KEGG   Bos taurus (cow): 535293
Entry
535293            CDS       T01008                                 
Symbol
EPHX1
Name
(RefSeq) epoxide hydrolase 1 precursor
  KO
K01253  microsomal epoxide hydrolase [EC:3.3.2.9]
Organism
bta  Bos taurus (cow)
Pathway
bta00980  Metabolism of xenobiotics by cytochrome P450
bta04976  Bile secretion
bta05204  Chemical carcinogenesis - DNA adducts
bta05207  Chemical carcinogenesis - receptor activation
bta05208  Chemical carcinogenesis - reactive oxygen species
Brite
KEGG Orthology (KO) [BR:bta00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    535293 (EPHX1)
 09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    535293 (EPHX1)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    535293 (EPHX1)
   05207 Chemical carcinogenesis - receptor activation
    535293 (EPHX1)
   05208 Chemical carcinogenesis - reactive oxygen species
    535293 (EPHX1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:bta01002]
    535293 (EPHX1)
Enzymes [BR:bta01000]
 3. Hydrolases
  3.3  Acting on ether bonds
   3.3.2  Ether hydrolases
    3.3.2.9  microsomal epoxide hydrolase
     535293 (EPHX1)
Peptidases and inhibitors [BR:bta01002]
 Serine peptidases
  Family S33
   535293 (EPHX1)
SSDB
Motif
Pfam: EHN Abhydrolase_1 Abhydrolase_6
Other DBs
NCBI-GeneID: 535293
NCBI-ProteinID: NP_001029801
BGD-bta: BT14062
Ensembl: ENSBTAG00000000140
VGNC: 28541
UniProt: Q3ZCJ6
Position
16:28833420..28870961
AA seq 451 aa
MWLEILLASVLGFVIYWFVSKDKEETLPLEDGWWGPGVRPTAGEDKSIRPFKVETSDEEI
NDLHQRIDRVRLTPPLEDSRFHYGFNSNYLKKIISYWRNEFDWRKQVEILNKYPHFKTKI
EGLDIHFIHVKPPNLPSGQTPKPLLMVHGWPGSFYEFYKIIPFLTDPKNHGLSDEHVFEV
ICPSIPGYSFSEASSKKGFNSVATARIFYKLMLRLGFQKFYIQGGDWGALICTNMAQLVP
SHIKGLHLNMALILRNFYTLTLPLGRCFGGLFGYTERDMELIYPFKKIFFSLLRESGYLH
IQSTKPDTVGCALNDSPVGLAAYILEKFSTWTNSEFRDLEDGGLERKFSLDDLLTGIMLY
WTTGTITSSQRFYKENLGQVNKHEMLKVYVPTGFAAFPCELMHLPEKWVKTKYPNLISYS
YMPRGGHFAAFEEPELLAQDIRKFVGLQERQ
NT seq 1356 nt   +upstreamnt  +downstreamnt
atgtggctggaaatactccttgcctcagtgctgggctttgtcatctactggttcgtctcc
aaggacaaggaggagactttgccccttgaagatggatggtgggggcctggggtgaggccc
acagctggggaggataagagcatccgcccattcaaggtggaaacatcagatgaggagatc
aatgacttacatcagaggattgacagggtccgtttaactccacctttggaggacagtcgt
ttccactatggtttcaactccaactatttgaagaaaatcatctcctactggaggaatgaa
tttgactggaggaagcaggtggagattctcaacaaataccctcacttcaagactaagatt
gaagggctggacatccacttcatccacgtgaagccccctaacctcccctccggccaaacc
ccaaagcccttgctgatggtgcacggctggcctggctccttctacgagttttataagatc
atcccgttcctgactgaccctaagaaccacggcctgagtgatgagcatgtttttgaagtc
atctgtccatccattcctggctacagcttctccgaggcatcctccaagaagggcttcaac
tcagtggccactgccaggatcttttataagctgatgctgcggctgggcttccagaaattc
tatattcaaggcggggactggggggccctgatctgcaccaacatggcccagctggtgccc
agccacatcaagggcctgcacttgaacatggctttgattttaagaaatttctacaccctg
acccttcctctgggacggtgtttcggggggcttttcggttataccgagagagacatggag
ctgatatacccctttaagaagatcttcttcagcttactgagggagagcggctacttgcac
atccagagcaccaagccggacaccgtgggctgtgctctgaatgactctcccgtgggactg
gctgcctatattctagagaagttttctacctggaccaattcggaattccgagacttggag
gatggaggcctagagaggaagttctccctggacgacctgctgacgggcatcatgctctac
tggacaacaggcaccatcacctcctcccagcgcttctacaaggagaacctggggcaagtc
aataagcatgagatgttgaaggtgtatgtgcccacgggctttgctgccttcccctgtgag
ctgatgcacttgccagaaaagtgggtgaagaccaagtacccgaatctcatctcttattcc
tacatgccccgtgggggccactttgctgcctttgaggagccagagctgcttgcccaggac
atccgcaagttcgtggggctgcaggagcggcagtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (5)   
Chemical substance (18)   
   KEGG COMPOUND (18)   
Chemical reaction (10)   
   KEGG ENZYME (1)   
   KEGG REACTION (9)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   BGD-BTA (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (6)   
   UniProt (1)   
   RefSeq(pep) (5)   
DNA sequence (7)   
   RefSeq(nuc) (5)   
   GenBank (1)   
   EMBL (1)   
Protein domain (3)   
   Pfam (3)   
All databases (64)   

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