KEGG   Bos taurus (cow): 282004
Entry
282004            CDS       T01008                                 
Symbol
PRKG1
Name
(RefSeq) cGMP-dependent protein kinase 1
  KO
K07376  cGMP-dependent protein kinase 1 [EC:2.7.11.12]
Organism
bta  Bos taurus (cow)
Pathway
bta04022  cGMP-PKG signaling pathway
bta04081  Hormone signaling
bta04270  Vascular smooth muscle contraction
bta04540  Gap junction
bta04611  Platelet activation
bta04713  Circadian entrainment
bta04714  Thermogenesis
bta04730  Long-term depression
bta04740  Olfactory transduction
bta04923  Regulation of lipolysis in adipocytes
bta04970  Salivary secretion
Brite
KEGG Orthology (KO) [BR:bta00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04022 cGMP-PKG signaling pathway
    282004 (PRKG1)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    282004 (PRKG1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    282004 (PRKG1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    282004 (PRKG1)
  09152 Endocrine system
   04923 Regulation of lipolysis in adipocytes
    282004 (PRKG1)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    282004 (PRKG1)
  09154 Digestive system
   04970 Salivary secretion
    282004 (PRKG1)
  09156 Nervous system
   04730 Long-term depression
    282004 (PRKG1)
  09157 Sensory system
   04740 Olfactory transduction
    282004 (PRKG1)
  09159 Environmental adaptation
   04713 Circadian entrainment
    282004 (PRKG1)
   04714 Thermogenesis
    282004 (PRKG1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bta01001]
    282004 (PRKG1)
Enzymes [BR:bta01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.12  cGMP-dependent protein kinase
     282004 (PRKG1)
Protein kinases [BR:bta01001]
 Serine/threonine kinases: AGC group
  PKG family
   282004 (PRKG1)
SSDB
Motif
Pfam: Pkinase cNMP_binding PK_Tyr_Ser-Thr PKcGMP_CC Kinase-like Wtap Pkinase_C Med4 APH Med28 DUF7201
Other DBs
NCBI-GeneID: 282004
NCBI-ProteinID: NP_776861
BGD-bta: BT19454
Ensembl: ENSBTAG00000018404
VGNC: 33340
UniProt: P00516
Structure
Position
26:complement(6895298..8313728)
AA seq 671 aa
MSELEEDFAKILMLKEERIKELEKRLSEKEEEIQELKRKLHKCQSVLPVPSTHIGPRTTR
AQGISAEPQTYRSFHDLRQAFRKFTKSERSKDLIKEAILDNDFMKNLELSQIQEIVDCMY
PVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTRTAT
VKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVLEET
HYENGEYIIRQGARGDTFFIISKGKVNVTREDSPNEDPVFLRTLGKGDWFGEKALQGEDV
RTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAAFFANLKLSDF
NIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSDF
IVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGI
IYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISAD
YWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDNPS
ERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDNDEPP
PDDNSGWDIDF
NT seq 2016 nt   +upstreamnt  +downstreamnt
atgagcgagctggaggaagactttgccaagattctcatgctcaaggaggagaggatcaaa
gagctggagaagcggctgtcagagaaggaggaagaaatccaggagctgaagaggaaactc
cataaatgccagtcagtgctgcccgtgccctcgacccacatcggcccccggaccacccgg
gcacagggcatctcggccgagccgcagacctacaggtccttccacgacctccgacaggca
ttccggaagttcaccaaatccgaaaggtccaaggatctcataaaggaggccatccttgac
aatgactttatgaagaacttggagctgtcacagatccaagagattgtggattgtatgtac
ccagtggagtacggcaaagacagctgcatcatcaaagaaggagatgtggggtcactggtg
tatgtcatggaagatggtaaggttgaagttacaaaagaaggcgtgaagctgtgcacaatg
ggtcctggtaaagtgtttggagagttggctatcctttacaactgtacccggacggcgacc
gtcaaaactcttgtaaatgtgaaactctgggccattgatcgacaatgttttcagacgata
atgatgaggacaggacttatcaagcataccgagtatatggaatttttaaaaagcgttcca
acattccagagccttcctgaagagatcctcagtaagcttgctgacgtccttgaagagacc
cactatgaaaatggggaatatatcatcaggcaaggtgcaagaggggacaccttctttatc
atcagtaaaggaaaggttaatgtcactcgtgaagactcgcccaatgaagacccagtcttt
cttagaaccttaggaaaaggagattggtttggagagaaagccttgcagggggaagatgtg
agaacagcgaatgtaattgcggcagaagctgtaacctgccttgtgatcgacagagactct
ttcaaacatttgattggaggattagatgatgtttctaataaagcatatgaagatgcagaa
gctaaggcaaaatatgaagctgaagctgctttcttcgccaacctgaagctgtctgatttc
aacatcattgacacccttggagttggaggtttcggacgcgtagaactggtccagttaaaa
agtgaagaatccaaaacctttgcaatgaagattctcaagaaacggcacatcgtggataca
agacagcaggaacacatccgctcggagaagcagatcatgcagggggcccattcggacttc
atagtgagattatacagaacatttaaggacagcaaatatttgtatatgttgatggaagct
tgcctaggtggagagctctggaccattctcagggatcgggggtcatttgaagattctaca
accagattttatacagcatgtgtggtagaagcttttgcctatctgcattccaaaggaatc
atttacagggacctcaagcctgaaaatctcatcctagatcaccgaggttatgccaaactg
gttgattttggctttgcaaagaaaataggatttggaaagaaaacatggactttttgtggg
actccagaatatgtagccccagagatcatcctgaacaaaggccatgacatttcagccgac
tattggtcactgggaatcctcatgtatgagcttctgactggcagcccacctttctcaggc
ccagatcctatgaaaacctataacatcatattgagggggattgacatgatagagtttcca
aagaagattgccaaaaatgctgctaatttaattaaaaaactatgcagggataatccatca
gaaagattagggaatttgaaaaacggagtgaaagacattcaaaagcacaaatggtttgag
ggctttaattgggaaggcttaagaaaaggcaccttgacacctcctataataccaagtgtt
gcatcacccacagacacaagcaattttgacagtttccctgaggacaatgatgaaccgcca
cctgatgacaactcaggatgggacatagacttctaa

  All links  
Gene (24)   
   RefGene (18)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   BGD-BTA (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (11)   
   RefSeq(nuc) (3)   
   GenBank (4)   
   EMBL (4)   
3D Structure (1)   
   PDB (1)   
Protein domain (11)   
   Pfam (11)   
All databases (52)   

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