KEGG   Bos taurus (cow): 280829
Entry
280829            CDS       T01008                                 
Symbol
INS
Name
(RefSeq) insulin preproprotein
  KO
K04526  insulin
Organism
bta  Bos taurus (cow)
Pathway
bta04010  MAPK signaling pathway
bta04014  Ras signaling pathway
bta04015  Rap1 signaling pathway
bta04022  cGMP-PKG signaling pathway
bta04066  HIF-1 signaling pathway
bta04068  FoxO signaling pathway
bta04072  Phospholipase D signaling pathway
bta04114  Oocyte meiosis
bta04140  Autophagy - animal
bta04150  mTOR signaling pathway
bta04151  PI3K-Akt signaling pathway
bta04152  AMPK signaling pathway
bta04211  Longevity regulating pathway
bta04213  Longevity regulating pathway - multiple species
bta04810  Regulation of actin cytoskeleton
bta04910  Insulin signaling pathway
bta04911  Insulin secretion
bta04913  Ovarian steroidogenesis
bta04914  Progesterone-mediated oocyte maturation
bta04917  Prolactin signaling pathway
bta04923  Regulation of lipolysis in adipocytes
bta04930  Type II diabetes mellitus
bta04931  Insulin resistance
bta04932  Non-alcoholic fatty liver disease
bta04940  Type I diabetes mellitus
bta04950  Maturity onset diabetes of the young
bta04960  Aldosterone-regulated sodium reabsorption
bta05010  Alzheimer disease
bta05215  Prostate cancer
bta05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:bta00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    280829 (INS)
   04014 Ras signaling pathway
    280829 (INS)
   04015 Rap1 signaling pathway
    280829 (INS)
   04066 HIF-1 signaling pathway
    280829 (INS)
   04068 FoxO signaling pathway
    280829 (INS)
   04072 Phospholipase D signaling pathway
    280829 (INS)
   04022 cGMP-PKG signaling pathway
    280829 (INS)
   04151 PI3K-Akt signaling pathway
    280829 (INS)
   04152 AMPK signaling pathway
    280829 (INS)
   04150 mTOR signaling pathway
    280829 (INS)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    280829 (INS)
  09143 Cell growth and death
   04114 Oocyte meiosis
    280829 (INS)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    280829 (INS)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    280829 (INS)
   04910 Insulin signaling pathway
    280829 (INS)
   04923 Regulation of lipolysis in adipocytes
    280829 (INS)
   04913 Ovarian steroidogenesis
    280829 (INS)
   04914 Progesterone-mediated oocyte maturation
    280829 (INS)
   04917 Prolactin signaling pathway
    280829 (INS)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    280829 (INS)
  09149 Aging
   04211 Longevity regulating pathway
    280829 (INS)
   04213 Longevity regulating pathway - multiple species
    280829 (INS)
 09160 Human Diseases
  09162 Cancer: specific types
   05215 Prostate cancer
    280829 (INS)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    280829 (INS)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    280829 (INS)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    280829 (INS)
   04940 Type I diabetes mellitus
    280829 (INS)
   04950 Maturity onset diabetes of the young
    280829 (INS)
   04932 Non-alcoholic fatty liver disease
    280829 (INS)
   04931 Insulin resistance
    280829 (INS)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:bta04052]
    280829 (INS)
Cytokines and neuropeptides [BR:bta04052]
 Neuropeptides
  Neuropeptides (Unclassified)
   280829 (INS)
SSDB
Motif
Pfam: Insulin Ins_beta
Other DBs
NCBI-GeneID: 280829
NCBI-ProteinID: NP_001172055
BGD-bta: BT10074
Ensembl: ENSBTAG00000013003
VGNC: 56268
UniProt: A5PJB2
Position
29:49393375..49394536
AA seq 105 aa
MALWTRLAPLLALLALWAPAPARAFVNQHLCGSHLVEALYLVCGERGFFYTPKARREVEG
PQVGALELAGGPGAGGLEGPPQKRGIVEQCCASVCSLYQLENYCN
NT seq 318 nt   +upstreamnt  +downstreamnt
atggccctgtggacacgcctggcgcccctgctggccctgctggcgctctgggcccccgcc
ccggcccgcgccttcgtcaaccagcatctgtgtggctcccacctggtggaggcgctgtac
ctggtgtgcggagagcgcggcttcttctacacgcccaaggcccgccgggaggtggagggc
ccccaggtgggggcgctggagctggccggaggcccgggcgcgggcggcctggaggggccc
ccgcagaagcgtggcatcgtggagcagtgctgtgccagcgtctgctcgctctaccagctg
gagaactactgtaactag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (30)   
   KEGG PATHWAY (30)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   BGD-BTA (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (12)   
   RefSeq(nuc) (2)   
   GenBank (5)   
   EMBL (5)   
Protein domain (2)   
   Pfam (2)   
All databases (59)   

Download RDF
DBGET integrated database retrieval system