KEGG   Bos taurus (cow): 286772
Entry
286772            CDS       T01008                                 
Symbol
NPC1
Name
(RefSeq) NPC intracellular cholesterol transporter 1 precursor
  KO
K12385  Niemann-Pick C1 protein
Organism
bta  Bos taurus (cow)
Pathway
bta03265  Virion - Ebolavirus and Lyssavirus
bta04142  Lysosome
bta04979  Cholesterol metabolism
Brite
KEGG Orthology (KO) [BR:bta00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03265 Virion - Ebolavirus and Lyssavirus
    286772 (NPC1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04142 Lysosome
    286772 (NPC1)
 09150 Organismal Systems
  09154 Digestive system
   04979 Cholesterol metabolism
    286772 (NPC1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:bta02000]
    286772 (NPC1)
Transporters [BR:bta02000]
 Solute carrier family (SLC)
  SLC65: NPC-type cholesterol transporter
   286772 (NPC1)
SSDB
Motif
Pfam: Patched NPC1_N Sterol-sensing MMPL ACR_tran TMEM51
Other DBs
NCBI-GeneID: 286772
NCBI-ProteinID: NP_777183
BGD-bta: BT11606
Ensembl: ENSBTAG00000015195
VGNC: 32194
UniProt: Q9GLC9
Position
24:33058694..33105394
AA seq 1277 aa
MSVLGPAFGLLLLLFCPAQVFSQSCIWYGECGIASGDKRYNCRYSGPPEPLPQDGYDLVQ
ELCPGFFFGNVSLCCDVQQLHTLKDNLQLPLQFLSRCPSCFYNLVNLFCELTCSPRQSQF
LNVTATEDYVDPATNQTKTNVKELQYYVGESFANAMYNSCRDVEAPSSNEKALGLLCGRE
ASACNATNWIEYMFNKDNGQAPFTITPVFSDLPTHGMEPMNNATKGCDESVDEVTGPCSC
QDCSAVCGPKPQPPPPPVPWKILGLDAMYVIMWSTYMAFLLVFFGAFFAVWCYRKRYFVS
EFTPIDGNIPFSINASDKGGPTCCDPLGAAFEAHLRRLFEWWGSFCVRHPGCVVFFSVAF
IAACSSGLVFIQVTTDPVDLWSAPGSQARLEKEYFDTHFGPFFRTEQLIIRAPHTPPHIY
EPYPSGADVPFGPPLAVNILHQVLDLQTAIESITASYNNETVTLRDICVAPLSPYNQNCT
ILSVLNYFQNSHSVLDHQVGDDFFVYADYHTHFLYWVRAPASLNDTSLLHDPCLGTFGGP
VFPWLVLGGYDDQNYNNATALVITFPVNNYYNDTEKLQRAQAWEKEFINFVQNYENPNLT
ISFKAERSIEDELNRESNSDVFTVLISYGVMFLYISIALGHIKSCRRLLVDSKILLGIAG
VLIVLSPVACSLGFFSYWGSPLTLIVIEVIPFLVLAVGVDNIFILVQTYQIDERLQGETL
DQQVGRVLGEVAPSMFLSSFAETVAFFLGGLSVMPAVHTFSLFAGMAVLIDFLLQITCFV
SLLGLDIKRQEKNQLDVLCCVGGAADDAGIQASESCLFRFFRNSYAPLLLKDWMRPLVVA
VFVGVLSFSIAVLNKVEIGLDQSLSMPDDSYVTDYFQSLNQYLHAGPPVYFVLEEGHDYT
STKGQNMVCGGLGCNNDSLVQQVFTAAQLDSYTRIGFAPSSWIDDYFDWVKPQSSCCRIY
NSTEQFCNASVVNPTCVRCRPLTPEGKQRPQGADFMRFLPMFLSDNPNPKCGKGGHAAYS
AAVNILDNGTRVGATYFMTYHTVLQTSADFIDAMEKARLIASNITRTMNQQGGDHRVFPY
SVFYVFYEQYLTMIDDTIFNLSVSLGAIFLVAVVLLGCELWSAVIMCATIAMILVNMFGV
MWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSTKGSRVERAEEALSHMGSSVFSG
ITLTKFGGIIVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGPSINKAKSL
TTQQRYRGTEREQLLNF
NT seq 3834 nt   +upstreamnt  +downstreamnt
atgagcgtgctcggcccagccttcggcctcctcctgctgctgttctgcccggcgcaggta
ttttcacagtcctgcatttggtatggagagtgtggaattgcatctggagataagagatac
aactgcagatattctgggccaccagagccattgccacaggatggctatgacctagtgcag
gaactctgtccagggttcttctttggcaatgtcagtctttgctgtgatgtccagcagctt
cacacactgaaggacaacctgcagctgcctctgcagtttctgtccagatgtccatcctgt
ttttataacctagtgaacctgttttgtgagctgacatgtagccctcgacaaagtcagttt
ctgaacgttacagcaactgaagattatgttgatcctgctacaaaccagacgaaaacaaat
gtaaaagaattacagtactatgttggagagagttttgccaatgccatgtacaattcctgc
cgggatgtggaggccccctcgagcaacgagaaggccctggggctgctgtgcgggcgtgag
gccagcgcctgcaatgctactaactggatcgagtacatgttcaacaaggacaatggccag
gcgcccttcaccatcacccccgtcttttcagatcttccgacgcatgggatggagcccatg
aacaatgccaccaagggctgtgacgagtcggtggacgaggtcacggggccgtgcagctgc
caggactgctcggccgtctgcggccccaagccccagcccccaccccctcccgttccctgg
aaaatcctgggtctggacgccatgtatgtcatcatgtggagcacctacatggctttcctg
ctcgtgttctttggagcgttctttgctgtgtggtgctacagaaaacggtattttgtctct
