KEGG   Canis familiaris (dog): 487870Help
Entry
487870            CDS       T01007                                 

Gene name
EIF4E
Definition
(RefSeq) eukaryotic translation initiation factor 4E isoform X1
  KO
K03259  translation initiation factor 4E
Organism
cfa  Canis familiaris (dog)
Pathway
cfa01521  EGFR tyrosine kinase inhibitor resistance
cfa03013  RNA transport
cfa04066  HIF-1 signaling pathway
cfa04150  mTOR signaling pathway
cfa04151  PI3K-Akt signaling pathway
cfa04211  Longevity regulating pathway
cfa04910  Insulin signaling pathway
Module
cfa_M00428  eIF4F complex
Brite
KEGG Orthology (KO) [BR:cfa00001]
 Genetic Information Processing
  Translation
   03013 RNA transport
    487870 (EIF4E)
 Environmental Information Processing
  Signal transduction
   04066 HIF-1 signaling pathway
    487870 (EIF4E)
   04151 PI3K-Akt signaling pathway
    487870 (EIF4E)
   04150 mTOR signaling pathway
    487870 (EIF4E)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    487870 (EIF4E)
  Aging
   04211 Longevity regulating pathway - mammal
    487870 (EIF4E)
 Human Diseases
  Drug resistance
   01521 EGFR tyrosine kinase inhibitor resistance
    487870 (EIF4E)
Messenger RNA biogenesis [BR:cfa03019]
 Eukaryotic Type
  mRNA surveillance and transport factors
   Transport factors
    eIF4F and regulatory proteins
     487870 (EIF4E)
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     487870 (EIF4E)
Translation factors [BR:cfa03012]
 Eukaryotic Type
  Initiation factors
   eIF-4
    487870 (EIF4E)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: IF4E
Motif
Other DBs
NCBI-GeneID: 487870
NCBI-ProteinID: XP_005639274
Ensembl: ENSCAFG00000010307
VGNC: 40283
Position
32
AA seq 230 aa AA seqDB search
MLLRRARELPGLAAGEARKETTPTPNPPPTEEEKTESNQEVANPEHYIKHPLQNRWALWF
FKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKN
KRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWT
TECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV
NT seq 693 nt NT seq  +upstreamnt  +downstreamnt
atgttactccggcgcgcccgagagttgccggggttggcggcaggggaggcgagaaaggaa
accacccctactcctaatcccccgcctacagaagaagagaaaacagaatctaatcaggag
gttgctaacccagaacactatattaaacatcctttacagaacagatgggcactctggttt
tttaaaaatgataaaagcaaaacttggcaagcaaaccttcggctgatctctaagtttgat
actgttgaagacttttgggctctgtacaaccacatccagttgtctagtaatttaatgcct
ggctgtgactactcactttttaaggatggtattgagcctatgtgggaagatgagaaaaac
aaacgaggaggacgatggctaattacattgaacaagcagcagagacgtagtgacctggat
cgcttttggctagagacactgctgtgccttattggagaatcttttgatgactacagtgat
gatgtatgtggagctgttgttaatgttagagctaaaggtgataagatagcaatatggact
actgaatgtgaaaacagagaggctgttacacatatagggagggtatacaaggaaaggtta
ggacttcctccaaagatagtgattggttatcagtcccatgcagacacagctacaaagagc
ggctccactactaaaaataggtttgttgtttaa

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