KEGG   Bos taurus (cow): 281181
Entry
281181            CDS       T01008                                 
Symbol
GAPDH
Name
(RefSeq) glyceraldehyde-3-phosphate dehydrogenase
  KO
K00134  glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
Organism
bta  Bos taurus (cow)
Pathway
bta00010  Glycolysis / Gluconeogenesis
bta01100  Metabolic pathways
bta01200  Carbon metabolism
bta01230  Biosynthesis of amino acids
bta04066  HIF-1 signaling pathway
bta05010  Alzheimer disease
bta05132  Salmonella infection
bta05415  Diabetic cardiomyopathy
Module
bta_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
bta_M00002  Glycolysis, core module involving three-carbon compounds
bta_M00003  Gluconeogenesis, oxaloacetate => fructose-6P
Brite
KEGG Orthology (KO) [BR:bta00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    281181 (GAPDH)
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    281181 (GAPDH)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    281181 (GAPDH)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    281181 (GAPDH)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    281181 (GAPDH)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:bta04131]
    281181 (GAPDH)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:bta04147]
    281181 (GAPDH)
Enzymes [BR:bta01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.12  glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)
     281181 (GAPDH)
Membrane trafficking [BR:bta04131]
 Autophagy
  Chaperone mediated autophagy (CMA)
   Selective cargos
    281181 (GAPDH)
Exosome [BR:bta04147]
 Exosomal proteins
  Proteins found in most exosomes
   281181 (GAPDH)
SSDB
Motif
Pfam: Gp_dh_C Gp_dh_N LptD_N
Other DBs
NCBI-GeneID: 281181
NCBI-ProteinID: NP_001029206
BGD-bta: BT11420
Ensembl: ENSBTAG00000014731
VGNC: 97273
UniProt: P10096
Structure
Position
5:complement(103870384..103874667)
AA seq 333 aa
MVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLHYMVYMFQYDSTHGKFNGTVKA
ENGKLVINGKAITIFQERDPANIKWGDAGAEYVVESTGVFTTMEKAGAHLKGGAKRVIIS
APSADAPMFVMGVNHEKYNNTLKIVSNASCTTNCLAPLAKVIHDHFGIVEGLMTTVHAIT
ATQKTVDGPSGKLWRDGRGAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSV
VDLTCRLEKPAKYDEIKKVVKQASEGPLKGILGYTEDQVVSCDFNSDTHSSTFDAGAGIA
LNDHFVKLISWYDNEFGYSNRVVDLMVHMASKE
NT seq 1002 nt   +upstreamnt  +downstreamnt
atggtgaaggtcggagtgaacggattcggccgcatcgggcgcctggtcaccagggctgct
tttaattctggcaaagtggacatcgtcgccatcaatgaccccttcattgaccttcactac
atggtctacatgttccagtatgattccacccacggcaagttcaacggcacagtcaaggca
gagaacgggaagctcgtcatcaatggaaaggccatcaccatcttccaggagcgagatcct
gccaacatcaagtggggtgatgctggtgctgagtatgtggtggagtccactggggtcttc
actaccatggagaaggctggggctcacttgaagggtggcgccaagagggtcatcatctct
gcaccttctgccgatgcccccatgtttgtgatgggcgtgaaccacgagaagtataacaac
accctcaagattgtcagcaatgcctcctgcaccaccaactgcttggcccccctggccaag
gtcatccatgaccactttggcatcgtggagggacttatgaccactgtccacgccatcact
gccacccagaagactgtggatggcccctccgggaagctgtggcgtgacggccgaggggct
gcccagaatatcatccctgcttctactggcgctgccaaggccgtgggcaaggtcatccct
gagctcaacgggaagctcactggcatggccttccgcgtccccactcccaacgtgtctgtt
gtggatctgacctgccgcctggagaaacctgccaagtatgatgagatcaagaaggtggtg
aagcaggcgtcagagggccctctcaagggcattctaggctacactgaggaccaggttgtc
tcctgcgacttcaacagcgacactcactcttctaccttcgatgctggggctggcattgcc
ctcaacgaccactttgtcaagctcatttcctggtacgacaatgaatttggctacagcaac
agggtggtggacctcatggtccacatggcctccaaggagtaa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (14)   
   KEGG PATHWAY (8)   
   KEGG MODULE (6)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   BGD-BTA (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (21)   
   RefSeq(nuc) (1)   
   GenBank (10)   
   EMBL (10)   
3D Structure (3)   
   PDB (3)   
Protein domain (3)   
   Pfam (3)   
All databases (74)   

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