KEGG   Camelus dromedarius (Arabian camel): 105100330
Entry
105100330         CDS       T04642                                 
Symbol
CDK4
Name
(RefSeq) cyclin-dependent kinase 4
  KO
K02089  cyclin-dependent kinase 4 [EC:2.7.11.22]
Organism
cdk  Camelus dromedarius (Arabian camel)
Pathway
cdk01522  Endocrine resistance
cdk04110  Cell cycle
cdk04115  p53 signaling pathway
cdk04151  PI3K-Akt signaling pathway
cdk04218  Cellular senescence
cdk04530  Tight junction
cdk04660  T cell receptor signaling pathway
cdk04933  AGE-RAGE signaling pathway in diabetic complications
cdk04934  Cushing syndrome
cdk05160  Hepatitis C
cdk05162  Measles
cdk05163  Human cytomegalovirus infection
cdk05164  Influenza A
cdk05165  Human papillomavirus infection
cdk05166  Human T-cell leukemia virus 1 infection
cdk05167  Kaposi sarcoma-associated herpesvirus infection
cdk05169  Epstein-Barr virus infection
cdk05200  Pathways in cancer
cdk05203  Viral carcinogenesis
cdk05212  Pancreatic cancer
cdk05214  Glioma
cdk05218  Melanoma
cdk05219  Bladder cancer
cdk05220  Chronic myeloid leukemia
cdk05222  Small cell lung cancer
cdk05223  Non-small cell lung cancer
cdk05224  Breast cancer
cdk05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:cdk00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    105100330 (CDK4)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    105100330 (CDK4)
   04115 p53 signaling pathway
    105100330 (CDK4)
   04218 Cellular senescence
    105100330 (CDK4)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    105100330 (CDK4)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    105100330 (CDK4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105100330 (CDK4)
   05203 Viral carcinogenesis
    105100330 (CDK4)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    105100330 (CDK4)
   05225 Hepatocellular carcinoma
    105100330 (CDK4)
   05214 Glioma
    105100330 (CDK4)
   05220 Chronic myeloid leukemia
    105100330 (CDK4)
   05218 Melanoma
    105100330 (CDK4)
   05219 Bladder cancer
    105100330 (CDK4)
   05224 Breast cancer
    105100330 (CDK4)
   05222 Small cell lung cancer
    105100330 (CDK4)
   05223 Non-small cell lung cancer
    105100330 (CDK4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    105100330 (CDK4)
   05160 Hepatitis C
    105100330 (CDK4)
   05164 Influenza A
    105100330 (CDK4)
   05162 Measles
    105100330 (CDK4)
   05163 Human cytomegalovirus infection
    105100330 (CDK4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105100330 (CDK4)
   05169 Epstein-Barr virus infection
    105100330 (CDK4)
   05165 Human papillomavirus infection
    105100330 (CDK4)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    105100330 (CDK4)
   04934 Cushing syndrome
    105100330 (CDK4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    105100330 (CDK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cdk01001]
    105100330 (CDK4)
Enzymes [BR:cdk01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     105100330 (CDK4)
Protein kinases [BR:cdk01001]
 Serine/threonine kinases: CMGC group
  CDK family
   105100330 (CDK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH Kdo ABC1 Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 105100330
NCBI-ProteinID: XP_010991624
Position
12:complement(1016085..1018979)
AA seq 303 aa
MTTPRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGSGGGLPISTVREVALL
RRLEAFEHPNVVRLMDVCATARTDRETKVTLVFEHVDQDLRTYLDKAPPPGLPVETIKDL
MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR
DVSLPRGAFSPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKAEG
NPE
NT seq 912 nt   +upstreamnt  +downstreamnt
atgactacccctcgatatgagccagtggctgagattggtgttggtgcctatgggacggtg
tacaaagcccgtgatccccacagtggccactttgtggccctcaagagcgttagagttccc
aatggaggaggctctggagggggcctgcccatcagcacagttcgtgaggtggccttactg
cggcgcctggaggcttttgagcatcccaatgttgtacggctgatggacgtctgtgccaca
gcccgaactgaccgggaaaccaaagtgaccctggtatttgagcatgtggaccaagaccta
aggacatatctggacaaggcacccccaccaggcttgccagtggagaccatcaaggatctg
atgcgccagttcctaagaggcctagatttccttcatgccaactgcattgttcaccgagac
ctgaagccagagaacattctggtgacgagtggtgggacagtcaagctggctgactttggc
ctggccaggatctacagctaccagatggcacttacacctgtggtggttacactctggtac
cgtgctccggaagttcttctgcagtctacgtatgcaacacctgtggacatgtggagcgtt
ggctgtatctttgcagagatgtttcgtcgaaagcctctgttctgtggaaactctgaagct
gaccagttaggcaaaatctttgacctgattgggctgcccccagaggatgactggccccga
gatgtgtctctgccccgaggagccttttcccccagaggaccgcgcccagtgcagtcagtg
gttcctgagatggaggagtctggagcacagctgctgctggagatgctgacttttaaccca
cacaagcgaatctctgccttccgagccctgcagcactcttatctacataaggcagaaggt
aacccagagtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (28)   
   KEGG PATHWAY (28)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (6)   
   RefSeq(nuc) (2)   
   GenBank (2)   
   EMBL (2)   
Protein domain (7)   
   Pfam (7)   
All databases (52)   

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