KEGG   Canis lupus familiaris (dog): 481963
Entry
481963            CDS       T01007                                 
Symbol
REV3L
Name
(RefSeq) DNA polymerase zeta catalytic subunit isoform X1
  KO
K02350  DNA polymerase zeta [EC:2.7.7.7]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa01524  Platinum drug resistance
cfa03460  Fanconi anemia pathway
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03460 Fanconi anemia pathway
    481963 (REV3L)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    481963 (REV3L)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:cfa03400]
    481963 (REV3L)
Enzymes [BR:cfa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.7  DNA-directed DNA polymerase
     481963 (REV3L)
DNA repair and recombination proteins [BR:cfa03400]
 Eukaryotic type
  TLS (translesion DNA synthesis) factors
   B-family DNA polymerases
    481963 (REV3L)
SSDB
Motif
Pfam: DUF4683 DNA_pol_B DNA_pol_B_exo1 zf-C4pol
Other DBs
NCBI-GeneID: 481963
NCBI-ProteinID: XP_013973691
Ensembl: ENSCAFG00000003942
VGNC: 45488
UniProt: A0A8C0MFV9
Position
12:complement(67596234..67773130)
AA seq 3137 aa
MFSVRIVTADYYMASPLRGLDTCLCPLTQAPVKKVPVVRVFGATPAGQKTCLHLHGIFPY
LYVPYDGYGQQPESYLSQMAFSIDRALNVALGNPSSTAQHVFKVSLVSGMPFYGYHEKEK
HFMKIYLYNPAMVKRICELLQSGAIMNKFYQPHEAHIPYLLQLFIDYNLYGMNLINLAAV
KFRKARRKSNQLHTTGSCKDRLPGNSLTGTLFRWEEDEIPSSLILEGVEPQSTCELEVDA
VAADILNRLDIEAQIGGNPGLQAIWEDEKQRRRNRNETSQINQPESQDRRFVPATESEKN
FQKRLQEILKQNDFSVRTLSGSVDYSDGSQEFSAELTLHSEVLSPDTLQCTPANMVEVHK
DTELGKGHAVYKVEEALINEEAILNLMENSQTFQPLTQRLSESPVFLDSSPDEALVRLLA
GLENDGYQGGRNRMPSPCHFFGNTKNPQNSDDEENEPQIEKEEMELSLVMSQRWDSNIEE
PCAKKRSLCRNTRRSSTEEDDSSSEEEMEWSNNSLLLANLSIPQLDGTADENSDNPLNNE
NSRTHSSVIATSKLSVKPSIFHKDAATLEPPSSAKITFQCKHTSALSSHVLNKEDLIEDL
PQPNNIEKCIDHSVASFTNESTYSMKYPGSLSSSVHSENSHKESSKKDILPVSSCESSIF
DYEEDIPSVPRQVPSRKYTNIRKIDKDTPFIHMNRHSSENTLGKNSFNFSDLSHPKNKLP
SEGNEKGNSTALNSLFPSSLTENCELLSCSGENRTMVHSLDSIADESGLNKLKIRYEEFQ
EHKTEKPSLSQQAAHYMFFPSVVLSNCLSRPQKLSPVTYKLQPSSKQSRLKINKKKLIGH
QETSTKTSETVSTKDNCIQNNPCNSNPEKDNVLASDLIKVTRGAFENKTPIDSFIDCHFG
DGTLETEQSFGLYGNKYTLRAKRKVNYETEDSESSFVTHNSKISLPHSMEIGESLDGTLK
SRKRRKMSKKLPPVIIKYIIINRFRGRKNMLVKLGKIDSKEKQVILTEEKMELYKKLAPL
KDFWPKVPDSPATKYPIYPLTPKKSHRRKSKHKSAKKKTGKQQRTNSENIKRTLSFRRKR
SHAILSPPSPSYNAETEDCDLNYSDVMSKLGFLSERSTSPINSSPPRCWSPTDPRAEEMM
AAVDKETMLFKGPNACINKTANSRVEKNSRARAQVKKSKTKLVNPSVVTKKRNKRNQTNK
VGDDGKKKPRAKQKQKTNEKGMSRKHITIKDEKIKSQPGAEVKFVLKHQNVSETSNSSGG
