KEGG   Caenorhabditis elegans (nematode): CELE_B0334.8
Entry
CELE_B0334.8      CDS       T00019                                 
Symbol
age-1
Name
(RefSeq) Phosphatidylinositol 3-kinase age-1
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
cel  Caenorhabditis elegans (nematode)
Pathway
cel00562  Inositol phosphate metabolism
cel01100  Metabolic pathways
cel04012  ErbB signaling pathway
cel04068  FoxO signaling pathway
cel04070  Phosphatidylinositol signaling system
cel04140  Autophagy - animal
cel04150  mTOR signaling pathway
cel04212  Longevity regulating pathway - worm
cel04213  Longevity regulating pathway - multiple species
cel04361  Axon regeneration
Brite
KEGG Orthology (KO) [BR:cel00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    CELE_B0334.8 (age-1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    CELE_B0334.8 (age-1)
   04068 FoxO signaling pathway
    CELE_B0334.8 (age-1)
   04070 Phosphatidylinositol signaling system
    CELE_B0334.8 (age-1)
   04150 mTOR signaling pathway
    CELE_B0334.8 (age-1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    CELE_B0334.8 (age-1)
 09150 Organismal Systems
  09158 Development and regeneration
   04361 Axon regeneration
    CELE_B0334.8 (age-1)
  09149 Aging
   04212 Longevity regulating pathway - worm
    CELE_B0334.8 (age-1)
   04213 Longevity regulating pathway - multiple species
    CELE_B0334.8 (age-1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:cel04131]
    CELE_B0334.8 (age-1)
Enzymes [BR:cel01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     CELE_B0334.8 (age-1)
Membrane trafficking [BR:cel04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    CELE_B0334.8 (age-1)
SSDB
Motif
Pfam: PI3_PI4_kinase PI3K_C2 PI3Ka PI3K_rbd PI3K_p85B
Other DBs
NCBI-GeneID: 174762
NCBI-ProteinID: NP_496462
WormBase: WBGene00000090
UniProt: Q94125
Position
II:complement(<11519328..>11527054)
AA seq 1182 aa
MSMGRSPSTTFRSRTGSHGARDLIAGHGRNSRRISQMHVNILHPQLQTMVEQWQMRERPS
LETENGKGSLLLENEGVADIITMCPFGEVISVVFPWFLANVRTSLEIKLSDFKHQLFELI
APMKWGTYSVKPQDYVFRQLNNFGEIEVIFNDDQPLSKLELHGTFPMLFLYQPDGINRDK
ELMSDISHCLGYSLDKLEESLDEELRQFRASLWARTKKTCLTRGLEGTSHYAFPEEQYLC
VGESCPKDLESKVKAAKLSYQMFWRKRKAEINGVCEKMMKIQIEFNPNETPKSLLHTFLY
EMRKLDVYDTDDPADEGWFLQLAGRTTFVTNPDVKLTSYDGVRSELESYRCPGFVVRRQS
LVLKDYCRPKPLYEPHYVRAHERKLALDVLSVSIDSTPKQSKNSDMVMTDFRPTASLKQV
SLWDLDANLMIRPVNISGFDFPADVDMYVRIEFSVYVGTLTLASKSTTKVNAQFAKWNKE
MYTFDLYMKDMPPSAVLSIRVLYGKVKLKSEEFEVGWVNMSLTDWRDELRQGQFLFHLWA
PEPTANRSRIGENGARIGTNAAVTIEISSYGGRVRMPSQGQYTYLVKHRSTWTETLNIMG
DDYESCIRDPGYKKLQMLVKKHESGIVLEEDEQRHVWMWRRYIQKQEPDLLIVLSELAFV
WTDRENFSELYVMLEKWKPPSVAAALTLLGKRCTDRVIRKFAVEKLNEQLSPVTFHLFIL
PLIQALKYEPRAQSEVGMMLLTRALCDYRIGHRLFWLLRAEIARLRDCDLKSEEYRRISL
LMEAYLRGNEEHIKIITRQVDMVDELTRISTLVKGMPKDVATMKLRDELRSISHKMENMD
SPLDPVYKLGEMIIDKAIVLGSAKRPLMLHWKNKNPKSDLHLPFCAMIFKNGDDLRQDML
VLQVLEVMDNIWKAANIDCCLNPYAVLPMGEMIGIIEVVPNCKTIFEIQVGTGFMNTAVR
SIDPSFMNKWIRKQCGIEDEKKKSKKDSTKNPIEKKIDNTQAMKKYFESVDRFLYSCVGY
SVATYIMGIKDRHSDNLMLTEDGKYFHIDFGHILGHGKTKLGIQRDRQPFILTEHFMTVI
RSGKSVDGNSHELQKFKTLCVEAYEVMWNNRDLFVSLFTLMLGMELPELSTKADLDHLKK
TLFCNGESKEEARKFFAGIYEEAFNGSWSTKTNWLFHAVKHY
NT seq 3549 nt   +upstreamnt  +downstreamnt
atgtctatgggacgaagcccctccacgacatttcgaagtcgaaccggaagccatggagct
cgagatctgattgctggacacggacggaactcccgacgtatctcgcagatgcatgttaac
attttacatccacaactgcaaacgatggtcgagcagtggcaaatgcgagaacgcccatcg
ctggagaccgagaatggcaaaggatcgctgctcctggaaaatgaaggtgtcgcagatatc
atcactatgtgtccattcggagaagttattagtgtagtatttccgtggtttcttgcaaat
gtgcgaacatcgctagaaatcaagctatcagatttcaaacatcaacttttcgaattgatt
gctccgatgaagtggggaacatattccgtaaagccacaggattatgtgttcagacagttg
