KEGG   Canis lupus familiaris (dog): 484420
Entry
484420            CDS       T01007                                 
Symbol
SLC8A2
Name
(RefSeq) sodium/calcium exchanger 2 isoform X1
  KO
K05849  solute carrier family 8 (sodium/calcium exchanger)
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa04020  Calcium signaling pathway
cfa04022  cGMP-PKG signaling pathway
cfa04260  Cardiac muscle contraction
cfa04261  Adrenergic signaling in cardiomyocytes
cfa04371  Apelin signaling pathway
cfa04740  Olfactory transduction
cfa04961  Endocrine and other factor-regulated calcium reabsorption
cfa04974  Protein digestion and absorption
cfa04978  Mineral absorption
cfa05410  Hypertrophic cardiomyopathy
cfa05412  Arrhythmogenic right ventricular cardiomyopathy
cfa05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    484420 (SLC8A2)
   04020 Calcium signaling pathway
    484420 (SLC8A2)
   04022 cGMP-PKG signaling pathway
    484420 (SLC8A2)
 09150 Organismal Systems
  09153 Circulatory system
   04260 Cardiac muscle contraction
    484420 (SLC8A2)
   04261 Adrenergic signaling in cardiomyocytes
    484420 (SLC8A2)
  09154 Digestive system
   04974 Protein digestion and absorption
    484420 (SLC8A2)
   04978 Mineral absorption
    484420 (SLC8A2)
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    484420 (SLC8A2)
  09157 Sensory system
   04740 Olfactory transduction
    484420 (SLC8A2)
 09160 Human Diseases
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    484420 (SLC8A2)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    484420 (SLC8A2)
   05414 Dilated cardiomyopathy
    484420 (SLC8A2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:cfa02000]
    484420 (SLC8A2)
   00536 Glycosaminoglycan binding proteins [BR:cfa00536]
    484420 (SLC8A2)
Transporters [BR:cfa02000]
 Solute carrier family (SLC)
  SLC8: Na+/Ca2+ exchanger
   484420 (SLC8A2)
Glycosaminoglycan binding proteins [BR:cfa00536]
 Heparan sulfate / Heparin
  Others
   484420 (SLC8A2)
SSDB
Motif
Pfam: Calx-beta Na_Ca_ex_C Na_Ca_ex
Other DBs
NCBI-GeneID: 484420
NCBI-ProteinID: XP_005616441
Ensembl: ENSCAFG00000004140
VGNC: 46481
Position
1:108026547..108056879
AA seq 921 aa
MAPLALVGFALLLGTPLCSGAATPTPSLPPPPTNDSDTSTGGCQGSNRCQPGVLLPVWEP
DDPSLGDKAARAVVYFVAMVYMFLGVSIIADRFMASIEVITSKEKEITITKANGETSVGT
VRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFQAGELGPGTIVGSAAFNMFVVIAVC
IYVIPAGESRKIKHLRVFFVTASWSIFAYVWLYLILAVFSPGVVQVWEALLTLVFFPVCV
VFAWMADKRLLFYKYVYKRYRTDPRSGIIIGAEGDPPKSIELDGTFVGAEVPGELGGLGP
GPAEARELDASRREVIQILKDLKQKHPDKDLEQLVGIANYYALLHQQKSRAFYRIQATRL
MTGAGNVLRRHAVDASRRASPAEGPGEDEDDGASRIYFEPSLYHCLENCGSVLLSVTCQG
GEGNSTFYVDYRTEDGSAKAGSDYEYSEGTLVFKPGETQKELRIGIIDDDIFEEDEHFFV
RLLNLRVGDAQGMFEPDGGGRPKGRLVAPLLATVTILDDDHAGIFSFQDRLLHVSECMGT
VDVRVVRSSGARGTVRLPYRTVDGTARGGGVHYEDACGELEFGDDETMKTLQVKIVDDEE
YEKKDNFFIELGQPQWLKRGISALLLNQGDGDRKLTAEEEEARRIAEMGKPVLGENCRLE
VIIEESYDFKNTVDKLIKKTNLALVIGTHSWREQFLEAVTVSAGDEEEEEDGSREERLPS
CFDYVMHFLTVFWKVLFACVPPTEYCHGWACFGVCILVIGLLTALIGDLASHFGCTVGLK
DSVNAVVFVALGTSIPDTFASKVAALQDQCADASIGNVTGSNAVNVFLGLGVAWSVAAVY
WAVQGRPFEVRTGTLAFSVTLFTVFAFVGIAVLLYRRRPHIGGELGGPRGPKLATTALFL
GLWFLYILFASLEAYCHIRGF
NT seq 2766 nt   +upstreamnt  +downstreamnt
