KEGG   Bos taurus (cow): 784636
Entry
784636            CDS       T01008                                 
Symbol
AP2A1
Name
(RefSeq) AP-2 complex subunit alpha-1
  KO
K11824  AP-2 complex subunit alpha
Organism
bta  Bos taurus (cow)
Pathway
bta04144  Endocytosis
bta04721  Synaptic vesicle cycle
bta04961  Endocrine and other factor-regulated calcium reabsorption
bta05016  Huntington disease
Brite
KEGG Orthology (KO) [BR:bta00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    784636 (AP2A1)
 09150 Organismal Systems
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    784636 (AP2A1)
  09156 Nervous system
   04721 Synaptic vesicle cycle
    784636 (AP2A1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    784636 (AP2A1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:bta04131]
    784636 (AP2A1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:bta04147]
    784636 (AP2A1)
Membrane trafficking [BR:bta04131]
 Endocytosis
  Clathrin-mediated endocytosis
   AP-2 complex
    784636 (AP2A1)
Exosome [BR:bta04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   784636 (AP2A1)
SSDB
Motif
Pfam: Adaptin_N Alpha_adaptin_C Alpha_adaptinC2 Cnd1 HEAT_2 RIX1 AcMNPV_Ac75 PDS5
Other DBs
NCBI-GeneID: 784636
NCBI-ProteinID: NP_001178369
Ensembl: ENSBTAG00000019180
VGNC: 25983
UniProt: A0A3Q1LVF9 Q1JPJ7
Position
18:56137675..56165604
AA seq 978 aa
MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVC
KLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDL
ASRNPTFMCLALHCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYKASP
DLVPMGEWTARVVHLLNDQHMGVVTAAVSLITCLCKKNPDDFKTCVSLAVSRLSRIVSSA
STDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKV
QHSNAKNAILFETISLIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSE
FSHEAVKTHIDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAI
REEIVLKVAILAEKYAVDYSWYVDTILNLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAA
KTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPPVQFSLLHSKFHLCSVATRAL
LLSTYIKFINLFPETKATIQGVLRAGSQLRNADVELQQRAVEYLTLSSVASTDVLATVLE
EMPPFPERESSILAKLKRKKGPGAGSALDDSRRDPSSHDINGGVEPTPSTVSTPSPSADL
LGLRAAPPPAAPPAPSGAGNLLVDVFSDSPAAQPGLGPSPEEAFLSELEPPAPESPMALL
ADPAPAADPGPEDIGPPIPEADELLNKFVCRNNGVLFENQLLQIGVKSEFRQNLGRMYLF
YGNKTSVQFQNFSPTVVHPGDLQTQLAVQTKRVASQVDGGAQVQQVLNIECLRDFLTPPL
LSVRFRYGGAPQSLTLKLPVTINKFFQPTEMAAQDFFQRWKQLSLPQQEAQKIFKANHPM
DAEVTKAKLLGFGSALLDNVDPNPENFVGAGIIQTKALQVGCLLRLEPNAQAQMYRLTLR
TSKEPVSRHLCELLAQQF
NT seq 2937 nt   +upstreamnt  +downstreamnt
atgccggccgtgtccaagggcgatgggatgcgggggctcgccgtgttcatctccgacatc
cggaactgtaagagcaaggaggcagagattaagagaatcaacaaggaactggccaacatc
cgctccaagttcaagggggacaaagccttggacggctacagcaagaaaaagtatgtgtgt
aaactgctcttcatcttcctgcttggccacgacattgactttgggcacatggaggctgtg
aacctgctgagctccaacaagtacacagagaagcagattggttacctgttcatctcggtg
ctggtgaactccaactccgagttgatccggctcatcaacaacgccatcaagaatgacctg
gccagccgcaaccccaccttcatgtgcctggccctgcactgcatcgccaacgtgggcagc
