KEGG   Castor canadensis (American beaver): 109689613
Entry
109689613         CDS       T04791                                 
Symbol
Casp8
Name
(RefSeq) caspase-8
  KO
K04398  caspase 8 [EC:3.4.22.61]
Organism
ccan  Castor canadensis (American beaver)
Pathway
ccan01524  Platinum drug resistance
ccan04115  p53 signaling pathway
ccan04210  Apoptosis
ccan04215  Apoptosis - multiple species
ccan04217  Necroptosis
ccan04620  Toll-like receptor signaling pathway
ccan04621  NOD-like receptor signaling pathway
ccan04622  RIG-I-like receptor signaling pathway
ccan04623  Cytosolic DNA-sensing pathway
ccan04625  C-type lectin receptor signaling pathway
ccan04657  IL-17 signaling pathway
ccan04668  TNF signaling pathway
ccan04932  Non-alcoholic fatty liver disease
ccan04936  Alcoholic liver disease
ccan05010  Alzheimer disease
ccan05016  Huntington disease
ccan05022  Pathways of neurodegeneration - multiple diseases
ccan05132  Salmonella infection
ccan05134  Legionellosis
ccan05142  Chagas disease
ccan05145  Toxoplasmosis
ccan05152  Tuberculosis
ccan05160  Hepatitis C
ccan05161  Hepatitis B
ccan05162  Measles
ccan05163  Human cytomegalovirus infection
ccan05164  Influenza A
ccan05165  Human papillomavirus infection
ccan05167  Kaposi sarcoma-associated herpesvirus infection
ccan05168  Herpes simplex virus 1 infection
ccan05169  Epstein-Barr virus infection
ccan05170  Human immunodeficiency virus 1 infection
ccan05200  Pathways in cancer
ccan05203  Viral carcinogenesis
ccan05416  Viral myocarditis
ccan05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ccan00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04668 TNF signaling pathway
    109689613 (Casp8)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    109689613 (Casp8)
   04215 Apoptosis - multiple species
    109689613 (Casp8)
   04217 Necroptosis
    109689613 (Casp8)
   04115 p53 signaling pathway
    109689613 (Casp8)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    109689613 (Casp8)
   04621 NOD-like receptor signaling pathway
    109689613 (Casp8)
   04622 RIG-I-like receptor signaling pathway
    109689613 (Casp8)
   04623 Cytosolic DNA-sensing pathway
    109689613 (Casp8)
   04625 C-type lectin receptor signaling pathway
    109689613 (Casp8)
   04657 IL-17 signaling pathway
    109689613 (Casp8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    109689613 (Casp8)
   05203 Viral carcinogenesis
    109689613 (Casp8)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    109689613 (Casp8)
   05161 Hepatitis B
    109689613 (Casp8)
   05160 Hepatitis C
    109689613 (Casp8)
   05164 Influenza A
    109689613 (Casp8)
   05162 Measles
    109689613 (Casp8)
   05168 Herpes simplex virus 1 infection
    109689613 (Casp8)
   05163 Human cytomegalovirus infection
    109689613 (Casp8)
   05167 Kaposi sarcoma-associated herpesvirus infection
    109689613 (Casp8)
   05169 Epstein-Barr virus infection
    109689613 (Casp8)
   05165 Human papillomavirus infection
    109689613 (Casp8)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    109689613 (Casp8)
   05134 Legionellosis
    109689613 (Casp8)
   05152 Tuberculosis
    109689613 (Casp8)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    109689613 (Casp8)
   05142 Chagas disease
