KEGG   Camelus dromedarius (Arabian camel): 105091254
Entry
105091254         CDS       T04642                                 
Symbol
ROCK2
Name
(RefSeq) rho-associated protein kinase 2 isoform X1
  KO
K17388  Rho-associated protein kinase 2 [EC:2.7.11.1]
Organism
cdk  Camelus dromedarius (Arabian camel)
Pathway
cdk04022  cGMP-PKG signaling pathway
cdk04024  cAMP signaling pathway
cdk04062  Chemokine signaling pathway
cdk04071  Sphingolipid signaling pathway
cdk04270  Vascular smooth muscle contraction
cdk04310  Wnt signaling pathway
cdk04360  Axon guidance
cdk04510  Focal adhesion
cdk04520  Adherens junction
cdk04530  Tight junction
cdk04611  Platelet activation
cdk04670  Leukocyte transendothelial migration
cdk04810  Regulation of actin cytoskeleton
cdk04921  Oxytocin signaling pathway
cdk05132  Salmonella infection
cdk05135  Yersinia infection
cdk05163  Human cytomegalovirus infection
cdk05200  Pathways in cancer
cdk05205  Proteoglycans in cancer
cdk05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cdk00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    105091254 (ROCK2)
   04071 Sphingolipid signaling pathway
    105091254 (ROCK2)
   04024 cAMP signaling pathway
    105091254 (ROCK2)
   04022 cGMP-PKG signaling pathway
    105091254 (ROCK2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    105091254 (ROCK2)
   04520 Adherens junction
    105091254 (ROCK2)
   04530 Tight junction
    105091254 (ROCK2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    105091254 (ROCK2)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    105091254 (ROCK2)
   04670 Leukocyte transendothelial migration
    105091254 (ROCK2)
   04062 Chemokine signaling pathway
    105091254 (ROCK2)
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    105091254 (ROCK2)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    105091254 (ROCK2)
  09158 Development and regeneration
   04360 Axon guidance
    105091254 (ROCK2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105091254 (ROCK2)
   05205 Proteoglycans in cancer
    105091254 (ROCK2)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    105091254 (ROCK2)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    105091254 (ROCK2)
   05135 Yersinia infection
    105091254 (ROCK2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105091254 (ROCK2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cdk01001]
    105091254 (ROCK2)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:cdk03036]
    105091254 (ROCK2)
Enzymes [BR:cdk01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     105091254 (ROCK2)
Protein kinases [BR:cdk01001]
 Serine/threonine kinases: AGC group
  DMPK family [OT]
   105091254 (ROCK2)
Chromosome and associated proteins [BR:cdk03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    105091254 (ROCK2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Rho_Binding PH C1_1 APH Pkinase_C Irp3-like_C
Other DBs
NCBI-GeneID: 105091254
NCBI-ProteinID: XP_031322436
Position
15:complement(7050445..7174317)
AA seq 1500 aa
MSRPPPTGKMPGAPAAVSGDGSGTSRQRKLEALIRDPRSPINVESLLDGLNSLVLDLDFP
ALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAM
KLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFCAFQDDKYLYMVMEYMPGGDLVNL
MSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMD
ETGMVHCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLV
GTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIKQHPFFKNDQWN
WDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTYYRENL
LLSDSPPSCRENDSIQSRKNEESQEIQKKLYTLEEHLSTEIQAKEELEQKCKSVNTRLEK
VAKELEEEINLRKNVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQ
LEDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAECSKQIQQLESNN
RDLQDKNCLLETAKLKLEKEFINLQSVLESERRDRTHGSEIINDLQGRISGLEEDLKNGK
ILLAKVEVEKRQLQERFTDLEKIKQSQQGSHNRVEVWEMGTVGSEQEKNNMEIDMTYQLK
VIQQSLEQEEAEHKATKARLADKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLL
EAEKRCSILDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQ
QVNTLKMSEKQLKQENNHLMEMKMSLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTL
YKTQVRELKEECEEKTKLCKELQQKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQ
YSDLEKEKIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNK
LKDAQEQLSRLKDEEISAAAIKAQFEKQLLTERTLKTQAVNKLAEIMNRKEPVKRGSDTD
VRRKEKENRKLHMELKSEREKLTQQMIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSD
IEQLRSQLQALHIGLDSSSIGSGPGDAEADDGFPVHITQSHTMESMSFTYQRSSTSLNIA
TKPSSSHMLLDSDSDSEEESVHYLPISAEPNGTESRLEGWLSLPVRNNTKKFGWVKKYVI
VSSKKILFYDSEQDKEQSNPYMVLDIDKLFHVRPVTQTDVYRADAKEIPRIFQILYANEG
ESKKEQEFPVEPVGEKSNYICHKGHEFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRC
HIKCHKDHMDKKEEIIAPCKVYYDISSAKNLLLLANSTEEQQKWVSRLVKKIPKKPPAPD
PFARSSPRTSMKIQQNQSIRRPSRQLAPNKPRLLDLAFKDWDWSFDDIDGGDDDGDVFDF
NT seq 4503 nt   +upstreamnt  +downstreamnt
atgagccggcccccgccgacggggaaaatgcccggcgcccccgcggccgtgtcgggggac
ggctcgggcacgagccgccagaggaagctggaggcgctgatccgagaccctcgctcaccc
atcaacgtggagagcttgctggatggattaaattccttggtccttgatttggattttcct
gctttgaggaaaaacaagaatatagataatttcttaaatagatatgagaaaattgtgaaa
aagatcagaggtctacagatgaaggcagaagactatgatgttgtaaaagttattggaaga
ggtgcttttggtgaagtccagttggttcgtcataaggcatcacagaaagtttatgctatg
aagcttcttagtaaatttgaaatgataaaaagatcagattctgcttttttctgggaagaa
agagatattatggcctttgccaacagtccctgggtggttcagctcttttgtgcctttcag
gatgataaatatctgtacatggtaatggagtacatgcctggtggagaccttgtaaacctt
atgagtaactatgatgtacctgaaaagtgggccaaattttatactgctgaagtggttctt
gctttggatgccatacactccatgggtttaattcacagagatgtgaagcctgacaatatg
ctcttggataaacacggacatctaaaattagcagattttggcacatgtatgaagatggat
gaaacaggcatggtgcattgtgatacagcagttggaacacctgattatatatcacctgaa
gttctgaaatcacaagggggtgatggttactatgggagagaatgtgattggtggtctgtg
ggtgttttcctttttgagatgctggtgggagacactccattttacgcagattcacttgta
gggacatacagcaaaatcatggatcataaaaactcactatgtttccctgaagatgcagaa
atttctaaacatgcgaagaatctcatctgtgccttcttaacagatagggaggtacgactt
gggagaaatggggtagaagaaatcaaacaacatcctttctttaagaatgatcagtggaat
tgggataacataagagagacggcagctcctgtggtacctgaactcagcagtgacatagac
agcagcaattttgatgatattgaagatgacaaaggagatgtggaaacctttccaattcct
aaagcttttgtggggaatcagctgccttttataggatttacctattatagagaaaatttg
ttattaagtgactctcctccctcttgtagagaaaatgattcaatacagtcaaggaagaat
gaagaaagtcaagagattcagaaaaaactgtacacattagaagaacaccttagcactgag
atacaagccaaagaggaactagagcagaagtgcaaatctgttaatactcgtctagagaaa
gtagcaaaggagctagaagaagagattaacttacggaaaaatgtggaatcagcattaaga
caattagaaagagaaaaggcgcttcttcagcacaaaaatgcagaataccagcggaaagct
gatcatgaagcagacaagaaacgaaatttggaaaatgatgttaacagtttaaaagatcaa
cttgaagatttgaaaaaaagaaatcagaactctcagatatctactgagaaagtgaatcaa