atggctcccttggccttagtggggtttgcactcctcctggggacgcccctatgctcaggg
gcggccacccccactccctccctgccacctcccccaaccaatgacagtgataccagcaca
gggggctgccagggctccaaccgctgccagccgggggtcctgctgcctgtgtgggagccc
gatgacccgtcgctgggtgacaaagcagcgagagcagtggtctacttcgtggccatggtt
tacatgttcctgggcgtgtccatcatcgctgaccgcttcatggcatccatcgaggtcatc
acatcaaaggagaaggagattaccatcaccaaagccaatggtgagaccagcgtgggcacc
gtccgcatctggaacgagacagtgtccaacctcacactcatggccctggggtcctcagcc
cctgagatcctgctgtctgtcatcgaggtctgtggccacaacttccaggcgggcgagctg
ggccctggcaccatcgtgggcagtgctgccttcaacatgttcgttgtcattgccgtgtgc
atctatgtcatcccagccggcgagagccgcaagatcaagcacctgagagtcttctttgtc
actgcctcttggagtatcttcgcctacgtctggctttatctcatccttgccgtcttttcc
ccgggtgtggtccaggtgtgggaggcgctgctgaccctcgtcttcttcccggtgtgcgtg
gtgttcgcctggatggccgataagcggctgctcttctacaagtacgtgtacaagcgctac
cgcaccgacccgcgcagcggcatcatcatcggcgccgagggcgacccccccaagagcatc
gagctggacggcacgttcgtgggcgccgaggtgccgggcgagctgggcggcctgggcccg
ggccccgccgaggcccgcgagctggacgccagccgccgcgaggtcatccagatcctcaag
gacctcaagcagaagcacccggacaaggacctggagcagctggtgggcatcgccaactac
tacgcgctgctgcaccagcagaagagccgcgccttctaccgcatccaggccacgcggctc
atgacgggcgcgggcaacgtgctgcggcgacacgcggtggacgcgtcgcgcagggcgtcc
ccggccgagggccccggcgaggacgaggacgacggcgccagccgcatctacttcgagccc
agcctctaccactgcttggagaactgcggctcggtgctgctgtccgtcacctgccagggc
ggggagggcaacagcacgttctacgtggactaccgcaccgaggacggctccgccaaggcc
ggctccgactacgagtacagcgagggcacgctggtgttcaagccgggcgagacgcagaag
gagctgcgcattggcatcatcgacgacgacatctttgaggaggacgaacacttcttcgtg
cggctactgaacctgcgcgtcggcgacgcgcagggcatgttcgagcccgacggcggcggg
cgacccaagggacggctggtggcgccgctgctggccactgtcaccatcctggacgacgac
cacgcgggcatcttctccttccaggaccgcctgctgcacgtgagcgagtgcatgggcacc
gtggacgtgcgcgtcgtgcgcagctcgggcgcccggggcaccgtgcgccttccataccgc
acggtggacggcacggcgcgcggcggcggcgtgcactacgaggacgcgtgcggcgagctc
gagttcggcgacgacgagaccatgaaaactcttcaggtaaagatagttgatgacgaggaa
tatgagaaaaaggataatttcttcatcgaactgggccagccgcagtggctgaagcgaggg
atttcagctctgctgctcaatcaaggggatggggacaggaagttgacagctgaggaggag
gaggctcggaggatagcagagatgggcaagccagttcttggggaaaactgccgactggaa
gtcatcatcgaggagtcatatgattttaagaacacagtggataaactcatcaagaaaacc
aacttggctttggtgattgggacccattcctggagggaacagtttttagaggcagttacg
gtgagcgcaggggacgaggaggaggaggaggacgggtcccgggaggaacggctgccttcc
tgctttgactacgtcatgcacttcctgacggtgttctggaaggtgctttttgcctgcgtg
ccccccaccgagtactgccacggctgggcctgcttcggggtctgcatcctggtcatcggc
ctcctcaccgcactcatcggggacctggcctcccactttggctgcaccgttggcctcaag
gactctgtcaacgctgtagtcttcgtggccctgggcacctccatccctgacacgttcgcc
agcaaggtggcggcgctgcaggaccagtgcgcggacgcgtccatcggcaacgtgacgggc
tccaacgccgtgaacgtgttcctgggcctcggcgtggcctggtcggtggccgccgtgtac
tgggcggtgcagggccgcccgttcgaggtgcgcaccggcacgctggccttctccgtcacg
ctcttcaccgtcttcgccttcgtgggcatcgccgtgctgctgtaccggcgccggccgcac
atcgggggcgagctgggcggcccgcgcggccccaagctcgccaccaccgcgctcttcctg
ggcctctggttcctctacatcctcttcgccagcctcgaggcctactgccacatccggggc
ttctag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (12)   
   KEGG PATHWAY (12)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   RefGene (16)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (30)   
   RefSeq(pep) (30)   
DNA sequence (30)   
   RefSeq(nuc) (30)   
Protein domain (3)   
   Pfam (3)   
All databases (101)   

Download RDF
DBGET integrated database retrieval system