aataatttcggcgaaattgaagttatatttaacgacgatcaacccctgtcgaaattagag
ctccacggcactttcccaatgctttttctctaccaacctgatggaataaacagggataaa
gaattaatgagtgatataagtcattgtctaggatactcactggataaactggaagagagc
ctcgatgaggaactccgtcaatttcgtgcttctctctgggctcgtacgaagaaaacgtgc
ttgacacgtggacttgagggtaccagtcactacgcgttccccgaagaacagtacttgtgt
gttggtgaatcgtgcccgaaagatttggaatcaaaagtcaaggctgccaagctgagttat
cagatgttttggagaaaacgtaaagcggaaatcaatggagtttgcgagaaaatgatgaag
attcaaattgaattcaatccgaacgaaactccgaaatctctgcttcacacgtttctctac
gaaatgcgaaaattggatgtatacgataccgatgatcctgcagatgaaggatggtttctt
caattggctggacgtaccacgtttgttacaaatccagatgtcaaacttacgtcttatgat
ggtgtccgttcggaactggaaagctatcgatgccctggattcgttgttcgccgacaatca
ctagtcctcaaagactattgtcgcccaaaaccactctacgaaccacattatgtgagagca
cacgaacgaaaacttgctctagacgtgctcagcgtgtctatagatagcacaccaaaacag
agcaagaacagtgacatggttatgactgattttcgtccgacagcttcactcaaacaagtt
tcactttgggaccttgacgcgaatcttatgatacggcctgtgaatatttctggattcgat
ttcccggccgacgtggatatgtacgttcgaatcgaattcagtgtatatgtggggacactg
acgctggcatcaaaatctacaacaaaagtgaatgctcaatttgcaaaatggaataaggaa
atgtacacttttgatctatacatgaaggatatgccaccatctgcagtactcagcattcgt
gttttgtacggaaaagtgaaattaaaaagtgaagaattcgaagttggttgggtaaatatg
tccctaaccgattggagagatgaactacgacaaggacaatttttattccatctgtgggct
cctgaaccgactgccaatcgtagtaggatcggagaaaatggagcaaggataggcaccaac
gcagcggttacaattgaaatctcaagttatggtggtagagttcgaatgccgagtcaagga
caatacacatatctcgtcaagcaccgaagtacttggacggaaactttgaatattatgggt
gatgactatgagtcgtgtatcagagatccaggatataagaagcttcagatgcttgtcaag
aagcatgaatctggaattgtattagaggaagatgaacaacgtcatgtctggatgtggagg
agatacattcaaaagcaggagcctgatttgctcattgtgctctccgaactcgcatttgtg
tggactgatcgtgagaacttttccgagctctatgtgatgcttgaaaaatggaaaccgccg
agtgtggcagccgcgttgactttgcttggaaaacgttgcacggatcgtgtgattcgaaag
tttgcagtggagaagttgaatgagcagctgagcccggtcacattccatcttttcatattg
cctctcatacaggcgttgaagtacgaaccgcgtgctcaatcggaagttggaatgatgctc
ttgactagagctctctgcgattatcgaattggacatcgacttttctggctgctccgtgca
gagattgctcgtttgagagattgtgatctgaaaagtgaagaatatcgccgtatctcactt
ctgatggaagcttacctccgtggaaatgaagagcacatcaagatcatcacccgacaagtt
gacatggttgatgagctcacacgaatcagcactcttgtcaaaggaatgccaaaagatgtt
gctacgatgaaactgcgtgacgagcttcgatcgattagtcataaaatggaaaatatggat
tctccactggatcctgtgtacaaactgggtgaaatgataatcgacaaagccatcgtccta
ggaagtgcaaaacgtccgttaatgcttcactggaagaacaaaaatccaaagagtgacctg
caccttccgttctgtgcaatgatcttcaagaatggagacgatcttcgccaggacatgctt
gttcttcaagttctcgaagttatggataacatctggaaggctgcaaacattgattgctgt
ttgaacccgtacgcagttcttccaatgggagaaatgattggaattattgaagttgtgcct
aattgtaaaacaatattcgagattcaagttggaacaggattcatgaatacagcagttcgg
agtattgatccttcgtttatgaataagtggattcggaaacaatgcggaattgaagatgaa
aagaagaaaagcaaaaaggactctacgaaaaatcccatcgaaaagaagattgataatact
caagccatgaagaaatattttgaaagtgtcgatcgattcctatactcgtgtgttggatat
tcagttgccacgtacataatgggaatcaaggatcgtcacagtgataatctgatgctcact
gaagatggaaaatatttccacattgatttcggtcacattttgggacacggaaagaccaaa
cttgggatccagcgagatcgtcaaccgtttattctaaccgaacactttatgacagtgatt
cgatcgggtaaatctgtggatggaaattcgcatgagctacaaaaattcaaaacgttatgc
gtcgaagcctacgaagtaatgtggaataatcgagatttgttcgtttccttgttcaccttg
atgctcggaatggagttgcctgagctgtcgacgaaagcggatttggatcatttgaagaaa
accctcttctgcaatggagaaagcaaagaagaagcgagaaagtttttcgctggaatctac
gaagaagccttcaatggatcatggtctaccaaaacgaattggctcttccacgcagtcaaa
cactactga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (10)   
   KEGG PATHWAY (10)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (32)   
   KEGG ORTHOLOGY (1)   
   RefGene (27)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
   WORMBASE (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (5)   
   Pfam (5)   
All databases (63)   

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