KEGG   Canis lupus familiaris (dog): 490305
Entry
490305            CDS       T01007                                 
Symbol
CACNA1E
Name
(RefSeq) voltage-dependent R-type calcium channel subunit alpha-1E isoform X41
  KO
K04852  voltage-dependent calcium channel R type alpha-1E
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa04010  MAPK signaling pathway
cfa04020  Calcium signaling pathway
cfa04930  Type II diabetes mellitus
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    490305 (CACNA1E)
   04020 Calcium signaling pathway
    490305 (CACNA1E)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    490305 (CACNA1E)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:cfa04040]
    490305 (CACNA1E)
Ion channels [BR:cfa04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   490305 (CACNA1E)
SSDB
Motif
Pfam: Ion_trans Ca_chan_IQ GPHH PKD_channel
Other DBs
NCBI-GeneID: 490305
NCBI-ProteinID: XP_022276636
Ensembl: ENSCAFG00000013004
VGNC: 38635
Position
7:14468762..14855678
AA seq 2358 aa
MKRRRGGLIEQRDIIKAHEAHKMQSTPQARRKEWEMARFGEAVVGRPGSGDGDSDQSRNR
QGTPVPASGPAAAYKQSKAQRARTMALYNPIPVRQNCFTVNRSLFIFGEDNIVRKYAKKL
IDWPPFEYMILATIIANCIVLALEQHLPEDDKTPMSRRLEKTEPYFIGIFCFEAGIKIVA
LGFIFHKGSYLRNGWNVMDFIVVLSGILATAGTHFNTHVDLRTLRAVRVLRPLKLVSGIP
SLQIVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYSGKLHRACFTNNSGILEGFDPP
HPCGVQGCPAGYECRDWIGPNDGITQFDNILFAVLTVFQCITMEGWTTVLYNTNDALGAT
WNWLYFIPLIIIGSFFVLNLVLGVLSGEFAKERERVENRRAFMKLRRQQQIERELNGYRA
WIDKAEEVMLAEENKNAGTSALEVLRRATIKRSRTEAMTRDSSDEHCVDISSVGTPLARA
SIKSAKVDGASYFRHKERLLRISIRHMVKSQVFYWIVLSLVALNTACVAIVHHNQPQWLT
HLLYYAEFLFLGLFLLEMSLKMYGMGPRLYFHSSFNCFDFGVTVGSIFEVVWAIFRPGTS
FGISVLRALRLLRIFKITKYWASLRNLVVSLMSSMKSIISLLFLLFLFIVVFALLGMQLF
GGRFNFNDGTPSANFDTFPAAIMTVFQILTGEDWNEVMYNGIRSQGGVSSGMWSAIYFIV
LTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEEEAFNQKHALQKAKEVSPMSAPNMPS
IERDRRRRHHMSMWEPRSSHLRERRRRHHMSVWEQRTSQLRRHMQMSSQEALNKEEAPPM
NPLNPLNPLSPLNPLNAHPSLYRRPRPIEGLGLGLEKCEEERIISRGGSLKGDGGDLSSA
LDNQRSPLSLGKREPPWLARPCHGNCDPTQQEAGGGETVVTFEDRARHRQSQRRSRHRRV
RTEGKELSSTSRSRSVSQERSLDEGVLTDGEKEREPRGGHAGKEPTIQEEDRGQDLRRTN
SLMVPRGSGLAGALDEANTPLVLPHHDLEVGKDTVLTEQEPEGSSEQALLGDVQLDIGRV
ISQSEPDLSCVTANTDKATTDSTSVTVAIPDVGPLMDSTVIHISNKTDGEASPLKEAEIK
EEEEEMEKKQQKKEKRETGKAMVPHSSMFIFSTTNPIRRACHYIVNLRYFEMCILLVIAA
SSIALAAEDPVLTNSERNKVLRYFDYVFTGVFTFEMVIKMIDQGLILQDGSYFRDLWNIL
DFVVVVGALVAFALANALGTNKGRDIKTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVVTS
LKNVFNILIVYKLFMFIFAVIAVQLFKGKFFYCTDSSKDTEKECIGNYVDHEKNKMEVKG
REWKRHEFHYDNIIWALLTLFTVSTGEGWPQVLQHSVDVTEEDRGPSRSNRMEMSIFYVV
YFVVFPFFFVNIFVALIIITFQEQGDKMMEECSLEKNERACIDFAISAKPLTRYMPQNRH
TFQYRVWHFVVSPSFEYTIMAMIALNTVVLMMKYYSAPCTYELALKYLNIAFTMVFSLEC
