KEGG   Canis lupus familiaris (dog): 478634
Entry
478634            CDS       T01007                                 
Symbol
SDHA
Name
(RefSeq) succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial isoform X1
  KO
K00234  succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa00020  Citrate cycle (TCA cycle)
cfa00190  Oxidative phosphorylation
cfa01100  Metabolic pathways
cfa01200  Carbon metabolism
cfa04714  Thermogenesis
cfa04932  Non-alcoholic fatty liver disease
cfa05010  Alzheimer disease
cfa05012  Parkinson disease
cfa05014  Amyotrophic lateral sclerosis
cfa05016  Huntington disease
cfa05020  Prion disease
cfa05022  Pathways of neurodegeneration - multiple diseases
cfa05208  Chemical carcinogenesis - reactive oxygen species
cfa05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    478634 (SDHA)
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    478634 (SDHA)
 09150 Organismal Systems
  09159 Environmental adaptation
   04714 Thermogenesis
    478634 (SDHA)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    478634 (SDHA)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    478634 (SDHA)
   05012 Parkinson disease
    478634 (SDHA)
   05014 Amyotrophic lateral sclerosis
    478634 (SDHA)
   05016 Huntington disease
    478634 (SDHA)
   05020 Prion disease
    478634 (SDHA)
   05022 Pathways of neurodegeneration - multiple diseases
    478634 (SDHA)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    478634 (SDHA)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    478634 (SDHA)
Enzymes [BR:cfa01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.5  With a quinone or related compound as acceptor
    1.3.5.1  succinate dehydrogenase
     478634 (SDHA)
SSDB
Motif
Pfam: FAD_binding_2 Succ_DH_flav_C Pyr_redox_2 Thi4 GIDA DAO FAD_binding_3 HI0933_like
Other DBs
NCBI-GeneID: 478634
NCBI-ProteinID: XP_013965792
Ensembl: ENSCAFG00000010951
VGNC: 45949
Position
34:complement(16448897..16478318)
AA seq 665 aa
MSGVRAVSRLLGARRLALTRAQWPAAWQTGTRSFHFTIDGNKRSSAKVSDSISTQYPVVD
HEFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNW
RWHFYDTVKGSDWLGDQDAIHYMTEQAPASVVELENYGMPFSRTEDGRIYQRAFGGQSLK
FGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCI
EDGSIHRIRAKNTVVATGGYGRTYFSCTSAHTSTGDGTAMVTRAGLPCQDLEFVQFHPTG
IYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGP
EKDHVYLQLHHLPPEQLAIRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKG
QVLRHVNGQDQIVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIAESCRPGD
KIPPIKPNAGEESVMNLDKLRFANGSVRTSELRLNMQKSMQSHAAVFRVGSVLQEGCEKI
SQLYGDLKHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKV
RIDEYDYSKPIQGQQKKPFEEHWRKHTLSYVDIKTGKVSLEYRPVIDRTLNEADCATVPP
AIRSY
NT seq 1998 nt   +upstreamnt  +downstreamnt
atgtcgggggtccgggcggtgtctcggctgctgggcgcccggcgcctggcgctgaccaga
gcacagtggccggcggcatggcagacaggcacccgcagttttcacttcaccattgatggg
aataagaggtcctctgctaaagtttcagattcaatctctacgcagtacccagtggtggac
catgaatttgatgcagtggtggtaggcgctggaggggcgggcttgcgagctgcatttggc
ctttcagaggctgggtttaacacggcctgcgtcacaaagctctttcccaccagatcacac
accgttgccgcccagggaggaatcaatgctgctctgggcaacatggaggaggacaactgg
aggtggcacttctacgacaccgtgaagggctccgactggctgggggaccaggacgccatc
cactacatgacagagcaggcccctgcttctgtggtagagctggagaattatggcatgcca
tttagcagaactgaagatggaaggatctatcagcgtgcttttggtggacagagcctcaag
tttgggaaaggcgggcaggcccatcggtgctgctgtgtggctgaccgcactggccactcg
ctgctgcacacgttgtatggaaggtctctgcgatatgataccagctattttgtagagtac
tttgccttggatctcttgatggaaaatggagaatgtcgtggtgttattgcactgtgcata
gaagatgggtccatccatcgcataagagccaagaacactgttgtggctaccggaggttat
gggcgcacctacttcagctgcacatctgcccacaccagcaccggtgacggcaccgccatg
gtcaccagggcaggccttccctgccaggacttggagttcgttcagttccaccccacaggt
atatatggtgctggttgtctcattacggaaggatgccgtggagagggaggcattctcatt
aacagtcaaggcgaaaggttcatggagcgatatgccccagtcgcaaaggacctggcatcc
agagacgttgtatctcggtccatgactctggaaatccgtgaaggcagaggctgtggcccc
gaaaaagaccatgtgtacctgcagttgcaccacctaccgcccgagcagttggccatacgt
ctgcctggcatttcagagacggccatgatctttgccggtgtggatgtcaccaaggagcca
atccccgtccttcccactgtgcattataacatgggtggcattcccaccaactacaagggg
caggttctgaggcacgtgaatggccaggatcagattgtgcctggcctgtatgcatgcggg
gaggccgcctgcgcctcggtgcacggtgccaaccgcctcggagccaactcgctcttggac
ttggtcgtctttggccgggcatgtgccctgagtatcgcagagtcctgcagacctggagat
aaaattcccccgattaaaccaaatgccggggaagagtctgtcatgaatcttgacaaactg
agatttgccaatggaagtgtaagaacatctgaactacgactcaacatgcagaagtcgatg
cagagtcatgctgctgtgttccgtgtgggaagtgtgttacaggaaggctgtgagaaaatc
agccagctctatggagacctaaagcatctgaagacatttgaccgaggaatggtctggaac
accgacctggtagagaccctggagctgcagaacctgatgctctgtgcacttcagaccatt
tatggagcagaggcccggaaggagtcacgtggcgctcacgccagggaagattacaaggtg
cggattgacgagtatgattactctaagcccatccagggacagcagaagaagccgtttgag
gagcactggagaaagcacaccctttcctacgtcgatatcaagactgggaaggtctcattg
gaatatagacctgtgatcgacagaactttaaatgaggctgactgtgccacggtccctcca
gccattcgctcctactga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (17)   
   KEGG PATHWAY (14)   
   KEGG MODULE (3)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (9)   
   RefSeq(pep) (9)   
DNA sequence (11)   
   RefSeq(nuc) (9)   
   GenBank (1)   
   EMBL (1)   
Protein domain (8)   
   Pfam (8)   
All databases (65)   

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