KEGG   Canis lupus familiaris (dog): 482197
Entry
482197            CDS       T01007                                 
Symbol
MTHFD2L
Name
(RefSeq) probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X2
  KO
K13403  methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.15 3.5.4.9]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa00670  One carbon pool by folate
cfa01100  Metabolic pathways
cfa01240  Biosynthesis of cofactors
Module
cfa_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    482197 (MTHFD2L)
Enzymes [BR:cfa01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.15  methylenetetrahydrofolate dehydrogenase (NAD+)
     482197 (MTHFD2L)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     482197 (MTHFD2L)
SSDB
Motif
Pfam: THF_DHG_CYH_C THF_DHG_CYH AlaDh_PNT_C Sacchrp_dh_NADP
Other DBs
NCBI-GeneID: 482197
NCBI-ProteinID: XP_022282803
Ensembl: ENSCAFG00000028758
VGNC: 51777
Position
13:62354053..62490793
AA seq 263 aa
MAKQIQKEIQRGVESWISLGNRRPHLSIILVGDNPASHTYVRKKIRAASAVGICSEIILK
PKDVSQEELLDITDQLNMDPRVSGILVQLPLPDHVDERTVCNGIAPEKDVDGFHIINIGR
LCLDQHSLIPATASAVWEIIKRTGIETFGKNVVVAGRSKNVGMPIAMLLHTDGEHERPGG
DATVTIAHRYTPKEQLKIHTQLADIIIVAAGIPKLITSDMVKEGAAVIDVGINYVHDPVT
GKTKLVGDVDFEVEWPCTERWCD
NT seq 792 nt   +upstreamnt  +downstreamnt
atggccaaacaaattcagaaagaaatacagagaggtgtggaatcatggatttcccttggg
aacagaagacctcacctcagtatcatcttagtgggcgataacccagcaagccatacgtac
gtcaggaagaagatcagagccgcctctgctgtaggtatctgtagtgagatcattctaaaa
cctaaggatgtttctcaggaagaacttttggacataactgatcaattgaatatggaccca
agagtcagtggtatattagttcagttgccactgccagaccatgtggatgagcgaacagtg
tgcaatggaattgcccctgaaaaagatgtagatggatttcatattatcaatattggaaga
ctgtgccttgatcagcattctctcatacccgccactgccagtgcagtttgggaaataatc
aagagaacaggaattgaaacatttgggaaaaatgtggttgtagctggaagatccaagaat
gtagggatgcccattgccatgcttttacacactgatggagaacacgaacggccaggaggt
gatgcaacggtgacaatagctcacagatacactcccaaagaacaactgaagatccatact
cagctggcagatattatcatagtagctgccggtattccaaagttgattacatctgatatg
gttaaagaaggtgctgctgtaattgatgtgggtatcaactatgtccatgacccagtgaca
ggaaagacaaaactggttggagatgtggactttgaagtggaatggccttgtaccgagagg
tggtgtgactga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (4)   
   KEGG ENZYME (2)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (33)   
   KEGG ORTHOLOGY (1)   
   RefGene (27)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (35)   
   RefSeq(pep) (35)   
DNA sequence (45)   
   RefSeq(nuc) (45)   
Protein domain (4)   
   Pfam (4)   
All databases (135)   

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