VLKIIAFGFLNYFRDTWNIFDFITVIGSITEIILTDSKLVNTSGFNMSFLKLFRAARLIK
LLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIKLDEESHINRHNN
FRSFFGSLMLLFRSATGEAWQEIMLSCLGEKGCEPDTTAPSGQNENERCGTDLAYVYFVS
FIFFCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFVRVWAEYDRAACGRIHYTEMY
EMLTLMSPPLGLGKRCPSKVAYKRLVLMNMPVAEDMTVHFTSTLMALIRTALDIKIAKGG
ADRQQLDSELQKETLAIWPHLSQKMLDLLVPMPKASDLTVGKIYAAMMIMDYYKQSKVKK
QRQQLEEQKNAPMFQRMEPSSLPQEIIANAKALPYLQQDPVSGLSGRSGYPSMSPLSPQE
IFQLACMDPADDGQFQEHQSLEPEVSELKSVQSSNHGIYLPSDTQEHTGSGRASSMPRLT
VDPQVVTDTSSMRRSFSTIRDKRSNSSWLEEFSMERSSENTYKSRRRSYHSSLRLSAHRL
NSDSGHKSDTHRSGGRERGRSKERKHLLSPDVSRCNSEERGTQADWESPERQQSRSPSEA
RSQTPNRQGTGSLSESSIPSISDTSTPRRSRRQLPPVPPKPRPLLSYSSLIRHSGSISPP
ADGSERGSPLTPQALESTEAGLAEPSGPRHGHGQGHGQGHGQQSQHCSPQRYISEPYLAL
HEDSHASDCGEEETLTFEAAVATSLGRSNTIGSAPPLRHSWQMPNGHYRRRRRGGPGPGV
MCGAVSDLLSDTEEDDKC
NT seq 7077 nt   +upstreamnt  +downstreamnt
atgaagcggcggcgcgggggcctcatcgagcagcgcgacatcatcaaggcccacgaggcg
cacaagatgcagagcaccccgcaggcgcggcgcaaggagtgggagatggctcgcttcggg
gaggcggtggtcggcaggccggggtcgggcgatggagactcggaccagagcaggaaccgg
caaggaaccccggtgccggcctcggggccggcggccgcctacaagcagtcgaaagcgcag
agggcgcggactatggctttgtacaaccccattcccgtccggcagaactgtttcaccgtc
aacagatccctgttcatcttcggagaagataacattgtcaggaaatacgccaagaagctc
atcgactggccgccgtttgagtacatgattttggcaaccatcattgccaactgcattgtc
ttggccctggaacagcatcttcctgaggatgacaagaccccgatgtcccgcagactggag
aagacagagccgtatttcattgggatcttttgctttgaagccggtatcaaaattgtggcc
ctggggttcatctttcataagggctcgtacctccgcaatggctggaatgtcatggacttc
atcgtggtcctcagtggcatcctggccactgcggggactcacttcaacacacacgtggac
ctgaggaccctccgggctgtgcgtgtcctgagacccctgaagctcgtgtcagggattcct
agcctgcagatcgtgttgaagtctatcatgaaggccatggtgcctcttctgcaaattggt
ctcctgctcttctttgccatcttgatgtttgctatcattggcttagagttctacagtggg
aagttgcaccgagcatgtttcacgaacaattcaggtattctggaaggatttgacccccct
cacccatgtggtgtgcagggctgcccagctggctacgaatgccgggactggattggcccc
aatgatgggatcacccagtttgataacatcctttttgctgtgctgactgtcttccaatgc
atcaccatggaaggatggaccaccgtgctgtacaataccaatgatgccttaggagccacc
tggaactggctgtacttcatccccctcatcatcattggatccttctttgttctcaaccta
gttctgggagtgctttccggggagtttgccaaagagagagagagagtggagaaccggaga
gctttcatgaaactgcggcggcagcagcagattgagcgggagctgaacgggtaccgcgcc
tggatagacaaagcagaggaagtcatgcttgctgaagaaaataaaaatgctgggacgtca
gccttagaagtgcttcgaagggcaaccatcaaaaggagccggacagaggccatgactcga
gactccagtgatgaacactgtgtcgatatctcctctgtgggcacacctctcgcccgagcc
agcatcaaaagtgcaaaggtggatggggcctcctatttccggcacaaagaaaggcttctg
cgcatctctatccgccacatggtgaaatcccaggtgttttactggattgtgttgagcctt
gtggctctcaacactgcctgtgtggccatcgtccatcataaccagccccagtggctcacc
catctcctctactatgcagaatttttgtttctgggactgttcctcttggagatgtccctg
aagatgtatggcatgggacctcgactttattttcactcttcattcaactgttttgatttt
ggggtcacagtgggcagcatctttgaagtggtctgggcaatcttcagacctggcacatct
