KEGG   Canis lupus familiaris (dog): 100688870
Entry
100688870         CDS       T01007                                 
Symbol
CACNA2D2
Name
(RefSeq) voltage-dependent calcium channel subunit alpha-2/delta-2 isoform X1
  KO
K04859  voltage-dependent calcium channel alpha-2/delta-2
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa04010  MAPK signaling pathway
cfa04260  Cardiac muscle contraction
cfa04261  Adrenergic signaling in cardiomyocytes
cfa04921  Oxytocin signaling pathway
cfa05410  Hypertrophic cardiomyopathy
cfa05412  Arrhythmogenic right ventricular cardiomyopathy
cfa05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100688870 (CACNA2D2)
 09150 Organismal Systems
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    100688870 (CACNA2D2)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    100688870 (CACNA2D2)
   04261 Adrenergic signaling in cardiomyocytes
    100688870 (CACNA2D2)
 09160 Human Diseases
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    100688870 (CACNA2D2)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    100688870 (CACNA2D2)
   05414 Dilated cardiomyopathy
    100688870 (CACNA2D2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:cfa04040]
    100688870 (CACNA2D2)
Ion channels [BR:cfa04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   100688870 (CACNA2D2)
SSDB
Motif
Pfam: VGCC_alpha2 VWA_N VWA VWA_3 VWA_2 dCache_1 dCache_2 Cache_3-Cache_2 T6SS_FHA_C VWA_CoxE DUF5610
Other DBs
NCBI-GeneID: 100688870
NCBI-ProteinID: XP_038311737
Ensembl: ENSCAFG00000010431
VGNC: 38642
Position
20:38778136..38916454
AA seq 1155 aa
MAVPAWTCGASRPGPAPTALPWPGRGPRPGPGSRRPPSGPPRPLLLLLPPLLLLPLLAAP
GASAYSFPQQHTMQHWARRLEQEIDGVMRIFGGVQQLREIYKDNRNLFEVQENEPQKLVE
KVAGDIESLLDRKVRALKRLADAAENFQKAHRWQDNIKEEDILYYDAKADAELDDPESED
VERGSKVSTLRLDFVEDSNFKNKVNYSYTAVQIPTDIYKGSTVILNELNWTEALENVFIE
NRRQDPTLLWQVFGSATGVTRYYPATPWRAPKKIDLYDVRRRPWYIQGASSPKDMVIIVD
VSGSVSGLTLKLMKTSVCEMLDTLSDDDYVNVASFNEKAQPVSCFTHLVQANVRNKKVFK
EAVQGMVAKGTTGYKAGFEYAFDQLQNSNITRANCNKMIMMFTDGGEDRVQDVFEKYNWP
NRTVRVFTFSVGQHNYDVTPLQWMACANKGYYFEIPSIGAIRINTQEYLDVLGRPMVLAG
KEAKQVQWTNVYEDALGLGLVVTGTLPVFNLTQDGPGEKKNQLILGVMGIDVALNDIKRL
TPNYTLGANGYVFAIDLNGYVLLHPNLKPQTTNFREPVTLDFLDAELEDENKEEIRRSMI
DGNKGHKQIRTLVKSLDERYVDEVVRNYTWVPIRSTNYSLGLVLPPYSTFYLQANLSDQI
LQVKLPISKLKDFEFLLPSSFESEGHVFIAPREYCKDLNASDNNTEFLKNFIELMEKVTP
DSKQCNNFLLHNLILDTGITQQLVERVWRDQDLNTYSLLAVFAATDGGITRVFPNKAAED
WTENPEPFNASFYRRSLDNHGYIFKPPHQDALLRPLELENDTVGILVSTAVELSLGGRTL
RPAVVGVKLDLEAWAEKFKVLASNRTHQDQPQKCGPSSHCEMDCEVNNEDLLCVLIDDGG
FLVLSNQNHQWDQVGRFFSEVDANLMLALYNNSFYTRKESYDYQAACAPQPPGNLGAAPR
GVFVPTIADFLNLAWWTSAAAWSLFQQLLYGLIYHSWFQADSAEAEGSPEARESSCVMKQ
TQYYFGSVNASYNAIIDCGNCSRLFHAQRLTNTNLLFVVAEKPLCSQCEAGRLLQKETHC
PADGPEQCELVQRPRYRRGPHICFDYNATEDTSDCGRGASFPPSLGVLVSLQLLLLLGLP
PRPQPQVPAHASRRL
NT seq 3468 nt   +upstreamnt  +downstreamnt
atggcggtgccggcttggacctgcggcgcctctcggcccggcccggcgccgactgcgctc
ccctggcccggccgcggcccccggcccggccccggctcccggcgcccgccgtccgggccc
ccgcgcccgctgttgctgctgctgccgccgctgctgctgctgccgctgctcgccgccccc
ggcgcgtctgcctacagcttcccccagcagcacacgatgcagcactgggcccgacgcctg
gagcaagagattgatggcgtgatgcggatctttgggggtgtccagcagctccgtgagatc
tacaaggacaaccggaatctgtttgaggtgcaggagaacgagcctcagaagttggtggaa
aaggtggcaggagacattgagagcctgctggacaggaaggtgcgggccctgaagagactg
gccgatgctgccgagaacttccagaaagcccaccgctggcaggacaacatcaaggaggaa
gatatcctgtactatgacgccaaggctgacgctgagctggacgaccctgagagtgaggat
