KEGG   Caenorhabditis elegans (nematode): CELE_B0218.3Help
Entry
CELE_B0218.3      CDS       T00019                                 

Gene name
pmk-1
Definition
(RefSeq) Mitogen-activated protein kinase pmk-1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
cel  Caenorhabditis elegans (nematode)
Pathway
cel04010  MAPK signaling pathway
cel04068  FoxO signaling pathway
cel04212  Longevity regulating pathway - worm
cel04933  AGE-RAGE signaling pathway in diabetic complications
Module
cel_M00689  MAPK (p38) signaling
Brite
KEGG Orthology (KO) [BR:cel00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    CELE_B0218.3 (pmk-1)
   04068 FoxO signaling pathway
    CELE_B0218.3 (pmk-1)
 Organismal Systems
  Aging
   04212 Longevity regulating pathway - worm
    CELE_B0218.3 (pmk-1)
 Human Diseases
  Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    CELE_B0218.3 (pmk-1)
Enzymes [BR:cel01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     CELE_B0218.3 (pmk-1)
Protein kinases [BR:cel01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   CELE_B0218.3 (pmk-1)
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif
Pfam: Pkinase Pkinase_Tyr Kinase-like Kdo APH Haspin_kinase NAD_Gly3P_dh_N NAD_binding_8
Motif
Other DBs
NCBI-GeneID: 191743
NCBI-ProteinID: NP_501365
WormBase: WBGene00004055
Ensembl: WBGene00004055
UniProt: Q17446
Position
IV:join(8148806..8148954,8148999..8149564,8149932..8150296,8150688..8150741)
Genome map
AA seq 377 aa AA seqDB search
MFPQTTMDHILHPTPREGYYVVELNRSVWVVPNYYINLTPIGTGAYGTVCAAECTRSGTR
VAIKKFNRPFQSIIHARRTYRELRLLRCMCHENIIDLLDVFTPNENVNDIEDVYFVSMLM
GADLSNILKIQRLNDDHIQFLVYQILRGLKYIHSADIIHRDLKPSNIAVNEDCELKILDF
GLARQTDSEMTGYVATRWYRAPEIMLNWMHYTQTVDVWSVGCILAELITGKTLFPGSDHI
DQLTRIMSVTGTPDEEFLKKISSEEARNYIRNLPKMTRRDFKRLFAQATPQAIDLLEKML
HLDPDRRPTAKEAMEHEYLAAYHDETDEPIAEEMDLNDDVRADTIDEWKKIIWEEISDFQ
KNVAFADEEEDEEKMES
NT seq 1134 nt NT seq  +upstreamnt  +downstreamnt
atgtttccacagacaacaatggatcatatacttcatccgactccacgagaaggatactat
gtcgttgagcttaatcgaagtgtctgggttgttccaaattattatattaacttgactcca
attggtaccggagcatatggaactgtttgtgctgctgaatgtactcgctcggggactcgc
gtcgcaatcaaaaaattcaatcgtccatttcaatcaataattcatgcccgtcgtacatat
cgtgaactccgacttcttcgttgtatgtgtcatgaaaatataattgatctacttgatgtc
ttcactccaaatgagaatgtaaatgatatcgaggatgtgtattttgtatcaatgttgatg
ggagctgatctatcaaatattctcaaaattcagcgactcaacgatgaccacattcaattc
ttagtctatcaaattcttcgtggactcaaatacattcattctgcagatattattcatcga
gatcttaaaccatcaaatattgctgttaatgaggattgtgaattgaaaattcttgatttt
ggattggcacgtcaaactgattctgaaatgactggatacgtggcaacaagatggtacaga
gctccagagattatgctcaattggatgcattacacgcagactgttgatgtatggtcagtt
gggtgtattcttgcagaacttatcactggaaaaacattgttccctggatctgatcacatc
gatcaattgactcgtatcatgtcagtaactggaacaccagatgaagaattccttaaaaag
atctcatcagaagaagctcgtaattacattcgaaatcttccaaaaatgactcgccgtgat
ttcaaacgtctgtttgctcaagcaactcctcaagcaatcgatctccttgaaaagatgctt
caccttgatccagatcgtcgtccaactgcaaaagaagctatggagcatgaatatctggct
gcttatcacgatgaaactgatgagccaattgcagaagaaatggatttgaatgatgatgta
agggcagatacaattgatgaatggaagaaaattatttgggaagagatcagtgatttccag
aaaaacgtggcatttgctgacgaagaggaagatgaggagaaaatggaatcgtag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (26)   
   KEGG ORTHOLOGY (1)   
   RefGene (19)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   UniGene (1)   
   Ensembl (1)   
   OC (1)   
   WORMBASE (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (8)   
   Pfam (8)   
All databases (48)   

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