gagtttacccccattgatggcaatatacctttctctataaacgccagtgacaaagggggg
ccaacctgctgtgaccctttgggtgccgccttcgaggctcatctgcggcggctcttcgaa
tggtggggctccttctgcgtgaggcaccccggctgtgtcgtgttcttctccgtggccttc
atcgccgcctgttcctcaggcctggtgttcatccaggtcacaaccgacccggtggacctc
tggtcggcccccggcagccaggcgcgcctggagaaggagtactttgacacgcacttcggg
cccttcttccgcaccgagcagctcatcatcagggccccccacaccccgccgcacatatac
gagccctacccctcgggagccgacgtgccctttgggcctccccttgctgtaaacattctg
caccaggtccttgacttacaaaccgccatcgagagcatcactgcttcttacaacaacgag
actgtgaccctgcgggacatttgcgtggcgcccctctcgccatacaaccagaactgcacc
atcctgagtgtgctgaactacttccagaacagccactctgtgctggaccatcaagtcggg
gatgacttcttcgtgtatgcagattaccacacgcacttcctctactgggtccgggctcct
gcttccctgaatgacaccagtttgctccacgatccttgcctggggacgtttggtggccca
gtgttcccatggcttgtgcttggaggctacgatgatcaaaactacaataacgccacagcc
cttgtgatcacctttcctgtcaataattactataacgatacagagaagctccagagggcc
caggcctgggaaaaagagttcattaattttgtgcaaaactacgagaatccaaatctgacc
atttcttttaaggctgaacgaagcattgaagatgaactaaaccgtgaaagtaacagtgat
gtgttcactgttctgatcagctatggcgtcatgtttttatatatttccatagccttgggg
catatcaaaagctgtcgcaggcttctggtggattcgaaaatactcctgggcattgccggt
gtcctgattgtgttgagcccagtggcctgctccttgggcttcttcagctactggggctcc
cccctcaccctcattgtgatagaagtcatcccattcctcgtgctggctgtgggggtggac
aacatcttcatcctggtccagacctaccagatagatgaacgtcttcaaggggaaaccctc
gaccaacaggtgggccgggtcctgggagaagtggctcccagcatgttcctctcatccttc
gcagagacggtagcgtttttcttaggaggcctgtctgtgatgccggccgtgcacacgttc
tctctcttcgcgggcatggcagtcctcatcgacttcctcctgcagatcacctgcttcgtg
agcctcctgggtttggacattaagcggcaagagaagaaccagctggacgttctctgctgt
gtcgggggggcggcagacgacgcgggcatccaggcctccgagagctgcttgttccgcttc
ttcagaaactcctacgcgccgcttctgctcaaggactggatgcggcccctcgtggtggca
gtatttgtgggtgtgctgtcgttcagtatcgcagtcctgaacaaagtagagatcggattg
gatcagtctctttcaatgccggatgactcctacgtgacggattacttccagtccctgaat
cagtacctgcacgcaggcccacctgtgtacttcgtgctggaggagggccacgactacacg
tccacgaaggggcagaacatggtgtgcgggggcctcggctgcaacaacgactcgctggtg
cagcaggtcttcacggccgcccagctggacagctacacccggataggctttgccccgtcg
tcctggattgacgattactttgactgggtcaagcctcaatcttcttgctgtcgcatctac
aacagcacggagcagttctgcaatgcatcggtggtcaaccctacctgtgtccgctgccgg
ccgctgactccagagggcaagcagagacctcagggcgcagacttcatgaggttcctgccc
atgttcctctccgacaacccgaaccccaagtgtggcaaagggggacacgctgcctacagc
gcagccgtcaacatcctggacaacggcacgagggtgggagccacgtacttcatgacctac
cacacggtgctgcagacctcggctgacttcatcgatgccatggagaaggcccgcctcatc
gccagcaacatcaccaggaccatgaaccagcaggggggtgatcaccgggtgttcccatac
agcgtgttctatgtcttctatgagcagtacctgaccatgattgacgacaccatcttcaac
ctcagcgtgtccctgggcgccatcttcctggtggccgtggtcctcttgggctgtgagctg
tggtctgcggtcatcatgtgcgccaccatcgccatgatcttggtcaacatgtttggtgtc
atgtggctgtggggcatcagcctgaacgcggtttctctggtcaacctggtcatgagctgt
ggcatctccgtggagttctgtagccacatcacgagggccttcacggtgagcacgaagggc
agccgcgtagagcgggcggaggaggcgctctcccacatgggcagctctgtattcagtgga
atcacactaacgaaatttggaggcattatcgtgttggcttttgccaaatctcaaattttc
cagatattttacttcaggatgtatttagctatggtcttactgggagccactcatggacta
atattcctccctgtcctactcagttacataggcccgtcaataaataaagccaaaagtttg
accacgcagcagcgatacagaggtacagaacgagaacagctcctcaatttctag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (30)   
   KEGG ORTHOLOGY (1)   
   RefGene (23)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   BGD-BTA (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (5)   
   RefSeq(nuc) (1)   
   GenBank (2)   
   EMBL (2)   
Protein domain (6)   
   Pfam (6)   
All databases (49)   

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