tttggaatcagtgtcttacgggctctccggcttctaagaatatttaaaataaccaagtat
tgggcatctctgcgaaatttggtggtctccttgatgagctctatgaagtctatcatcagt
ttgctcttcctcctcttcctcttcatcgttgtctttgctctcctaggaatgcagctgttt
ggaggcaggtttaactttaatgatgggactccttcagcaaactttgataccttccctgca
gccatcatgactgtattccagatcctaacaggtgaggactggaatgaggtgatgtacaat
gggatccgttcccagggtggagttagctcaggcatgtggtcagctatctatttcattgtg
ctcaccttgtttggaaactacacactgctgaatgtgttcttggccattgctgtggacaat
ctggccaatgcccaagagctgaccaaggatgaacaagaagaagaggaggcttttaaccag
aaacatgcattgcagaaggccaaggaggtcagcccgatgtctgcacccaacatgccttct
atcgaaagagacagaaggagaagacaccacatgtcgatgtgggagccacgcagcagccac
ctgagggagcggaggcgccggcaccacatgtcggtgtgggagcagcgcaccagccagctg
agaaggcacatgcagatgtccagccaggaggccctcaataaagaggaggccccaccgatg
aaccccctcaaccccctcaacccgctgagccccctcaacccgctcaacgcccaccccagc
ctctaccggagacctaggcctattgagggcctgggcctgggcctggagaagtgtgaggag
gagcgcatcatcagccgcggggggtccctcaagggggacggaggggacctgtcgagtgcc
ctggacaaccagaggagccctttgtccctgggcaaacgggagccaccatggctggccagg
ccctgtcatgggaactgtgatccgacccagcaggaggctgggggaggggagaccgtggtg
accttcgaggaccgggccaggcacaggcagagccagcggcgcagccggcaccgtcgtgtc
aggacggaaggcaaggagctctcctccacctcccggagcaggtctgtcagccaggagcgg
agtctggatgagggggtgctcaccgacggggagaaggagcgagagcccaggggcggccat
gcaggcaaagaacccaccatccaagaagaagacagaggccaagacttaaggaggacgaac
agtctgatggtgcccagaggctctgggctggcaggagcccttgatgaggccaacacaccc
ctagtcctgccccaccacgatctggaagtggggaaggacacggtgctgacggagcaggag
ccggagggcagcagcgagcaggccctgctgggggatgtgcagttggacattggcagggtc
atcagccagagtgagcctgacctctcctgcgtcacagccaacacagacaaggccaccacc
gacagcaccagcgtcaccgtcgccatccctgatgtgggccccttgatggactcaactgtg
attcacattagcaacaaaactgatggagaagccagtcccttgaaggaggctgagatcaaa
gaggaggaggaggaaatggagaagaagcagcagaagaaggagaagcgtgagacgggcaaa
gccatggtgccccacagctctatgttcatcttcagcaccaccaacccgattcgcagggcc
tgccactacatcgtgaacctgcgctactttgagatgtgcattctcctggtgatcgccgcc
agcagcattgccctggcagcagaggaccccgtcctgaccaactcggagcgcaacaaagtc
ctgaggtattttgactatgttttcactggcgtgttcacctttgagatggttataaagatg
atagaccagggcttgatcctacaggatgggtcctacttccgagacctgtggaacatcctg
gactttgtggtggtggttggtgcattggtggcctttgctttggcgaacgctttgggaaca
aacaaggggcgagacatcaagaccatcaaatccctgagggtgctccgagttctgaggcca
ctgaagaccatcaagcgcttgcccaaactcaaggctgtctttgactgtgtggtgacctcc
ttgaagaatgtcttcaacatactcatcgtctataagctcttcatgttcatctttgctgtc
attgcggttcagctcttcaagggaaaattcttttattgcacagacagttccaaggacaca
gagaaggagtgcataggcaactacgtagatcatgaaaaaaacaagatggaggtgaaaggc
cgggaatggaagcgccatgaattccactacgacaacattatctgggccctgctgaccctc
ttcaccgtctccacgggggaaggatggcctcaagtcttacagcattctgtcgatgtgaca
gaggaagaccgaggaccaagccgcagcaaccgcatggagatgtccatcttctatgtggtc
tactttgtggtcttccctttcttctttgtcaatatctttgtggctctgatcatcatcacc
ttccaggaacaaggggacaagatgatggaggaatgcagcctggagaagaacgagagggcg
tgcattgacttcgccatcagtgccaaacctctcacccgctacatgccacagaacaggcac