SQLLFKQKDVSLMGSTIDHPLSAPLPTGIHAQQNLSGCFSSFLESKKPVDLQTFPSSRDD
LHSSVVCSSLGPGISKINVQRSHNQSAMFTLKESTLIQKNIFDLSNHLSQVAQNTQISSG
ITSPKTEENANTQKNYLSSIGKLNEYRNSLESKPDQAYAPNFLHCKDSQQQIVCGSEQSK
HNETCSPGNAAAEESQMPNNCFVTSLRSPIKQIAWEQKQRGFILDMSNFKPERVKQRSLS
EAISQTKALSQCKSRNVSTPSAFGEGQSGLAVLKELLQKRQQKAQNANIMQDPLSNKHQP
NKNISGSLEQNKTVKRTRSVTSSRKPRTPRSTKPKEKIPKLIKVDSLNLQNSVQLDNSLS
DDSPIFFSDPGFESCYSLEDSLSPEHNYNFDINTIGQTGFCSFYSGSQFVPADQNLPQKF
LSDAVQDLFPGQAIEKNEFLSHDNQKCDEDKHHASDSTSWIRSSTLSPELFEKSSIDNNE
NHRHNQWKSSFHPLTTRSNSIMDSFCVQQAEDCLNEKSRLNRSSVSKEVFLSLSQPGTSD
WIQGHTRKEMQQSLDSVNTSFTTILSSPDGELVDAASEDLELYVSRNNDMLTPTPDSSPR
STSSPSQSKNGSFTPRTAHILKPLMSPPSREEIMATLLDHDLSETIYQEPFCSNPSDVPE
KPREIGGRLLMVETRLPNDLAEFEGDFSLEGLRLWKTAFSAMTQNPRPGSPLRNGQAVVN
KGSSNSSKMAEDKKIVIMPCKCAPSRQLVQAWLQAKEEYERSKKLSKNEPTGVVKSAENF
SSSVNPDDKPVVPPKMSTTPHILPTTAHTKEDVDNSQFALQAVTTGCSQTVSESQTLPPV
ASADDPEKGEDDDDDDNDDYYVSYSSPDSPVIPPWQQATSPDSKILNGDERPISPVKELH
SLNIENFLKPVKDGIQKSPSSEPLEPLVISPINVRARTGICESLCLHSTPIVQRKFLERL
PEASSLSPLSTEPKTQKLSHKKGSNTDTFRRILLTQAKNQFAAVNTPKKETSQIDGPSLN
NTYGFKVSVQNLQEAKALHEIQNLTLISVELHARTRRDLEPDPEFDPICALFYCISSDTP
LPDTDKTELTGVIVIDKDKTVSSQDIRYQTPLLIRSGITGLEVTYAPDEKALFQEIADII
KRYDPDILLGYEIQMHSWGYLLQRAAALSVDLGQMISRVPDDKIENRFAPERDDYGSETM
SEINIVGRITLNLWRIMRNEVALTNYTFENVSFHVLHQRFPLFTFRVLSDWFDNKTDLYR
WKMVDHYISRVRGNLQMLEQLDLIGKTSEMARLFGIQFLHVLTRGSQYRVESMMLRIAKP
MNYIPVTPSVQQRSQMRAPQCVPLIMEPESRFYSNSVLVLDFQSLYPSIVIAYNYCFSTC
LGHVENLGKYDEFKFGCTSLRVPPDLLYQIRHDITVSPNGIAFVKPSVRKGVLPRMLEEI
LKTRLMVKQSMKAYKQDRALSRMLDARQLGLKLIANVTFGYTAANFSGRMPCIEVGDSIV
HKARETLERAIKLVNDTKKWGARVVYGDTDSMFVLLKGATKEQSFKIGQEIAEAVTATNP
KPVKLKFEKVYLPCVLQTKKRYVGYMYETLDQKDPVFDAKGIETVRRDSCPAVSKILERS
LKLLFETRDISLIKQYVQRQCMKLLEGKASIQDFIFAKEYRGSSSYKPGACVPALELTRK
MLTYDRRSEPRVGERVPYVIIYGTPGVPLIQLVRRPVEVLQDPTLRLNATYYITKQILPP
LARIFSLIGIDVFNWYHELPRIQKATSSSRSEPEGRKGTISQYFTTLHCPVCDDLTQHGI
CSKCRSQPQHVAVILNQEIRELERKQEQLVKICKNCTGCFDRHIPCVSLNCPVLFKLSRV
NRELSKAPYLRQLLDQF
NT seq 9414 nt   +upstreamnt  +downstreamnt
atgttttcagtgaggatagtgaccgccgactactacatggccagcccgctgcggggcctg
gacacctgcctgtgccccctcacccaggcccctgtcaagaaggtgccggtggtgcgagtc
ttcggagcgaccccggcaggtcagaagacatgtcttcatctgcatggcatctttccttac
ctctatgtgccatacgatggttatggacagcagccagaaagctatctttctcagatggca
ttcagtatcgacagagcacttaatgtggctttaggcaatccatcttccactgctcagcac
gtgttcaaagtgtcattagtatcaggaatgcctttttatggttatcatgagaaggaaaaa
cactttatgaagatctatctttacaatcctgcaatggtgaaaaggatatgtgaacttttg
