccagagacatttgaggccatcatcgaggacatc
gagaagatcatcatgccgggggtgacccactggcacagtccctacttcttcgcctacttc
cccacggccagttcgtacccggccatgctcgcggacatgctgtgtggggccatcggctgc
atcggcttctcctgggctgccagcccggcgtgcacagagctcgagacggtgatgatggac
tggctggggaagatgctgcagctgccagaggcgtttctggctggagaagctggagaaggc
ggcggggtgatccagggaactgccagtgaagctacccttgtggccctgctggccgctcgg
accaaagtgacccgacacctgcaggctcgtgccccagagctgacgcaggctgccatcatg
gagaagttggtggcctacgcatctgaccaggcacactcctccgtggaaaaagccggctta
attggcggagtgagattaaaagccatcccttccgatggcaagtttgccatgcgagcttcg
cgctgcaggaggctggagagagacaaggcagccggcctgattccttcttgcttcgtggtg
gctacactggggaccacgtcctgctgctcctttgacaacctcttagaagtggggcccatt
tgtcacaaggagggcttgtggctgcacgtggacgccgcctacgcaggcagtgccttcatc
tgccctgagttccggcatcttctgaatggcgtggagtttgcagattcatttaactttaat
ccccacaaatggctcttggtgaattttgactgctctgccatgtgggtgaaaaagaggaca
gacctgaccggagccttcaggctggacccagtctatctgaggcacagccaccaggactca
gggcttatcactgactacaggcactggcagctgccactgggccggaggttccgctctttg
aagatgtggtttgtttttaggatgtacggagtcaagggactgcaggcctatatccgcaag
catgtccagctgtcccatgcattcgaggcattggtgcgccaggacacccgctttgaaatc
tgtgcagaagtcattctgggactggtctgtttccggctaaagggttccaacaaactgaac
gaagctcttctggaaagcataaacagtgccaaaaaaatccacttggtcccttgttccctg
agagaccggttcgtgctgcgcttcgccatctgctcacgcacagtggagctggcccacgta
cagctggcctgggagcacatccaggagatggcggccacagtgttaagagcacagggggag
gaaaaggcagagatcaaaaattga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (12)   
   KEGG PATHWAY (9)   
   KEGG MODULE (3)   
Chemical substance (13)   
   KEGG COMPOUND (13)   
Chemical reaction (8)   
   KEGG ENZYME (2)   
   KEGG REACTION (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   BGD-BTA (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (10)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (8)   
DNA sequence (14)   
   RefSeq(nuc) (8)   
   GenBank (3)   
   EMBL (3)   
Protein domain (2)   
   Pfam (2)   
All databases (75)   

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