KEGG   Caenorhabditis elegans (nematode): CELE_C12D8.10Help
Entry
CELE_C12D8.10     CDS       T00019                                 

Gene name
akt-1
Definition
(RefSeq) Serine/threonine-protein kinase akt-1
  KO
K04456  RAC serine/threonine-protein kinase [EC:2.7.11.1]
Organism
cel  Caenorhabditis elegans (nematode)
Pathway
cel04010  MAPK signaling pathway
cel04012  ErbB signaling pathway
cel04068  FoxO signaling pathway
cel04140  Autophagy - animal
cel04150  mTOR signaling pathway
cel04212  Longevity regulating pathway - worm
cel04213  Longevity regulating pathway - multiple species
cel04933  AGE-RAGE signaling pathway in diabetic complications
Module
cel_M00676  PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:cel00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    CELE_C12D8.10 (akt-1)
   04012 ErbB signaling pathway
    CELE_C12D8.10 (akt-1)
   04068 FoxO signaling pathway
    CELE_C12D8.10 (akt-1)
   04150 mTOR signaling pathway
    CELE_C12D8.10 (akt-1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    CELE_C12D8.10 (akt-1)
 09150 Organismal Systems
  09149 Aging
   04212 Longevity regulating pathway - worm
    CELE_C12D8.10 (akt-1)
   04213 Longevity regulating pathway - multiple species
    CELE_C12D8.10 (akt-1)
 09160 Human Diseases
  09167 Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    CELE_C12D8.10 (akt-1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cel01001]
    CELE_C12D8.10 (akt-1)
Enzymes [BR:cel01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     CELE_C12D8.10 (akt-1)
Protein kinases [BR:cel01001]
 Serine/threonine kinases: AGC group
  AKT/PKB family
   CELE_C12D8.10 (akt-1)
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif
Pfam: Pkinase Pkinase_Tyr PH Pkinase_C Kinase-like Haspin_kinase PH_11 KNTase_C
Motif
Other DBs
NCBI-GeneID: 179424
NCBI-ProteinID: NP_001023645
WormBase: WBGene00000102
Ensembl: WBGene00000102
UniProt: Q17941
Position
V:join(10248956..10249059,10249855..10249963,10250038..10250226,10250272..10250433,10250479..10250676,10250841..10251032,10251677..10251805,10251853..10252215,10252272..10252451)
Genome map
AA seq 541 aa AA seqDB search
MSMTSLSTKSRRQEDVVIEGWLHKKGEHIRNWRPRYFMIFNDGALLGFRAKPKEGQPFPE
PLNDFMIKDAATMLFEKPRPNMFMVRCLQWTTVIERTFYAESAEVRQRWIHAIESISKKY
KGTNANPQEELMETNQQPKIDEDSEFAGAAHAIMGQPSSGHGDNCSIDFRASMISIADTS
EAAKRDKITMEDFDFLKVLGKGTFGKVILCKEKRTQKLYAIKILKKDVIIAREEVAHTLT
ENRVLQRCKHPFLTELKYSFQEQHYLCFVMQFANGGELFTHVRKCGTFSEPRARFYGAEI
VLALGYLHRCDIVYRDMKLENLLLDKDGHIKIADFGLCKEEISFGDKTSTFCGTPEYLAP
EVLDDHDYGRCVDWWGVGVVMYEMMCGRLPFYSKDHNKLFELIMAGDLRFPSKLSQEART
LLTGLLVKDPTQRLGGGPEDALEICRADFFRTVDWEATYRKEIEPPYKPNVQSETDTSYF
DNEFTSQPVQLTPPSRSGALATVDEQEEMQSNFTQFSFHNVMGSINRIHEASEDNEDYDM
G
NT seq 1626 nt NT seq  +upstreamnt  +downstreamnt
atgtcgatgacaagcttgtcaacgaagtctcgaagacaagaagatgttgtcattgaggga
tggcttcacaagaaaggagagcacattcgaaactggagaccaagatacttcatgatattc
aatgatggagccttacttggatttcgagcaaagcctaaggaaggacaaccgtttcctgag
ccattgaatgattttatgatcaaggatgcagcgacaatgttattcgaaaaaccacgacct
aacatgttcatggtaagatgccttcagtggacaactgtcattgagcgaacattctatgcg
gagtcggcagaagttcgtcagcgttggattcatgctattgagagcatttcaaaaaaatac
aaaggcacaaatgcaaatccacaagaggaattaatggaaaccaatcagcagccaaaaatt
gatgaagacagtgaatttgctggtgcagcgcatgcaattatgggtcaaccatcttcggga
cacggtgataattgttcaattgacttcagagcgtctatgattagtattgctgacaccagc
gaagctgctaaaagagacaaaatcacaatggaagatttcgattttctcaaagtgctcggt
aaaggaacattcggaaaagttatcttgtgcaaggaaaagcgtactcaaaagctttatgcc
atcaaaattctcaaaaaagatgtaatcattgctcgcgaagaagttgctcacactttgaca
gaaaatcgagttcttcaaagatgcaagcatccgttccttacggaactgaaatatagtttc
caagagcaacactatctttgttttgtgatgcagtttgcgaatggtggagaactttttacg
catgtacgtaaatgtggaacatttagtgaaccaagagcccgattctacggagccgagatc
gttcttgctctcggataccttcaccgatgcgatattgtctaccgtgatatgaagcttgaa
aatttgcttcttgacaaagatggacatattaaaattgcggattttggattatgtaaagaa
gaaatcagttttggtgacaaaacaagtactttctgtggaactccggagtatcttgcacca
gaggttcttgatgatcatgactacggacgttgtgttgattggtggggagttggagttgtg
atgtacgagatgatgtgtggaaggcttccattttattcgaaggatcataataaactattc
gaacttatcatggctggtgatctaaggttcccaagcaagttgagtcaagaagctagaact
ttgctcaccggacttcttgtcaaagatccaactcagcgattgggtggtggacccgaagat
gcattggagatttgtagagcagactttttccgtactgtcgattgggaagcaacgtacaga
aaagaaatcgagccaccatataagccaaatgtgcagtcagaaactgatactagttacttt
gataatgaattcacatctcaaccagttcaactgacaccgcctagtagaagcggagccctt
gctacagtcgatgagcaagaagaaatgcaatcaaacttcacacaattctcattccacaat
gttatgggaagtatcaatcgaattcatgaagcaagtgaagacaacgaagattatgatatg
ggataa

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