KEGG   Camelus dromedarius (Arabian camel): 105099264
Entry
105099264         CDS       T04642                                 
Symbol
AKT3
Name
(RefSeq) RAC-gamma serine/threonine-protein kinase isoform X3
  KO
K04456  RAC serine/threonine-protein kinase [EC:2.7.11.1]
Organism
cdk  Camelus dromedarius (Arabian camel)
Pathway
cdk01521  EGFR tyrosine kinase inhibitor resistance
cdk01522  Endocrine resistance
cdk01524  Platinum drug resistance
cdk04010  MAPK signaling pathway
cdk04012  ErbB signaling pathway
cdk04014  Ras signaling pathway
cdk04015  Rap1 signaling pathway
cdk04022  cGMP-PKG signaling pathway
cdk04024  cAMP signaling pathway
cdk04062  Chemokine signaling pathway
cdk04066  HIF-1 signaling pathway
cdk04068  FoxO signaling pathway
cdk04071  Sphingolipid signaling pathway
cdk04072  Phospholipase D signaling pathway
cdk04140  Autophagy - animal
cdk04150  mTOR signaling pathway
cdk04151  PI3K-Akt signaling pathway
cdk04152  AMPK signaling pathway
cdk04210  Apoptosis
cdk04211  Longevity regulating pathway
cdk04213  Longevity regulating pathway - multiple species
cdk04218  Cellular senescence
cdk04261  Adrenergic signaling in cardiomyocytes
cdk04370  VEGF signaling pathway
cdk04371  Apelin signaling pathway
cdk04380  Osteoclast differentiation
cdk04510  Focal adhesion
cdk04550  Signaling pathways regulating pluripotency of stem cells
cdk04611  Platelet activation
cdk04613  Neutrophil extracellular trap formation
cdk04620  Toll-like receptor signaling pathway
cdk04625  C-type lectin receptor signaling pathway
cdk04630  JAK-STAT signaling pathway
cdk04660  T cell receptor signaling pathway
cdk04662  B cell receptor signaling pathway
cdk04664  Fc epsilon RI signaling pathway
cdk04666  Fc gamma R-mediated phagocytosis
cdk04668  TNF signaling pathway
cdk04722  Neurotrophin signaling pathway
cdk04725  Cholinergic synapse
cdk04728  Dopaminergic synapse
cdk04810  Regulation of actin cytoskeleton
cdk04910  Insulin signaling pathway
cdk04914  Progesterone-mediated oocyte maturation
cdk04915  Estrogen signaling pathway
cdk04917  Prolactin signaling pathway
cdk04919  Thyroid hormone signaling pathway
cdk04920  Adipocytokine signaling pathway
cdk04922  Glucagon signaling pathway
cdk04923  Regulation of lipolysis in adipocytes
cdk04926  Relaxin signaling pathway
cdk04929  GnRH secretion
cdk04931  Insulin resistance
cdk04932  Non-alcoholic fatty liver disease
cdk04933  AGE-RAGE signaling pathway in diabetic complications
cdk04935  Growth hormone synthesis, secretion and action
cdk04936  Alcoholic liver disease
cdk04973  Carbohydrate digestion and absorption
cdk05010  Alzheimer disease
cdk05017  Spinocerebellar ataxia
cdk05132  Salmonella infection
cdk05135  Yersinia infection
cdk05142  Chagas disease
cdk05145  Toxoplasmosis
cdk05152  Tuberculosis
cdk05160  Hepatitis C
cdk05161  Hepatitis B
cdk05162  Measles
cdk05163  Human cytomegalovirus infection
cdk05164  Influenza A
cdk05165  Human papillomavirus infection
cdk05166  Human T-cell leukemia virus 1 infection
cdk05167  Kaposi sarcoma-associated herpesvirus infection
cdk05168  Herpes simplex virus 1 infection
cdk05169  Epstein-Barr virus infection
cdk05170  Human immunodeficiency virus 1 infection
cdk05200  Pathways in cancer
cdk05205  Proteoglycans in cancer
cdk05207  Chemical carcinogenesis - receptor activation
cdk05208  Chemical carcinogenesis - reactive oxygen species
cdk05210  Colorectal cancer
cdk05211  Renal cell carcinoma
cdk05212  Pancreatic cancer
cdk05213  Endometrial cancer
cdk05214  Glioma
cdk05215  Prostate cancer
cdk05218  Melanoma
cdk05220  Chronic myeloid leukemia
cdk05221  Acute myeloid leukemia
cdk05222  Small cell lung cancer
cdk05223  Non-small cell lung cancer
cdk05224  Breast cancer
cdk05225  Hepatocellular carcinoma
cdk05226  Gastric cancer
cdk05230  Central carbon metabolism in cancer
cdk05231  Choline metabolism in cancer
cdk05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
cdk05415  Diabetic cardiomyopathy
cdk05417  Lipid and atherosclerosis
cdk05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cdk00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105099264 (AKT3)
   04012 ErbB signaling pathway
    105099264 (AKT3)
   04014 Ras signaling pathway