accttccagtaccgcgtctggcacttcgtggtgtctccgtcctttgagtacaccatcatg
gccatgatcgccctgaacaccgtcgtgctgatgatgaagtactactctgctccctgtacc
tatgaactggccctgaagtacctgaatattgccttcaccatggtgttttccctggaatgt
gtcctaaagatcatcgcttttggcttcttgaactactttcgagacacctggaacatcttt
gacttcatcactgtgattggcagtatcacagaaatcatactgacagacagcaagctggta
aacaccagtggtttcaacatgagctttctgaagctcttccgtgccgcccgcctcatcaag
cttctgcggcagggctacaccatccgtattttactctggaccttcgtgcagtcctttaag
gccctcccctacgtctgccttttgattgccatgcttttcttcatctatgccatcattggg
atgcaggtatttggaaacataaaattagatgaggagagtcacatcaaccggcacaacaac
ttccggagtttctttgggtccctcatgttactcttcaggagtgccacgggagaggcctgg
caggagataatgctgtcgtgcctcggggagaaaggctgcgagcccgacaccactgcgcca
tcggggcagaacgagaatgagcgctgtggcaccgatctggcctatgtttactttgtctcc
ttcatcttcttctgctctttcttgatgctcaacttgtttgtggccgtcatcatggacaac
ttcgagtacctgactcgggactcctccatcttagggccccaccacttggatgagtttgtc
cgcgtctgggcagagtacgaccgagctgcatgtggccgcatccattatactgagatgtat
gaaatgctgactctcatgtcaccaccgctaggcctcggcaagagatgtccctccaaagtg
gcatataagaggttggtcctaatgaatatgccagtagctgaggacatgacagtccacttc
acctccacactgatggctctgatccggacagccctggacatcaaaatcgccaaaggtggt
gcagacaggcagcagctagactcggagctgcaaaaggagaccctggccatctggcctcac
ctgtcccagaagatgctagacctgcttgtgcccatgcccaaagcctctgacctgactgtg
ggcaaaatctatgcagcaatgatgatcatggactactataaacagagtaaggtgaagaaa
cagaggcagcagctggaggaacagaaaaatgcacccatgttccagcgaatggagccctca
tctctgcctcaggagatcattgctaatgccaaagccctgccctatctccagcaggacccc
gtttcaggcctgagtggccgtagtggatacccttcaatgagtccactctccccccaggaa
atattccaattggcttgtatggatccagccgatgatggacagttccaggaacatcagtct
ctggagccagaggttagtgaattaaaaagcgtgcagtcctctaaccatggcatctacctt
ccttcggacacccaggagcatacgggatctgggagggcatcttctatgccacgcctgact
gtggatccccaggtggtgacagatactagctccatgagacgttcattttccactattcgg
gataagcgttcaaattcctcctggttggaggaattctccatggagagaagcagtgaaaac
acctacaagtcacgtcgtcggagttaccactcctccctgagactgtcagctcatcgcctg
aattctgactcaggccacaagtctgacacccaccgctcagggggtagagagcggggacga
tcgaaagagcgaaagcatcttctctctcctgatgtctcccgctgcaactcagaggagcga
gggacccaggccgactgggagtccccagagcgccaacagtccaggtctcccagtgaggcc
aggtcacagacccccaacagacagggcacgggctccctgagcgagagctccatcccctcc
atctctgacaccagcaccccaagacgaagtcgccggcagctcccacccgtcccaccaaag
cctcggcccctcctctcctacagctccctgattcgacactccgggagcatctccccgccg
gccgacggaagcgagaggggctccccgctgaccccccaggcgctggagagcacggaggcc
ggcctggcggagccctcgggcccccggcacgggcacgggcaggggcacgggcaggggcac
gggcagcagagccagcactgctccccgcagcgctacatctccgagccctacctggccctg
cacgaagactcccacgcgtcggactgtggcgaggaggagacgctcaccttcgaggccgcc
gtggccaccagcctgggccgctccaacaccatcggctcggccccgccgctgcggcacagc
tggcagatgcccaacgggcactatcggcggcggcggcgcggggggccggggccgggcgtg
atgtgcggggcggtcagcgacctcctgagtgacacggaagaagacgacaagtgctag

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