KEGG   Caenorhabditis elegans (nematode): CELE_C12D8.10Help
Entry
CELE_C12D8.10     CDS       T00019                                 

Gene name
akt-1
Definition
(RefSeq) Serine/threonine-protein kinase akt-1
  KO
K04456  RAC serine/threonine-protein kinase [EC:2.7.11.1]
Organism
cel  Caenorhabditis elegans (nematode)
Pathway
cel04010  MAPK signaling pathway
cel04012  ErbB signaling pathway
cel04068  FoxO signaling pathway
cel04140  Autophagy - animal
cel04150  mTOR signaling pathway
cel04212  Longevity regulating pathway - worm
cel04213  Longevity regulating pathway - multiple species
cel04933  AGE-RAGE signaling pathway in diabetic complications
Module
cel_M00676  PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:cel00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    CELE_C12D8.10 (akt-1)
   04012 ErbB signaling pathway
    CELE_C12D8.10 (akt-1)
   04068 FoxO signaling pathway
    CELE_C12D8.10 (akt-1)
   04150 mTOR signaling pathway
    CELE_C12D8.10 (akt-1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    CELE_C12D8.10 (akt-1)
 09150 Organismal Systems
  09149 Aging
   04212 Longevity regulating pathway - worm
    CELE_C12D8.10 (akt-1)
   04213 Longevity regulating pathway - multiple species
    CELE_C12D8.10 (akt-1)
 09160 Human Diseases
  09167 Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    CELE_C12D8.10 (akt-1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cel01001]
    CELE_C12D8.10 (akt-1)
Enzymes [BR:cel01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     CELE_C12D8.10 (akt-1)
Protein kinases [BR:cel01001]
 Serine/threonine kinases: AGC group
  AKT/PKB family
   CELE_C12D8.10 (akt-1)
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif
Pfam: Pkinase Pkinase_Tyr PH Pkinase_C Kinase-like Haspin_kinase PH_11 KNTase_C
Motif
Other DBs
NCBI-GeneID: 179424
NCBI-ProteinID: NP_001023645
WormBase: WBGene00000102
Ensembl: WBGene00000102
UniProt: Q17941
Position
V:join(10248956..10249059,10249855..10249963,10250038..10250226,10250272..10250433,10250479..10250676,10250841..10251032,10251677..10251805,10251853..10252215,10252272..10252451)
Genome map
AA seq 541 aa AA seqDB search
MSMTSLSTKSRRQEDVVIEGWLHKKGEHIRNWRPRYFMIFNDGALLGFRAKPKEGQPFPE
PLNDFMIKDAATMLFEKPRPNMFMVRCLQWTTVIERTFYAESAEVRQRWIHAIESISKKY
KGTNANPQEELMETNQQPKIDEDSEFAGAAHAIMGQPSSGHGDNCSIDFRASMISIADTS
EAAKRDKITMEDFDFLKVLGKGTFGKVILCKEKRTQKLYAIKILKKDVIIAREEVAHTLT
ENRVLQRCKHPFLTELKYSFQEQHYLCFVMQFANGGELFTHVRKCGTFSEPRARFYGAEI
VLALGYLHRCDIVYRDMKLENLLLDKDGHIKIADFGLCKEEISFGDKTSTFCGTPEYLAP
EVLDDHDYGRCVDWWGVGVVMYEMMCGRLPFYSKDHNKLFELIMAGDLRFPSKLSQEART
LLTGLLVKDPTQRLGGGPEDALEICRADFFRTVDWEATYRKEIEPPYKPNVQSETDTSYF
DNEFTSQPVQLTPPSRSGALATVDEQEEMQSNFTQFSFHNVMGSINRIHEASEDNEDYDM
G
NT seq 1626 nt NT seq  +upstreamnt  +downstreamnt
atgtcgatgacaagcttgtcaacgaagtctcgaagacaagaagatgttgtcattgaggga
tggcttcacaagaaaggagagcacattcgaaactggagaccaagatacttcatgatattc
aatgatggagccttacttggatttcgagcaaagcctaaggaaggacaaccgtttcctgag
ccattgaatgattttatgatcaaggatgcagcgacaatgttattcgaaaaaccacgacct
aacatgttcatggtaagatgccttcagtggacaactgtcattgagcgaacattctatgcg
gagtcggcagaagttcgtcagcgttggattcatgctattgagagcatttcaaaaaaatac
aaaggcacaaatgcaaatccacaagaggaattaatggaaaccaatcagcagccaaaaatt
gatgaagacagtgaatttgctggtgcagcgcatgcaattatgggtcaaccatcttcggga
cacggtgataattgttcaattgacttcagagcgtctatgattagtattgctgacaccagc
gaagctgctaaaagagacaaaatcacaatggaagatttcgattttctcaaagtgctcggt
aaaggaacattcggaaaagttatcttgtgcaaggaaaagcgtactcaaaagctttatgcc
atcaaaattctcaaaaaagatgtaatcattgctcgcgaagaagttgctcacactttgaca
gaaaatcgagttcttcaaagatgcaagcatccgttccttacggaactgaaatatagtttc
caagagcaacactatctttgttttgtgatgcagtttgcgaatggtggagaactttttacg
catgtacgtaaatgtggaacatttagtgaaccaagagcccgattctacggagccgagatc
gttcttgctctcggataccttcaccgatgcgatattgtctaccgtgatatgaagcttgaa
aatttgcttcttgacaaagatggacatattaaaattgcggattttggattatgtaaagaa
gaaatcagttttggtgacaaaacaagtactttctgtggaactccggagtatcttgcacca
gaggttcttgatgatcatgactacggacgttgtgttgattggtggggagttggagttgtg
atgtacgagatgatgtgtggaaggcttccattttattcgaaggatcataataaactattc
gaacttatcatggctggtgatctaaggttcccaagcaagttgagtcaagaagctagaact
ttgctcaccggacttcttgtcaaagatccaactcagcgattgggtggtggacccgaagat
gcattggagatttgtagagcagactttttccgtactgtcgattgggaagcaacgtacaga
aaagaaatcgagccaccatataagccaaatgtgcagtcagaaactgatactagttacttt
gataatgaattcacatctcaaccagttcaactgacaccgcctagtagaagcggagccctt
gctacagtcgatgagcaagaagaaatgcaatcaaacttcacacaattctcattccacaat
gttatgggaagtatcaatcgaattcatgaagcaagtgaagacaacgaagattatgatatg
ggataa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (9)   
   KEGG PATHWAY (8)   
   KEGG MODULE (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (29)   
   KEGG ORTHOLOGY (1)   
   RefGene (22)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   UniGene (1)   
   Ensembl (1)   
   OC (1)   
   WORMBASE (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (7)   
   RefSeq(nuc) (3)   
   GenBank (2)   
   EMBL (2)   
Protein domain (8)   
   Pfam (8)   
All databases (63)   

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