cgcgagatgggagaggccttcgccgctgacatccctcgcatcttggtggccggggacagc
atggacagcgtgaagcagagcgcggccctgtgcctgctgcggctctacaaggcctcgccc
gacctggtgcccatgggcgagtggacggcccgcgtggtgcacttgctcaacgaccagcac
atgggcgtggtcacagccgctgtcagcctcatcacctgtctctgcaagaagaacccggat
gacttcaagacgtgcgtctccctggctgtgtctcgcctaagccggatcgtctcctcggcc
tccactgacctccaggactacacctactacttcgtgccagcgccctggctctccgtgaag
ctcctgcggctgctgcagtgctacccgccaccagaggacgcggccgtgaaggggcggctg
gtggagtgcctggagaccgtgctcaacaaggcccaggagccgcccaagtccaaaaaggtc
cagcactccaacgccaagaacgccatcctcttcgagaccatcagcctcattatccactac
gacagtgagcccaacctcctggttcgggcctgtaaccagctgggccagttcctgcagcac
cgggagaccaacctgcgctacctggccctggagagcatgtgcacgctggccagctccgag
ttctcccacgaggcggtcaagacgcacatcgacaccgtcatcaacgccctcaagacggag
cgggacgtcagtgtgcggcagcgggcggctgacctcctctacgccatgtgtgatcggagc
aacgccaagcagatcgtgtcagagatgctgcggtacctggaaacggccgactacgccatt
cgtgaagagattgtcctgaaggtggccatcctggctgagaagtacgccgtggactacagc
tggtacgtggacaccatcctgaacctcatccgcatcgcgggcgactacgtgagcgaggag
gtgtggtaccgcgtgctgcagatcgtcaccaaccgcgacgacgtgcagggctacgctgcc
aagaccgtcttcgaggcgctccaggcgcccgcctgccatgagaacatggtgaaggtcggc
ggctacatccttggggagtttggaaacctgattgctggggacccccgctccagccccccg
gtgcagttctccctgctgcattccaagttccacctgtgcagcgtggccacgcgggcccta
ctgctctccacctacatcaagttcatcaacctcttcccggaaaccaaggccaccatccag
ggcgtgctgcgagccggctcccagctgcgcaacgccgacgtggagctccagcagcgggct
gtcgagtacctcaccctgagctcggtggccagcacggacgtcctggccacggtgctggag
gagatgccacccttccccgagcgtgagtcatccatcctggccaagctgaagcgcaagaag
gggccgggggccggcagcgccctggatgacagccggagggaccccagcagccacgacatc
aatgggggcgtggagcccacccccagcaccgtttccacaccctcgccctccgctgacctc
ctggggctgcgggcagcccctccccccgcggcacccccggccccctcgggtgcaggcaac
ctcctggtggacgtcttctccgacagcccggccgcccagcccggcctggggcccagcccc
gaggaggccttcctcagcgagctggagccgcctgcccctgagagccccatggctttgctg
gctgacccagctccagctgctgacccaggtcctgaggacattggcccgcccatcccagaa
gctgatgagctgctgaataagttcgtgtgcaggaacaatggggtcctgtttgagaaccag
ctgctgcagattggagtcaagtcagagttccggcagaacttgggccgcatgtatctcttc
tatggcaacaagacctcggtgcagttccagaacttctctcccactgtggttcaccctgga
gacctccagactcagctggccgtgcagaccaagcgggtggcctcgcaggtggacggcggg
gcgcaggtgcagcaggtgctcaacattgagtgtctgcgggacttcctgacgccgccgctc
ctgtcggtgcgcttccggtacgggggcgccccccagtccctcaccctgaaactcccagtg
accatcaacaagttcttccagccgacggagatggcggcccaggacttcttccagcgttgg
aagcagctgagcctcccccaacaggaggcccagaaaatcttcaaagccaaccaccccatg
gacgcggaggtcactaaggccaagctcctggggtttggctctgctctcctggacaatgtg
gaccccaaccctgagaacttcgtgggggctggaatcatccagactaaagccctgcaggtg
ggctgtctgctccggctggagcccaatgcccaggctcagatgtaccggctgaccctgcgc
accagcaaggaacccgtctcccgtcacctgtgtgagctgctggcgcagcagttctga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (6)   
   UniProt (2)   
   RefSeq(pep) (4)   
DNA sequence (16)   
   RefSeq(nuc) (4)   
   GenBank (6)   
   EMBL (6)   
Protein domain (8)   
   Pfam (8)   
All databases (50)   

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