    105099264 (AKT3)
   04015 Rap1 signaling pathway
    105099264 (AKT3)
   04370 VEGF signaling pathway
    105099264 (AKT3)
   04371 Apelin signaling pathway
    105099264 (AKT3)
   04630 JAK-STAT signaling pathway
    105099264 (AKT3)
   04668 TNF signaling pathway
    105099264 (AKT3)
   04066 HIF-1 signaling pathway
    105099264 (AKT3)
   04068 FoxO signaling pathway
    105099264 (AKT3)
   04072 Phospholipase D signaling pathway
    105099264 (AKT3)
   04071 Sphingolipid signaling pathway
    105099264 (AKT3)
   04024 cAMP signaling pathway
    105099264 (AKT3)
   04022 cGMP-PKG signaling pathway
    105099264 (AKT3)
   04151 PI3K-Akt signaling pathway
    105099264 (AKT3)
   04152 AMPK signaling pathway
    105099264 (AKT3)
   04150 mTOR signaling pathway
    105099264 (AKT3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    105099264 (AKT3)
  09143 Cell growth and death
   04210 Apoptosis
    105099264 (AKT3)
   04218 Cellular senescence
    105099264 (AKT3)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    105099264 (AKT3)
   04550 Signaling pathways regulating pluripotency of stem cells
    105099264 (AKT3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    105099264 (AKT3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    105099264 (AKT3)
   04613 Neutrophil extracellular trap formation
    105099264 (AKT3)
   04620 Toll-like receptor signaling pathway
    105099264 (AKT3)
   04625 C-type lectin receptor signaling pathway
    105099264 (AKT3)
   04660 T cell receptor signaling pathway
    105099264 (AKT3)
   04662 B cell receptor signaling pathway
    105099264 (AKT3)
   04664 Fc epsilon RI signaling pathway
    105099264 (AKT3)
   04666 Fc gamma R-mediated phagocytosis
    105099264 (AKT3)
   04062 Chemokine signaling pathway
    105099264 (AKT3)
  09152 Endocrine system
   04910 Insulin signaling pathway
    105099264 (AKT3)
   04922 Glucagon signaling pathway
    105099264 (AKT3)
   04923 Regulation of lipolysis in adipocytes
    105099264 (AKT3)
   04920 Adipocytokine signaling pathway
    105099264 (AKT3)
   04929 GnRH secretion
    105099264 (AKT3)
   04915 Estrogen signaling pathway
    105099264 (AKT3)
   04914 Progesterone-mediated oocyte maturation
    105099264 (AKT3)
   04917 Prolactin signaling pathway
    105099264 (AKT3)
   04926 Relaxin signaling pathway
    105099264 (AKT3)
   04935 Growth hormone synthesis, secretion and action
    105099264 (AKT3)
   04919 Thyroid hormone signaling pathway
    105099264 (AKT3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    105099264 (AKT3)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    105099264 (AKT3)
  09156 Nervous system
   04725 Cholinergic synapse
    105099264 (AKT3)
   04728 Dopaminergic synapse
    105099264 (AKT3)
   04722 Neurotrophin signaling pathway
    105099264 (AKT3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    105099264 (AKT3)
  09149 Aging
   04211 Longevity regulating pathway
    105099264 (AKT3)
   04213 Longevity regulating pathway - multiple species
    105099264 (AKT3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105099264 (AKT3)
   05205 Proteoglycans in cancer
    105099264 (AKT3)
   05207 Chemical carcinogenesis - receptor activation
    105099264 (AKT3)
   05208 Chemical carcinogenesis - reactive oxygen species
    105099264 (AKT3)
   05230 Central carbon metabolism in cancer
    105099264 (AKT3)
   05231 Choline metabolism in cancer
    105099264 (AKT3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    105099264 (AKT3)
  09162 Cancer: specific types
   05210 Colorectal cancer
    105099264 (AKT3)
   05212 Pancreatic cancer
    105099264 (AKT3)
   05225 Hepatocellular carcinoma
    105099264 (AKT3)
   05226 Gastric cancer
    105099264 (AKT3)
   05214 Glioma
    105099264 (AKT3)
   05221 Acute myeloid leukemia
    105099264 (AKT3)
   05220 Chronic myeloid leukemia
    105099264 (AKT3)
   05218 Melanoma
    105099264 (AKT3)
   05211 Renal cell carcinoma
    105099264 (AKT3)
   05215 Prostate cancer
    105099264 (AKT3)
   05213 Endometrial cancer
    105099264 (AKT3)
   05224 Breast cancer
    105099264 (AKT3)
   05222 Small cell lung cancer
    105099264 (AKT3)