caaagtggagccataatgaataaattttaccagcctcatgaagcgcatattccctacctc
ctacagctgttcattgactacaatctctatggaatgaatttaataaatctggctgctgtc
aagttccgaaaagcgagaaggaaaagtaatcagttgcatacaactggatcttgcaaggat
cggctaccaggaaattctcttactggtaccttatttcggtgggaagaagatgaaatacca
agctctttaatactggaaggtgttgaacctcagagtacatgtgaattagaagtggatgcc
gtagctgctgatatcttaaatcggctggatattgaagctcaaattggtgggaaccctgga
ctgcaggccatatgggaagatgaaaagcaacggcgaagaaaccgaaatgaaacctctcaa
attaaccaacctgaatcacaagatcgcaggtttgtgccagcaacagaaagtgaaaaaaat
tttcagaagagacttcaggaaattctcaaacagaatgatttctctgtcagaacattatca
ggatcagtggactacagcgatggatctcaggagttctctgctgagttaacactgcactct
gaagttctgtctcctgatactcttcagtgtacaccggctaatatggtagaagtccacaaa
gatacagagttgggcaaaggtcatgctgtgtacaaagtggaggaagctctcattaatgaa
gaagcaattttgaacctcatggaaaatagtcagacttttcagcctttgacccaaagactg
agtgagtcacctgttttcctggacagtagtcctgatgaggctctggtacgtcttcttgct
ggtttggaaaatgatggatatcaggggggaagaaataggatgccatcaccatgtcatttc
tttggaaacactaaaaatccccaaaatagtgatgatgaagaaaatgaaccacagattgaa
aaagaagaaatggagcttagtttggtgatgtctcagagatgggacagcaatattgaagaa
ccttgtgccaaaaagagatcactgtgtagaaatacccgtagaagctcaactgaagaagat
gattcatcctcagaagaagaaatggaatggagtaataacagtttgcttctggccaatctt
tctatacctcagttagatggaactgcagatgaaaatagtgacaatccattgaacaacgaa
aattctaggacccactcttctgtgattgcaacgagcaagctatcagtaaaaccttccatc
tttcacaaagatgctgctacattagaacccccatcttctgctaagattacctttcagtgt
aaacacacaagtgccctttcttcccatgttttgaacaaggaagatttaattgaagacctt
ccacagccaaacaacatagaaaaatgtatagatcattcagttgcttcttttacgaatgaa
agcacttactctatgaaataccctggatctttgagcagttctgtccattcagaaaactct
cataaagaaagtagtaagaaagatatcctcccagtatcttcctgtgaaagtagtattttt
gattacgaagaagatattccatctgttccaagacaagtaccaagtagaaagtatacgaat
attagaaaaattgataaggataccccttttatacacatgaaccgtcatagtagtgaaaat
acattgggcaaaaattctttcaacttttctgacctaagtcatccaaaaaataaattaccc
tctgaaggaaatgaaaaaggaaacagcacagctctgaatagtttattcccttcatcatta
actgaaaattgtgaattgctatcatgctcaggagagaatagaactatggtacattctctt
gatagcattgctgatgaaagtgggctaaataaacttaaaattagatatgaagagtttcag
gaacataaaacagaaaagccaagcctcagccagcaagcagcacattatatgttttttccc
agtgttgttctatctaactgtctgagtagaccacagaaactctctcctgtcacatacaaa
ctacaacccagcagtaaacagtcccggttaaaaattaataaaaagaagcttataggtcat
caagagacttctaccaaaactagtgagactgtatccacaaaagataattgtatacaaaat
aatccttgtaatagtaatcctgagaaggataatgtattggccagtgatttaattaaagtc
acccgcggagcttttgaaaataaaacacccatagacagttttatagactgtcactttgga
gatggaaccttagaaactgagcagtcctttggattgtatggaaataaatatacacttaga
