KEGG   Camelus ferus (Wild Bactrian camel): 102509058
Entry
102509058         CDS       T02979                                 
Symbol
PLCB2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X3
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
cfr  Camelus ferus (Wild Bactrian camel)
Pathway
cfr00562  Inositol phosphate metabolism
cfr01100  Metabolic pathways
cfr04015  Rap1 signaling pathway
cfr04020  Calcium signaling pathway
cfr04022  cGMP-PKG signaling pathway
cfr04062  Chemokine signaling pathway
cfr04070  Phosphatidylinositol signaling system
cfr04071  Sphingolipid signaling pathway
cfr04072  Phospholipase D signaling pathway
cfr04261  Adrenergic signaling in cardiomyocytes
cfr04270  Vascular smooth muscle contraction
cfr04310  Wnt signaling pathway
cfr04371  Apelin signaling pathway
cfr04540  Gap junction
cfr04611  Platelet activation
cfr04613  Neutrophil extracellular trap formation
cfr04621  NOD-like receptor signaling pathway
cfr04713  Circadian entrainment
cfr04720  Long-term potentiation
cfr04723  Retrograde endocannabinoid signaling
cfr04724  Glutamatergic synapse
cfr04725  Cholinergic synapse
cfr04726  Serotonergic synapse
cfr04728  Dopaminergic synapse
cfr04730  Long-term depression
cfr04742  Taste transduction
cfr04750  Inflammatory mediator regulation of TRP channels
cfr04911  Insulin secretion
cfr04912  GnRH signaling pathway
cfr04915  Estrogen signaling pathway
cfr04916  Melanogenesis
cfr04918  Thyroid hormone synthesis
cfr04919  Thyroid hormone signaling pathway
cfr04921  Oxytocin signaling pathway
cfr04922  Glucagon signaling pathway
cfr04924  Renin secretion
cfr04925  Aldosterone synthesis and secretion
cfr04926  Relaxin signaling pathway
cfr04927  Cortisol synthesis and secretion
cfr04928  Parathyroid hormone synthesis, secretion and action
cfr04929  GnRH secretion
cfr04933  AGE-RAGE signaling pathway in diabetic complications
cfr04934  Cushing syndrome
cfr04935  Growth hormone synthesis, secretion and action
cfr04961  Endocrine and other factor-regulated calcium reabsorption
cfr04970  Salivary secretion
cfr04971  Gastric acid secretion
cfr04972  Pancreatic secretion
cfr04973  Carbohydrate digestion and absorption
cfr05010  Alzheimer disease
cfr05016  Huntington disease
cfr05017  Spinocerebellar ataxia
cfr05022  Pathways of neurodegeneration - multiple diseases
cfr05142  Chagas disease
cfr05143  African trypanosomiasis
cfr05146  Amoebiasis
cfr05163  Human cytomegalovirus infection
cfr05200  Pathways in cancer
cfr05415  Diabetic cardiomyopathy
cfr05417  Lipid and atherosclerosis
Module
cfr_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:cfr00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    102509058 (PLCB2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    102509058 (PLCB2)
   04310 Wnt signaling pathway
    102509058 (PLCB2)
   04371 Apelin signaling pathway
    102509058 (PLCB2)
   04020 Calcium signaling pathway
    102509058 (PLCB2)
   04070 Phosphatidylinositol signaling system
    102509058 (PLCB2)
   04072 Phospholipase D signaling pathway
    102509058 (PLCB2)
   04071 Sphingolipid signaling pathway
    102509058 (PLCB2)
   04022 cGMP-PKG signaling pathway
    102509058 (PLCB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    102509058 (PLCB2)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    102509058 (PLCB2)
   04613 Neutrophil extracellular trap formation
    102509058 (PLCB2)