ctccagagacaactggatgaaaccaatgctttgctgcgaacagaatcggatactgcagcc
cggttaagaaaaacccaggcagaatgttcaaaacagattcagcagctggaatctaacaat
agagatctacaagataaaaactgcctgctggagactgccaagttaaaacttgaaaaggaa
tttattaatctccagtcagttctcgaatctgaaaggagggaccgaacccatggatcagag
attattaatgatttacaaggtagaatatctggcctagaagaagatttaaagaatggcaaa
atcttattagcaaaagtagaggtggagaagagacaactacaggagagatttactgatttg
gaaaagatcaagcaatctcaacaaggatctcacaacagagtggaggtgtgggagatgggt
acagtggggagcgaacaggagaagaacaacatggaaatagatatgacataccaactcaaa
gttatacagcagagcttagaacaggaagaagcggaacataaggctacaaaagcacggctg
gcagataaaaataagatttatgaatccattgaagaggctaagtcagaagccatgaaagaa
atggagaaaaagctcttggaggaaagaactttaaaacagaaagtggagaacttgttgctg
gaggctgagaaaagatgttctatattagactgtgacctcaaacagtcacagcagaaaata
aatgaactcctcaaacaaaaagatgtgctaaatgaggatgttagaaacttgacattaaaa
atagagcaggaaactcagaagcgctgccttacacaaaatgacttgaagatgcaaacacag
caagttaacacactaaaaatgtcagaaaagcagttaaaacaagaaaataatcatctcatg
gaaatgaaaatgagtttggaaaaacagaatgctgaacttcgaaaagaacgccaagatgca
gatgggcaaatgaaagagctccaagaccagcttgaagcagagcagtatttctcaaccctc
tataaaacacaggttagggaacttaaagaagaatgtgaagaaaagaccaaactttgtaaa
gaattacagcagaagaaacaggaattacaggatgaaagggattccttggctgctcagctg
gagatcaccttgaccaaagcagattctgaacaactggctcgctcaattgctgaagagcag
tattctgatttggaaaaagagaagatcatgaaagagctggagatcaaggagatgatggct
agacacaaacaggagctcactgaaaaagatgctacaattgcatctcttgaagaaactaat
aggacactaactagtgatgttgccaatcttgcaaatgagaaagaagagttaaataacaaa
ttgaaagatgcccaagagcaactgtcaaggttgaaggatgaagaaataagtgcagcagct
attaaagcacaatttgagaagcagctgttaacagagagaacactcaaaactcaagctgtg
aataagttggctgagatcatgaatcggaaagaacctgtcaaacgtggtagtgacacagat
gtgcggagaaaagagaaggagaatagaaagctacatatggagcttaaatctgaacgtgag
aagctgacgcagcagatgatcaagtatcagaaagaactgaatgaaatgcaggctcaaata
gctgaagagagccagattcgaattgaactgcagatgaccctggacagtaaagacagtgac
attgagcagctgcggtcccagctccaagccttgcatattggtctggatagttccagtata
ggcagtggaccaggggatgctgaagcagatgatgggttcccagttcatatcactcagtca
cacactatggaatccatgtcattcacctaccaacgttcctctacttctctcaatattgcc
actaagccttccagttctcatatgcttcttgactctgattctgactcagaagaagaatct
gtgcattatttacctatttcagcggaacctaatggtacagaatcaagactagaaggttgg
ctttcattgcctgtgcgaaacaacactaagaaatttggatgggttaaaaagtatgtgatt
gtaagtagtaagaagatccttttctatgacagtgaacaagataaagaacaatctaatcct
tacatggttttagatatagacaaattatttcatgtacgaccagttacacagacagatgta
tatagagcagatgctaaagaaattccaaggatattccagattttgtatgccaatgaagga
gaaagtaagaaggaacaagaatttccagtggagccagtgggagaaaagtcaaattacatt
tgccacaaaggacatgaatttattcccactctctatcatttcccaaccaactgtgaggca
tgtatgaagccattatggcatatgtttaaacctcctcctgctttagagtgccgtcgctgc
catattaaatgtcataaagatcacatggataaaaaggaggaaattatagcaccttgcaaa
gtgtattatgatatttcatcggcaaagaacctattgttattagcaaattctacagaagag
cagcaaaagtgggttagtcggctagtgaaaaaaatacctaaaaagcctccagctccagac
ccttttgcacggtcctctcctagaacttcaatgaagatacaacaaaaccagtctattaga
cggccaagtcgacagcttgccccgaacaaaccaagattgcttgatttggcatttaaagac
tgggattggtcatttgatgatattgatggtggtgatgatgatggcgatgtttttgatttc
tga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (20)   
   KEGG PATHWAY (20)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (4)   
   RefSeq(pep) (4)   
DNA sequence (10)   
   RefSeq(nuc) (4)   
   GenBank (3)   
   EMBL (3)   
Protein domain (8)   
   Pfam (8)   
All databases (52)   

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