gccaaacgcaaggtaaattatgagactgaagatagtgaatcaagttttgtaacacacaac
tcaaaaattagcctacctcattccatggaaattggtgaaagtttagatggaactctcaaa
tctcgaaaacgaagaaaaatgtctaaaaagctaccccctgtcatcataaagtatattatt
attaacagatttagagggagaaaaaatatgcttgtgaagctaggaaaaatagactctaaa
gaaaaacaagttatattgacagaggaaaaaatggaactgtataagaagcttgcacctttg
aaggatttttggccaaaagttcctgactctcctgcaaccaaatatcccatttatccacta
acaccaaagaaaagtcacagaagaaaatcaaaacataagtctgctaagaaaaaaactggt
aagcaacaaaggacaaatagtgaaaatattaaaagaactttgtcttttaggcgaaaacga
tcacatgctatcctgtctcctccctcaccatcttacaacgctgaaaccgaagactgtgac
ttgaattatagtgatgttatgtctaaactaggttttctttctgaaagaagcacaagtccc
ataaattcttctccccctcgctgctggtctcccacagatccaagagctgaagaaatgatg
gctgctgtagataaagaaacaatgctttttaagggtcctaatgcatgtattaacaagact
gctaattctcgtgtggaaaaaaatagtcgagcaagagcgcaggttaagaaatcgaaaact
aaacttgttaatccctctgtagttactaagaaaaggaacaaacgaaatcagacaaataaa
gtaggagatgatggaaaaaagaaaccgagagcaaaacagaaacaaaaaacaaatgagaaa
ggtatgtcaagaaagcatataacaattaaagatgaaaaaataaaatctcagcctggtgct
gaagttaagtttgtgctgaaacatcagaatgtgtctgagacctcaaatagttctggaggc
tctcaactacttttcaaacagaaagatgtgtcactaatgggctctactatagatcatccc
ctttctgctcccctgcccactggaattcatgcacaacagaatttgtctggctgcttttct
tcttttttagaaagcaagaagcctgtagatttgcaaacattccccagctcacgggatgat
ttgcattcatcagttgtttgtagttctttgggacctggaatctcaaaaattaatgttcag
aggtctcataatcaaagtgctatgtttactctaaaggaatcaaccttgattcaaaaaaat
atatttgatctttccaaccacttgtctcaggtagcacagaatacacagatatcttcgggt
ataacatctccaaagacagaagagaatgcaaatacacaaaaaaactatttgtcatctatc
ggaaagttaaatgaatatcgtaattctttagaatcaaagccagaccaggcatatgcccct
aattttttgcattgcaaagacagtcagcagcagattgtgtgcgggtcagaacagtcaaag
cacaacgaaacttgttctccaggaaatgcagctgcagaggaaagccaaatgcctaataat
tgctttgtaacttccttaagaagtccaatcaaacaaatagcatgggagcaaaaacaaagg
ggctttattttagatatgtcaaattttaaacctgaaagggtaaaacagaggtcgttgtca
gaagcaatttcacaaaccaaagcactttctcagtgtaaaagtcgaaatgtgtcaacacct
tcagcatttggtgaaggccagtctggactggcagttctaaaagaattgttacagaaaaga
cagcagaaagcacaaaatgcaaatattatgcaagacccattatctaataaacatcaacca
aacaaaaatatttctggttccctcgagcaaaacaaaacagttaaaagaacacgatcagta
acatcttcaagaaaacctcgaactccaagaagtacgaaacctaaagaaaaaattcccaaa
cttattaaagtagactctctaaatttacaaaactctgtccagttggataattctctatca
gatgatagtcccatctttttttcagatccaggttttgagagttgttattcacttgaagat
agcttgtctcctgaacataattataattttgatattaatacaataggtcaaactggattt
tgtagtttttattctggaagtcagtttgtcccagctgatcagaatttgcctcagaagttc
ctaagtgatgcagttcaggatcttttcccaggacaagctatagaaaaaaatgagttttta