   05223 Non-small cell lung cancer
    105099264 (AKT3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    105099264 (AKT3)
   05170 Human immunodeficiency virus 1 infection
    105099264 (AKT3)
   05161 Hepatitis B
    105099264 (AKT3)
   05160 Hepatitis C
    105099264 (AKT3)
   05164 Influenza A
    105099264 (AKT3)
   05162 Measles
    105099264 (AKT3)
   05168 Herpes simplex virus 1 infection
    105099264 (AKT3)
   05163 Human cytomegalovirus infection
    105099264 (AKT3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105099264 (AKT3)
   05169 Epstein-Barr virus infection
    105099264 (AKT3)
   05165 Human papillomavirus infection
    105099264 (AKT3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    105099264 (AKT3)
   05135 Yersinia infection
    105099264 (AKT3)
   05152 Tuberculosis
    105099264 (AKT3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    105099264 (AKT3)
   05142 Chagas disease
    105099264 (AKT3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    105099264 (AKT3)
   05017 Spinocerebellar ataxia
    105099264 (AKT3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105099264 (AKT3)
   05418 Fluid shear stress and atherosclerosis
    105099264 (AKT3)
   05415 Diabetic cardiomyopathy
    105099264 (AKT3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    105099264 (AKT3)
   04932 Non-alcoholic fatty liver disease
    105099264 (AKT3)
   04931 Insulin resistance
    105099264 (AKT3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    105099264 (AKT3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    105099264 (AKT3)
   01524 Platinum drug resistance
    105099264 (AKT3)
   01522 Endocrine resistance
    105099264 (AKT3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cdk01001]
    105099264 (AKT3)
Enzymes [BR:cdk01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     105099264 (AKT3)
Protein kinases [BR:cdk01001]
 Serine/threonine kinases: AGC group
  AKT/PKB family
   105099264 (AKT3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PH Pkinase_C Kinase-like PH_20 FTA2 ABC1 PH_11
Other DBs
NCBI-GeneID: 105099264
NCBI-ProteinID: XP_010990363
Position
23:20703234..20897848
AA seq 479 aa
MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
PFKPQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMDCMDNERRPHFPQFSYSASGRE
NT seq 1440 nt   +upstreamnt  +downstreamnt
atgagcgatgttaccattgtgaaagaaggttgggttcagaagaggggagaatatataaaa
aactggaggccaagatatttccttttgaagacagatggctcattcataggatataaagag
aaaccccaagatgtggatttaccttatcccctcaacaacttttcagtggcaaaatgccag
ttaatgaaaacagaacgaccaaagccaaacacatttattatcagatgtctccagtggacc
actgttatagagagaacatttcatgtagatactccagaggaaagggaagaatggacagaa
gctattcaggctgtagcagacagacttcagaggcaagaagaagagagaatgaattgtagt
ccaacttcacaaattgataatataggggaggaagagatggatgcttctacaactcatcat
aaaagaaagacaatgaatgattttgactatttgaaactgctaggtaaaggcacttttggg
aaagttattttggttcgagagaaggcaagtgggaaatactatgctatgaagattctgaag
aaagaagttattattgccaaggatgaagtggcacacactttaactgaaagcagagtatta
aagaacactagacatccctttttaacatccttgaaatactccttccagacaaaagaccgt
ttgtgttttgtgatggaatatgttaatggcggagagctgtttttccatttgtcgagagag
cgggtgttctctgaggaccgcacacgtttctatggtgcagaaattgtctctgccttggac
tatctacattccggaaagattgtgtaccgtgatctcaagttggagaatttgatgctggat
aaagatggccacataaaaattacagattttggactttgcaaagaagggatcacagatgca
gccaccatgaagacgttctgtggcacaccagagtatctggcaccagaggtgttagaagat
aatgactatggccgagccgtggattggtggggccttggggttgttatgtatgaaatgatg
tgtgggcggttgcccttctacaaccaggatcatgagaaactttttgaactaattctaatg
gaagacattaaatttcctcgaacactctcttcagatgcaaaatcattgctttcagggctc
ttgataaaggatccaaataaacgccttggtggaggaccagatgatgcaaaagaaattatg
agacacagtttcttttctggagtaaactggcaagatgtatatgataaaaagcttgtacct
ccttttaaacctcaagtaacatcagagacagacaccagatattttgatgaagaatttaca
gctcagactattacaataacaccaccagaaaaatatgatgaggacggcatggactgcatg
gacaatgagagacggccgcacttccctcagttttcctactctgcaagtggccgggaatag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (100)   
   KEGG PATHWAY (100)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (10)   
   RefSeq(pep) (10)   
DNA sequence (14)   
   RefSeq(nuc) (10)   
   GenBank (2)   
   EMBL (2)   
Protein domain (9)   
   Pfam (9)   
All databases (142)   

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