KEGG   Castor canadensis (American beaver): 109685333
Entry
109685333         CDS       T04791                                 
Symbol
Gsk3b
Name
(RefSeq) glycogen synthase kinase-3 beta
  KO
K03083  glycogen synthase kinase 3 beta [EC:2.7.11.26]
Organism
ccan  Castor canadensis (American beaver)
Pathway
ccan01521  EGFR tyrosine kinase inhibitor resistance
ccan04012  ErbB signaling pathway
ccan04062  Chemokine signaling pathway
ccan04110  Cell cycle
ccan04150  mTOR signaling pathway
ccan04151  PI3K-Akt signaling pathway
ccan04310  Wnt signaling pathway
ccan04340  Hedgehog signaling pathway
ccan04360  Axon guidance
ccan04390  Hippo signaling pathway
ccan04510  Focal adhesion
ccan04550  Signaling pathways regulating pluripotency of stem cells
ccan04657  IL-17 signaling pathway
ccan04660  T cell receptor signaling pathway
ccan04662  B cell receptor signaling pathway
ccan04722  Neurotrophin signaling pathway
ccan04728  Dopaminergic synapse
ccan04910  Insulin signaling pathway
ccan04916  Melanogenesis
ccan04917  Prolactin signaling pathway
ccan04919  Thyroid hormone signaling pathway
ccan04931  Insulin resistance
ccan04932  Non-alcoholic fatty liver disease
ccan04934  Cushing syndrome
ccan04935  Growth hormone synthesis, secretion and action
ccan04936  Alcoholic liver disease
ccan05010  Alzheimer disease
ccan05020  Prion disease
ccan05022  Pathways of neurodegeneration - multiple diseases
ccan05135  Yersinia infection
ccan05160  Hepatitis C
ccan05162  Measles
ccan05163  Human cytomegalovirus infection
ccan05165  Human papillomavirus infection
ccan05167  Kaposi sarcoma-associated herpesvirus infection
ccan05200  Pathways in cancer
ccan05210  Colorectal cancer
ccan05213  Endometrial cancer
ccan05215  Prostate cancer
ccan05217  Basal cell carcinoma
ccan05224  Breast cancer
ccan05225  Hepatocellular carcinoma
ccan05226  Gastric cancer
ccan05415  Diabetic cardiomyopathy
ccan05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ccan00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    109685333 (Gsk3b)
   04310 Wnt signaling pathway
    109685333 (Gsk3b)
   04340 Hedgehog signaling pathway
    109685333 (Gsk3b)
   04390 Hippo signaling pathway
    109685333 (Gsk3b)
   04151 PI3K-Akt signaling pathway
    109685333 (Gsk3b)
   04150 mTOR signaling pathway
    109685333 (Gsk3b)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    109685333 (Gsk3b)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    109685333 (Gsk3b)
   04550 Signaling pathways regulating pluripotency of stem cells
    109685333 (Gsk3b)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    109685333 (Gsk3b)
   04657 IL-17 signaling pathway
    109685333 (Gsk3b)
   04662 B cell receptor signaling pathway
    109685333 (Gsk3b)
   04062 Chemokine signaling pathway
    109685333 (Gsk3b)
  09152 Endocrine system
   04910 Insulin signaling pathway
    109685333 (Gsk3b)
   04917 Prolactin signaling pathway
    109685333 (Gsk3b)
   04935 Growth hormone synthesis, secretion and action
    109685333 (Gsk3b)
   04919 Thyroid hormone signaling pathway
    109685333 (Gsk3b)
   04916 Melanogenesis
    109685333 (Gsk3b)
  09156 Nervous system
   04728 Dopaminergic synapse
    109685333 (Gsk3b)
   04722 Neurotrophin signaling pathway
    109685333 (Gsk3b)
  09158 Development and regeneration
   04360 Axon guidance
    109685333 (Gsk3b)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    109685333 (Gsk3b)
  09162 Cancer: specific types
   05210 Colorectal cancer
    109685333 (Gsk3b)
   05225 Hepatocellular carcinoma
    109685333 (Gsk3b)
   05226 Gastric cancer
    109685333 (Gsk3b)
   05217 Basal cell carcinoma
    109685333 (Gsk3b)
   05215 Prostate cancer
    109685333 (Gsk3b)
   05213 Endometrial cancer
