KEGG   Canis lupus familiaris (dog): 489373
Entry
489373            CDS       T01007                                 
Symbol
HMBS
Name
(RefSeq) porphobilinogen deaminase isoform X2
  KO
K01749  hydroxymethylbilane synthase [EC:2.5.1.61]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa00860  Porphyrin metabolism
cfa01100  Metabolic pathways
cfa01240  Biosynthesis of cofactors
Module
cfa_M00868  Heme biosynthesis, animals and fungi, glycine => heme
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    489373 (HMBS)
Enzymes [BR:cfa01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.61  hydroxymethylbilane synthase
     489373 (HMBS)
SSDB
Motif
Pfam: Porphobil_deam Porphobil_deamC MGS
Other DBs
NCBI-GeneID: 489373
NCBI-ProteinID: XP_005619738
Ensembl: ENSCAFG00000012342
VGNC: 41704
UniProt: A0A8C0TCQ7
Position
5:complement(14820660..14828175)
AA seq 344 aa
MRVIRVGTRKSQLARIQTDSVVAMLKALYPGLQFEIVAMSTTGDKILDTALSKIGEKSLF
TKELEHALEKNEVDLVVHSLKDLPTVLPPGFTIGAICKRENPYDAVVFHPKFVGKTLETL
PEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDELQEFSAIILAAAGLQRMG
WQHRVGQILHPEECMYAVGQGALGVEVRAKDQDMLDLVGVLHDPETLLRCIAERAFLRHL
EGGCSVPVAVHTAMKDGQLYLTGGVWSLDGSDSMQETMQATIHITAQHEDGPEDDPQLVG
ITARNIPREAQLAAENLGISLASLLLNKGAKNILDVARQLNDAH
NT seq 1035 nt   +upstreamnt  +downstreamnt
atgagagtgattcgtgtgggtacccgaaagagccagctggctcgcatacagacagacagt
gtggtggcaatgctgaaagccttgtacccaggcctacagtttgaaattgttgctatgtcg
accacgggggacaagattcttgacactgcactctctaagattggagagaagagcctgttt
accaaggagctggaacacgcgctggagaagaacgaagtcgacctggttgttcactctctg
aaggacctgcccacagtgcttcctcctggcttcaccatcggagccatctgcaagcgggag
aacccctatgatgctgttgtctttcacccaaaatttgttgggaaaactctagaaaccttg
ccagagaagagcgtggtgggaaccagctccctgcggagagcagctcagctgcagagaaag
ttcccgcacctagagttcaggagcattcggggaaatctcaacacccggctccggaagctg
gatgagctgcaggagttcagtgccatcatcctggctgcggctggtctgcagcgcatgggc
tggcagcaccgagtggggcagatcctgcacccagaggaatgcatgtatgctgtgggtcag
ggggccctgggcgtggaagtccgagccaaggaccaggacatgctggacctggtgggcgtg
ttgcatgatccggagactctgcttcgctgcattgctgagcgagccttccttaggcacctg
gagggaggctgcagtgtgccagtggcagtgcatacagctatgaaggatgggcaactgtac
ctgactggaggagtctggagtctagacggctcagatagcatgcaagagaccatgcaggcc
accatccacatcacagcccagcatgaagatggccccgaggatgatccgcagctggtgggg
atcactgcccggaacattccacgagaagcccagctggctgctgagaacctgggcatcagc
ctggccagtttgctgctgaacaaaggagccaagaacatactggatgttgcacggcagctt
aatgatgcccactaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (3)   
   KEGG MODULE (4)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (26)   
   UniProt (1)   
   RefSeq(pep) (25)   
DNA sequence (25)   
   RefSeq(nuc) (25)   
Protein domain (3)   
   Pfam (3)   
All databases (77)   

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