   04621 NOD-like receptor signaling pathway
    102509058 (PLCB2)
   04062 Chemokine signaling pathway
    102509058 (PLCB2)
  09152 Endocrine system
   04911 Insulin secretion
    102509058 (PLCB2)
   04922 Glucagon signaling pathway
    102509058 (PLCB2)
   04929 GnRH secretion
    102509058 (PLCB2)
   04912 GnRH signaling pathway
    102509058 (PLCB2)
   04915 Estrogen signaling pathway
    102509058 (PLCB2)
   04921 Oxytocin signaling pathway
    102509058 (PLCB2)
   04926 Relaxin signaling pathway
    102509058 (PLCB2)
   04935 Growth hormone synthesis, secretion and action
    102509058 (PLCB2)
   04918 Thyroid hormone synthesis
    102509058 (PLCB2)
   04919 Thyroid hormone signaling pathway
    102509058 (PLCB2)
   04928 Parathyroid hormone synthesis, secretion and action
    102509058 (PLCB2)
   04916 Melanogenesis
    102509058 (PLCB2)
   04924 Renin secretion
    102509058 (PLCB2)
   04925 Aldosterone synthesis and secretion
    102509058 (PLCB2)
   04927 Cortisol synthesis and secretion
    102509058 (PLCB2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102509058 (PLCB2)
   04270 Vascular smooth muscle contraction
    102509058 (PLCB2)
  09154 Digestive system
   04970 Salivary secretion
    102509058 (PLCB2)
   04971 Gastric acid secretion
    102509058 (PLCB2)
   04972 Pancreatic secretion
    102509058 (PLCB2)
   04973 Carbohydrate digestion and absorption
    102509058 (PLCB2)
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    102509058 (PLCB2)
  09156 Nervous system
   04724 Glutamatergic synapse
    102509058 (PLCB2)
   04725 Cholinergic synapse
    102509058 (PLCB2)
   04728 Dopaminergic synapse
    102509058 (PLCB2)
   04726 Serotonergic synapse
    102509058 (PLCB2)
   04720 Long-term potentiation
    102509058 (PLCB2)
   04730 Long-term depression
    102509058 (PLCB2)
   04723 Retrograde endocannabinoid signaling
    102509058 (PLCB2)
  09157 Sensory system
   04742 Taste transduction
    102509058 (PLCB2)
   04750 Inflammatory mediator regulation of TRP channels
    102509058 (PLCB2)
  09159 Environmental adaptation
   04713 Circadian entrainment
    102509058 (PLCB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102509058 (PLCB2)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    102509058 (PLCB2)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    102509058 (PLCB2)
   05142 Chagas disease
    102509058 (PLCB2)
   05143 African trypanosomiasis
    102509058 (PLCB2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102509058 (PLCB2)
   05016 Huntington disease
    102509058 (PLCB2)
   05017 Spinocerebellar ataxia
    102509058 (PLCB2)
   05022 Pathways of neurodegeneration - multiple diseases
    102509058 (PLCB2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102509058 (PLCB2)
   05415 Diabetic cardiomyopathy
    102509058 (PLCB2)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    102509058 (PLCB2)
   04934 Cushing syndrome
    102509058 (PLCB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:cfr04131]
    102509058 (PLCB2)
Enzymes [BR:cfr01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     102509058 (PLCB2)
Membrane trafficking [BR:cfr04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    102509058 (PLCB2)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    102509058 (PLCB2)
SSDB
Motif
Pfam: PI-PLC-X PH_14 PI-PLC-Y EF-hand_like C2
Other DBs
NCBI-GeneID: 102509058
NCBI-ProteinID: XP_014407755