agtcatgataaccagaagtgtgatgaagacaaacatcatgcctccgactcaacctcgtgg
attagatctagtactttaagtcctgaactatttgagaaatcatccatagataacaatgag
aatcatcgccataaccagtggaaaagtagctttcatcctctaacaactcgctctaattca
ataatggattctttctgtgtccagcaggcagaggattgtctaaatgaaaagtccagattg
aataggagttcagtaagcaaagaagtgtttcttagcctctcacagccaggtacttcagac
tggattcaaggtcataccagaaaagagatgcaacagtctcttgactcagtcaatacctct
tttactacaatactatcgtcccctgatggtgaacttgtggatgcagcctctgaagattta
gaattgtatgtgtccagaaacaatgatatgttaacaccaactcctgatagctccccaagg
tctaccagctctccctcacaatctaaaaacggcagtttcacccctcgaactgctcacatt
ctgaaaccacttatgtccccaccaagtagggaagaaattatggcaactttgttggatcat
gacctctcagaaactatttaccaggaaccattttgcagtaatccttcagatgtaccagaa
aagcccagggagatcggtggacggcttctcatggtagagactcgacttccaaatgatctg
gctgagtttgagggagacttttccttggaaggacttcgtctgtggaaaacagcattctca
gcaatgactcagaatccaagaccagggtcaccccttcgcaatggccaggcagtggtcaat
aaagggtcaagtaatagctctaaaatggctgaagataaaaaaattgtgattatgccttgc
aaatgtgccccaagtcgacaactggttcaagcatggcttcaagccaaagaagaatacgaa
cgttccaagaaactgtctaaaaatgagccaactggagttgtaaaatctgctgagaacttc
agctcttcagttaacccagatgacaaacctgtagtgcctccaaaaatgagtacaactcca
catatactccccactacagcacataccaaggaagatgttgataactctcagtttgcttta
caagccgtaaccacaggatgtagtcaaactgtaagtgaaagtcagacactgccaccagtt
gcttctgcagatgatcctgaaaaaggtgaagatgatgatgatgatgataatgacgactat
tatgttagttatagctcccctgattctccagtaattccaccttggcaacaagcaacatcc
ccagattccaaaatattaaatggagatgagagacccatatcaccagtaaaggaactgcat
tccctgaatattgagaacttcttaaaaccagtaaaagatggtatacagaaaagtccaagc
agtgagccactagagcctctagtgatatctccaattaatgttagggcaagaactggaata
tgtgaatcactttgccttcatagtacaccaattgtccagaggaaatttctggaaaggctt
cctgaagcaagtagcctgagccctttatcaacagaaccaaaaacccagaaattgagtcat
aagaaaggaagtaatactgacacttttagaagaatactcttaacacaagcaaagaatcaa
tttgcagcagtaaataccccaaagaaagaaacttctcagattgatggaccatctttaaac
aatacttatggtttcaaagtcagcgtacaaaacttacaggaggcaaaagctttacatgag
atacaaaatcttaccctaatcagtgtggagttacatgctcgaacgagacgagacttagaa
ccagatcctgaatttgaccccatctgtgctctgttttactgcatctcctctgacacccca
ctaccagatacagacaaaacagaactcacgggtgtaatagtaattgataaagacaagact
gtctccagccaagatatcaggtatcagaccccattgctgattagatctggaattacagga
ctagaagttacctatgcacccgatgagaaggcactttttcaagaaattgcagatataata
aagaggtatgatcctgatattttgctaggatatgaaattcagatgcattcctggggttac
ctcttacaaagggctgctgccttaagtgttgacttaggtcagatgatctctcgggtgcca
gatgacaaaattgagaatagatttgcacctgaaagagatgactatggatcagaaacaatg
agtgaaataaatattgttggccgaattacactaaatctttggagaatcatgagaaatgag