    109689613 (Casp8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    109689613 (Casp8)
   05016 Huntington disease
    109689613 (Casp8)
   05022 Pathways of neurodegeneration - multiple diseases
    109689613 (Casp8)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    109689613 (Casp8)
   05416 Viral myocarditis
    109689613 (Casp8)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    109689613 (Casp8)
   04932 Non-alcoholic fatty liver disease
    109689613 (Casp8)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    109689613 (Casp8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:ccan01002]
    109689613 (Casp8)
Enzymes [BR:ccan01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.61  caspase-8
     109689613 (Casp8)
Peptidases and inhibitors [BR:ccan01002]
 Cysteine peptidases
  Family C14: caspase family
   109689613 (Casp8)
SSDB
Motif
Pfam: Peptidase_C14 DED PYRIN
Other DBs
NCBI-GeneID: 109689613
NCBI-ProteinID: XP_020024141
UniProt: A0A8B7UWT7
Position
Unknown
AA seq 483 aa
MDFSECLYNIGEQLDSDELASLKFLSLDYIPQKKQEPIKDTLMLFQRLQEKGMLEEGNLS
FLKELLFRINRLDLLQTFLATTKEEMEKELQILGRAQISAYRVMLFQVSEDVDKQELKSF
KFFLNKEISKCKLDNDMSLLDIFTEMEKRVLLGETNLDILKRICEQINKSLLGKINDYEL
RRCSDNLTERRMSIEGCSDSFLNGEGSLGALAMSDSPREQDSESQTSDKAYQMKNKPRGY
CLIFNNYDFSVARKSVPKLHNIKDRKGTDLDEETLRQTFKMLHFEIILYKNATAKEIYEV
LQSYQTMDHNNKDCFVCCILSHGDKGIVYGTDGKQASIYELTSYFTGSKCPSLAGKPKVF
FIQACQGENYHQAIPIDTDSEQDTYLEMDSSSQKRYIPDEADFLLGMATVTNCVSYRDPL
RGTWFIQSLCRSLKERCPLGDDILTILTEVNYEVSNKDDWKNMGKQMPQPTFTLRKKLFF
PLK
NT seq 1452 nt   +upstreamnt  +downstreamnt
atggatttcagtgagtgtctttacaatattggggagcaacttgacagtgatgagttggcc
tctctcaagttcctgagcctagactacatcccacaaaagaaacaagagcccatcaaggat
actttgatgctattccagagactgcaggagaaaggaatgttggaggaaggcaatctgtcc
ttcttgaaggagctgcttttccgaattaatagactggacctgctgcaaacttttctggcc
acaaccaaggaagagatggaaaaagagctccagattctaggcagggcccagatttctgcc
tacagggtaatgctttttcaagtttcagaagatgtagacaagcaggaattgaagtctttt
aagttttttttgaacaaggagatctccaagtgtaagctggataatgacatgagtttgctc
gatattttcacagagatggagaagagagtcctcctaggtgaaacaaacttggacatcctg
aaaagaatctgtgagcaaatcaacaagagcctgctgggaaagatcaatgactatgaattg
agaagatgtagcgacaatctgacagagagaagaatgagcattgaaggatgttcagattca
tttttgaatggggaggggtccctcggagcactggcaatgtcagactctccaagagaacaa
gacagtgagtcacagacatcggacaaagcttaccaaatgaaaaacaaaccaagaggatac
tgtttaatcttcaacaattacgattttagcgtggcacggaaaagcgtacctaaacttcac
aacattaaggataggaaaggaacagacttggatgaagagactttgagacaaacctttaag
atgcttcattttgagataatactttacaaaaacgccacagcaaaggaaatctatgaggtt
ctacaatcctatcaaactatggaccacaataacaaagactgctttgtctgctgtatcctc
tcccatggagacaaaggcattgtctatggcaccgacggaaagcaggcctccatctatgaa
ctgacatcttatttcactggttccaagtgcccttccctggctggaaaacccaaagtcttt
tttattcaggcttgtcaaggggaaaactatcatcaagctatacctattgacactgactca
gagcaggacacctatttagaaatggactcatcatctcaaaagagatatatcccagatgag
gctgactttctgctggggatggccactgtgaccaactgtgtttcctaccgagaccccttg
agagggacctggtttatccagtcactttgccggagtctgaaggaaagatgtcctctaggt
gatgacattctcaccatcctaactgaagtaaactatgaagtgagcaataaagacgactgg
aagaacatggggaaacagatgccacagcctaccttcacactaaggaaaaaactcttcttc
cctcttaagtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (36)   
   KEGG PATHWAY (36)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (4)   
   RefSeq(nuc) (2)   
   GenBank (1)   
   EMBL (1)   
Protein domain (3)   
   Pfam (3)   
All databases (70)   

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