KEGG   Canis lupus familiaris (dog): 490382
Entry
490382            CDS       T01007                                 
Symbol
PSEN2
Name
(RefSeq) presenilin-2
  KO
K04522  presenilin 2 [EC:3.4.23.-]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa04330  Notch signaling pathway
cfa04722  Neurotrophin signaling pathway
cfa05010  Alzheimer disease
cfa05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    490382 (PSEN2)
 09150 Organismal Systems
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    490382 (PSEN2)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    490382 (PSEN2)
   05022 Pathways of neurodegeneration - multiple diseases
    490382 (PSEN2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:cfa01002]
    490382 (PSEN2)
Peptidases and inhibitors [BR:cfa01002]
 Aspartic peptidases
  Family A22: presenilin family
   490382 (PSEN2)
SSDB
Motif
Pfam: Presenilin DUF6541
Other DBs
NCBI-GeneID: 490382
NCBI-ProteinID: NP_001271394
Ensembl: ENSCAFG00000016039
VGNC: 45086
UniProt: M1V4F1
Position
7:complement(37629753..37654335)
AA seq 448 aa
MLTFMASDSEEEVCDERTSLMSAESPPPRCCQEARQGLEDGENAAQWRSQDSEEDFEDDA
DHYVCGGVPGQPSGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLI
YTPFTEDTPSVGQRLLNSVLNTLIMISVIVAMTIFLVVLYKYRCYKFIHGWLIMSSLMLL
FLFTYIYLGEVLKTYNVAMDYPTLFLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMA
LVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVW
TVGMAKLDPSSQGALQLPYDPEMEEDSYDSFREPSYPEVFEPPLPGYPGDELEEEEERGV
KLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISI
TFGLIFYFSTDNLVRPFMDTLASHQLYI
NT seq 1347 nt   +upstreamnt  +downstreamnt
atgctcacattcatggcctctgacagtgaggaagaagtgtgtgacgagaggacatccctg
atgtcggctgagagccccccgccacgctgctgccaggaggccaggcagggcctggaggat
ggagaaaatgctgcccagtggagaagccaggacagcgaggaggactttgaggatgatgct
gaccactacgtctgcggcggggtacctgggcagccgtcgggcctggaggaggagctgacc
ctcaagtatggggcaaagcacgtgatcatgctctttgtgccggtcaccctgtgcatgatt
gtggtggtggccaccatcaagtccgtgcgcttctacacagagaagaacggacagctcatc
tacacaccattcaccgaggacacgccctctgtgggccagcgcctcctcaactctgtgctc
aacaccctcatcatgatcagcgtcattgtggccatgaccatcttcttggtcgtgctctac
aagtaccgctgctacaagtttatccatggctggttgatcatgtcatccttgatgctcctg
ttccttttcacctatatctacctcggggaagtgcttaagacctacaacgtggccatggac
taccctaccctgttcctgactgtctggaactttggggcagtgggcatggtgtgcatccat
tggaaaggccccttggtgttgcagcaagcctacctcatcatgatcagtgccctcatggcc
ttggtgttcatcaagtacctccccgaatggtctgcctgggtcattctgggcgccatctct
gtgtacgatctagtggctgtgctgtgccccaaagggcctctgaggatgctggtggagacc
gcccaggagagaaacgagcccatatttcctgccctgatatactcctctgccatggtgtgg
acagtgggcatggccaagctggacccctcctcccagggagccctgcagctgccctacgac
ccagagatggaagaagactcgtatgacagttttagggagccctcgtacccggaagtcttt
gagccccccctgcctggttacccaggggacgaactggaggaagaggaggaaaggggcgtg
aagctcggcctgggggacttcatcttctacagtgtgctggtgggcaaggcagcggccaca
ggcagcggggactggaacaccacgctggcgtgcttcgtggccatcctcattggtttgtgt
ctgaccctcctgctgcttgctgtgttcaagaaggcactgcctgccctccccatttccatc
acatttgggctcatcttttacttctccacggacaacttggtgcgtccgttcatggatacc
ttggcctcccatcagctctacatctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (6)   
   UniProt (1)   
   RefSeq(pep) (5)   
DNA sequence (15)   
   RefSeq(nuc) (5)   
   GenBank (5)   
   EMBL (5)   
Protein domain (2)   
   Pfam (2)   
All databases (39)   

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