gtggagagggggtccaaggtcagcaccctaaggctggacttcgttgaggactcaaacttc
aagaacaaagtcaactattcgtacacggccgtgcagatccccacggacatctacaaaggc
tctactgtcatccttaacgaactcaactggacagaagccctggagaatgtgttcattgag
aatcgccggcaggaccccacgctgctgtggcaggtcttcggaagtgccacgggagtcact
cgctactacccagccaccccatggcgagcccccaagaaaatcgacctgtatgatgtccga
aggagaccctggtatatccagggggcctcatcacccaaggacatggtcatcatcgtggac
gtgagtggcagtgtgagcggcctgaccctgaagctgatgaagacgtccgtctgtgagatg
ctggacacgctctcagatgatgactatgtgaacgtggcctcgttcaatgaaaaggcacag
cctgtgtcatgcttcacacatctggtgcaggccaatgtgcgtaacaagaaggtgttcaag
gaagccgtgcagggcatggtggccaagggcaccacaggctacaaggccggctttgagtat
gccttcgaccagctgcagaactccaacatcactcgtgccaactgcaataagatgatcatg
atgttcacggacggtggtgaggaccgtgtgcaggatgtctttgagaagtacaattggccc
aaccggacggtgcgcgtgttcactttttccgtggggcagcacaactacgacgtcacaccc
ctgcagtggatggcctgcgccaacaaaggttactattttgagatcccttccattggagcc
atccgcattaacacgcaggaatatctggacgtactgggcaggcccatggtgctagctggc
aaggaggccaagcaggtgcaatggaccaacgtgtatgaggatgctctggggctgggattg
gtggtgacagggaccctccctgttttcaacctgacacaggatggccctggggagaaaaag
aaccagctgatcctgggtgtgatgggcatcgatgtggctctgaatgacatcaagaggctg
accccaaactacacacttggagccaacgggtacgtgtttgccattgacctgaatggctac
gtgttgctgcaccccaacctcaagccccagaccaccaacttccgagagcctgtgactctg
gacttcctggacgccgagctggaggatgagaacaaggaggagatccgtcggagcatgatt
gatggcaacaagggccacaagcagatcagaacactggtcaagtccctggacgagaggtac
gtagacgaggtggtgcggaactacacctgggtgcctataaggagcaccaactacagcctc
gggcttgtgctcccaccctacagcaccttctacctccaagccaacctcagcgaccagatc
ctgcaggtcaagttgccaatcagcaaactgaaggattttgagttcctgctccccagcagc
tttgagtctgaaggacatgttttcattgctcccagagagtattgcaaggacctgaatgcc
tcagacaacaacaccgagttcctgaaaaacttcattgagctcatggagaaagtgactcca
gactccaagcagtgcaacaactttcttctgcacaacctaatcttggacacgggcatcaca
cagcagctggtagagcgagtgtggcgggaccaagatctcaacacgtacagccttctggcc
gtgtttgctgccaccgacggcggcatcactcgcgttttccccaacaaagcagctgaggac
tggacggagaacccggagcccttcaatgccagcttctatcgccgtagcctggacaaccac
ggctatatcttcaaacccccacatcaggatgccctgttaaggccactggagctggagaat
gacacggtgggcatcctcgtcagcacagctgtggagctaagcctgggcgggcgcacactg
aggccagcagtggtaggtgttaagctggacctagaggcctgggctgagaagttcaaggtg
ctagccagcaaccgtacccaccaggaccagcctcagaagtgtggccctagcagccactgt
gagatggactgcgaggttaacaatgaggacctgctctgtgtcctcattgatgatggggga
ttcctggtgctgtcaaaccagaatcatcagtgggaccaggtgggcaggttcttcagtgag
gtggacgccaacctgatgctggcactctacaataactccttctacacccgcaaagagtcc
tacgattatcaggcagcctgcgccccccagccccctggcaacctgggtgctgcaccgcgg
ggcgtctttgtgcccaccattgcagacttccttaacctggcctggtggacctccgctgca
gcctggtccttgttccagcagctcctctatggcctcatctatcacagctggttccaggca
gactccgcggaggccgaggggagccccgaggcgcgcgagagcagctgcgtcatgaaacag
actcagtactacttcgggtcggtgaacgcctcctacaacgccatcatcgactgcggaaac
tgctccaggctgttccacgcgcagagactgaccaacaccaaccttctcttcgtggtggcc
gagaagccgctgtgcagccagtgtgaggctggccggctgctgcagaaggagacacactgc
ccagcggacggcccggagcagtgtgaactggtgcagagaccgcgataccggagaggcccg
cacatctgctttgactacaacgcgacggaagatacctcagactgcggccgcggagcttcc
ttcccgccgtcgctgggcgtcctggtctccctgcagctgctgctcctcctgggcctgcct
ccccggcctcagccccaagtccccgcccacgcctcgcgccgcctctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (7)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (12)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (35)   
   RefSeq(pep) (35)   
DNA sequence (35)   
   RefSeq(nuc) (35)   
Protein domain (11)   
   Pfam (11)   
All databases (109)   

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