gtggctttaactaactacacctttgaaaatgtgagctttcatgttcttcatcagcgtttt
cccctctttacctttcgagtcttatcagattggtttgataacaagacagatctgtacaga
tggaaaatggttgatcactacattagccgtgtccgtggaaatctccaaatgttagaacag
ttggacctgattgggaaaaccagtgaaatggctagactctttggcatccagtttttacat
gtactgacaaggggttcacagtaccgtgtggaatcaatgatgttgcgtattgctaaacca
atgaactatattcctgtgacacctagtgtacagcaaagatcccaaatgagagccccacag
tgtgttcccctaattatggagcctgaatctcgcttctatagcaactctgttctcgttttg
gatttccagtcactatatccttcgattgtgattgcgtacaactactgtttttccacctgc
cttggccatgtggagaacctgggaaagtatgatgagttcaaatttggctgtacctctcta
agagtacctccagatttactttaccaaattaggcatgatatcacagtgtcccccaatgga
atagcttttgtcaagccttcagtaagaaagggtgtgctaccaagaatgcttgaagaaatt
ttgaagactagactcatggtgaaacagtcaatgaaggcttacaagcaagacagagccctt
tcacgaatgctcgatgcacgtcaactaggacttaagcttatagcaaatgtcacatttggc
tatacagctgcgaatttttctgggagaatgccatgcattgaggttggtgatagtattgtt
cacaaagccagagagaccttggagcgagctattaaactggtgaatgataccaagaaatgg
ggcgctagggttgtatatggagatactgacagtatgtttgtgctactgaaaggagccact
aaggagcagtcttttaagattggtcaggaaattgctgaagctgtaactgctaccaatcct
aaaccagtgaaattgaagtttgaaaaggtatatttgccctgtgtcttacaaacaaaaaag
aggtatgtgggttacatgtatgaaacactggatcaaaaggacccggtatttgatgcaaaa
ggaatagaaacagtcagaagagattcctgccctgctgtttctaagatacttgagcgttct
ctaaagctgctatttgaaacaagagatataagtttaattaaacagtatgttcagcgacaa
tgtatgaaacttctggaaggaaaagccagcatccaagattttatctttgccaaggaatac
agaggaagttcctcttataaacctggagcttgtgtgccagcccttgaacttacaaggaaa
atgcttacttacgatcggcgctctgagcctcgagttggagagcgagtgccatacgtcatc
atttatgggacccccggagtaccacttatccagctagtgaggcgcccagtggaagtgctg
caggacccgactctgagactgaatgccacttactacatcaccaagcaaatcctgccaccc
ctggcaagaatcttctcacttattggtattgatgtcttcaactggtatcatgaattacca
aggatccagaaagccaccagctcctctcgaagtgaacctgaagggcgaaaaggcactatt
tcacaatatttcactactttacactgtcccgtgtgtgatgacctaacccagcatggcatc
tgtagtaaatgtcggagccaacctcagcatgttgcagtcatccttaaccaagaaattcga
gagttggaacgtaaacaggaacaacttgtaaagatatgcaagaactgtacagggtgcttt
gaccgacatatcccgtgtgtttctctcaactgcccagtacttttcaaactctcccgagta
aatagagaattatccaaggcaccatatctccggcaattactagaccagttttaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (45)   
   KEGG ORTHOLOGY (1)   
   RefGene (39)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (16)   
   UniProt (1)   
   RefSeq(pep) (15)   
DNA sequence (25)   
   RefSeq(nuc) (25)   
Protein domain (4)   
   Pfam (4)   
All databases (97)   

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