    109685333 (Gsk3b)
   05224 Breast cancer
    109685333 (Gsk3b)
  09172 Infectious disease: viral
   05160 Hepatitis C
    109685333 (Gsk3b)
   05162 Measles
    109685333 (Gsk3b)
   05163 Human cytomegalovirus infection
    109685333 (Gsk3b)
   05167 Kaposi sarcoma-associated herpesvirus infection
    109685333 (Gsk3b)
   05165 Human papillomavirus infection
    109685333 (Gsk3b)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    109685333 (Gsk3b)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    109685333 (Gsk3b)
   05020 Prion disease
    109685333 (Gsk3b)
   05022 Pathways of neurodegeneration - multiple diseases
    109685333 (Gsk3b)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    109685333 (Gsk3b)
   05415 Diabetic cardiomyopathy
    109685333 (Gsk3b)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    109685333 (Gsk3b)
   04932 Non-alcoholic fatty liver disease
    109685333 (Gsk3b)
   04931 Insulin resistance
    109685333 (Gsk3b)
   04934 Cushing syndrome
    109685333 (Gsk3b)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    109685333 (Gsk3b)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ccan01001]
    109685333 (Gsk3b)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:ccan03036]
    109685333 (Gsk3b)
Enzymes [BR:ccan01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.26  tau-protein kinase
     109685333 (Gsk3b)
Protein kinases [BR:ccan01001]
 Serine/threonine kinases: CMGC group
  GSK family [OT]
   109685333 (Gsk3b)
Chromosome and associated proteins [BR:ccan03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    109685333 (Gsk3b)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kinase-like Kdo APH Choline_kinase
Other DBs
NCBI-GeneID: 109685333
NCBI-ProteinID: XP_020017718
UniProt: A0A8B7UDL0
Position
Unknown
AA seq 442 aa
MTTVLLTGIELRALQGYVTHVPCCFSLLFKQGLVLLPVMASDSDLSTSTSKRDKDGSKVT
TVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNREL
QIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYV
KLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYIC
SRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTR
EQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHS
FFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAAASTPTNATAAS
DANAGDRGQTNNAASASASNST
NT seq 1329 nt   +upstreamnt  +downstreamnt
atgaccacagtactccttacagggattgaactcagggccttgcaaggctacgtgacccat
gtcccctgttgttttagtttgcttttcaaacaaggcctcgtacttttgcctgtgatggct
tcagacagtgatctttctacctcaacctccaaaagagataaggatggcagcaaggtgacc
acagtggtggcaactcctgggcagggtccagataggccacaagaagtcagctatacagat
actaaagtgattggaaatggatcatttggtgtggtgtatcaagccaaactttgtgattca
ggagaattggttgccatcaagaaagtattacaggacaagagatttaagaaccgagagctc
cagatcatgagaaagctagatcactgtaacatagtccgattgcgttatttcttctactca
agcggtgagaagaaagatgaggtctaccttaatctggtgctggactatgttccggaaaca
gtgtacagagttgccagacactatagtcgagccaaacaaacactccctgtgatctatgtc
aagttgtatatgtatcagctgttcagaagtttagcctatatccattcctttggaatttgc
catcgggatattaaaccacaaaacctcctgctggatcctgacacggctgtcttaaaactc
tgtgattttggaagtgcaaagcagctggtccgaggagaacccaatgtttcgtatatctgt
tctcggtactatagggcaccagagttgatctttggagccactgattatacctctagtata
gatgtatggtctgcgggctgtgtgttagctgagctgttgctaggacaaccaatatttcca
ggggacagtggtgtggatcaattggtggaaataatcaaggtcctgggaacaccaacaagg
gagcaaattagagaaatgaacccaaattatacagaattcaaattccctcaaattaaggca
catccttggacaaaggtcttccgaccccgaactccaccagaagcaattgcactgtgtagc
cgtctactggagtatacaccaactgcccgattgacaccactagaggcttgtgcacattca
ttttttgatgaattacgggacccaaatgtcaaactaccaaatgggcgagacacacctgca
ctcttcaacttcactactcaagaactttcaagtaatccacctctggctaccatccttatt
cctcctcatgctcggattcaagcagctgcttcaactcctacaaatgccacagcagcctca
gatgctaatgctggagaccgtgggcagaccaataacgccgcttctgcatcagcttccaac
tccacctga

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