UniProt: A0A8B7K4Y2
Position
6:23092458..23111705
AA seq 817 aa
MSLLNPVLLPPKVKAYLSQGERFIKWDDETTIASPVILRVDPKGYYLYWTYQSKEMEFLD
ITSIRDTRFGKFAKLPKSQKLRDVFNMDFPDNNFLLKTLTVVSGPDMVDLTFHNFVSYKE
NVGKNWAEDVLALVKHPLTANASRLTFLDKILVKLKMQLNPEGKIPVKNFFQIFPADRKR
VEAALSTCHLPKGKNDAINPEDFPESVYKSFLMSLCPRPEIDEIFTSYHAKAKPYMTKEH
LTKFINQKQRDSRLNSLLFPPARPDQVQGLIDKYEPSGINIQRGQLSPEGMVWFLCGPEN
SVLAQDKLLLHHDMTQPLNHYFINSSHNTYLTGGQFSGLSSAEMYRQVLLAGCRCVELDC
WKGKPTDEEPIITHGFTMTTDIYFKEAIEAIAESAFKTSPYPVILSFENHVDSPRQQAKM
AEYCRTIFGDMLLTEPLEKFPLNPGVPLPSPEDLRGKILIKNKKNQFSSPAAPSKEPDGD
AEGSGPPSAPVGEDTVLREAVWTGEEGAELEDEEVEEEEEEESGNLDEEEMKKMQSDEGT
AGLEVTAYKEMSSLVNYIQPTKFISFEFSAQKNRSYVISSFTELKAYDLLSKASVQFVDY
NKRQMSRIYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMALFEFNGQSGYL
LKHEFMRRPDKQFNPFSVDRIDVVVATTLSITVISGQFLSERSVRTYVEVELFGLPGDTK
RRYRTKPSPTTNSINPVWKEEPFVFEKILMPELASLRVAVMEEGNKFLGHRIIPINALNS
GYHHLCLHSESNMPLTMPALFVFLEMKDYVPDTWAGP
NT seq 2454 nt   +upstreamnt  +downstreamnt
atgtctctgctcaaccctgtcctgctgcccccaaaggtgaaggcttatctgagccaaggg
gagcgcttcatcaaatgggacgatgaaacgacaatagcctccccagttattctccgtgtg
gaccccaagggctactacttatactggacatatcagagtaaggagatggagtttctggat
atcaccagcatccgggacacccgctttgggaagtttgccaagctgcccaagagccagaag
ctccgggatgtcttcaacatggactttcctgacaacaacttcctgctgaagacactcact
gtggtgtccggccctgacatggtggatctaaccttccataacttcgtctcctacaaggag
aacgtgggcaagaactgggccgaagatgtactggccctggtcaagcacccgctgacggcc
aacgcctcccgcctcacctttctggacaagatcctggtgaagctcaagatgcagctcaac
cccgaggggaagattcccgtgaagaattttttccagatatttcctgctgaccgcaagcgg
gtagaagctgctctgagcacctgccacctcccaaaaggcaagaatgatgccatcaatcct
gaggacttcccagaatctgtctacaagagttttctcatgagcctctgtcctcggccagaa
atagatgagatcttcacttcctaccacgccaaggccaaaccctacatgaccaaggagcac
ctgaccaaattcatcaaccagaaacagcgcgactcccggctcaactccttgctgttcccg
ccggcgcggcctgaccaggtgcagggtctcatcgacaagtacgagcccagcggcattaac
atacagaggggccagctgtcacccgagggcatggtgtggtttctctgcgggccagagaac
agtgtgctggcccaggacaagctgctgctgcaccacgacatgacgcagccgctcaaccat
tacttcatcaactcctcacacaacacctacctgacaggtggccagttctcaggcctctcc
tctgctgagatgtaccgccaggtgctgctggccggctgccgctgtgtggagctggactgc
tggaaggggaagcctaccgacgaggagcccatcatcacccatggcttcaccatgaccaca
gacatctatttcaaggaagcaattgaagctattgcagaaagtgcctttaagacctcccct
tatccagtcatcctgtcatttgaaaaccacgtggattcaccccgccaacaggctaagatg
gctgagtattgccggacgatatttggggatatgctgctcacagagcccctggaaaagttc
ccactgaacccaggcgtccccctgcccagtcctgaggatctccgaggcaagatcctcatc
aagaacaagaagaaccagttttctagcccagcagctcccagcaaagagccagatggggat
gctgaagggagcggcccacccagtgcccctgtgggagaggacacagtgctgagggaggca
gtgtggactggtgaggaaggggctgagttggaggacgaggaggtggaagaggaagaggag
gaggagtcgggaaacctggatgaagaggagatgaagaagatgcagtcagatgagggcaca
gcgggcctggaggtgacagcttacaaggagatgtccagcttagtcaattacatccagcct
accaagttcatctctttcgagttctctgcccagaagaaccgaagttatgtcatctcctcc
ttcacagagctcaaggcttatgacctgctctccaaggcctccgtgcagtttgtggactac
aacaagcggcagatgagccgcatctaccccaagggcacccgcatggactcctccaactat
atgccccagatgttctggaatgccggttgtcagatggttgctctcaacttccagacaatg
gacctgcccatgcagcagaacatggcactcttcgaattcaatgggcagagtggttacctc
ctcaagcatgagttcatgcgtcggccggacaagcagttcaaccccttctcagtggaccgc
attgacgtggtggtagccaccaccctttccattacggtgatctctgggcagttcctgtca
gagcgcagtgtgcgcacctatgtggaagtggagctgtttggccttcctggagacaccaag
aggcgctatcggaccaagccgtcacccactaccaactccatcaatcctgtctggaaggag
gagccctttgtctttgagaagatcttaatgcctgagctggcttccctcagggtggctgtg
atggaggaaggcaacaagtttcttggacatcgcatcatccccatcaatgccctgaattct
ggataccaccatctgtgcctgcacagtgagagcaacatgcccctcaccatgcctgcgctc
tttgtcttcctagagatgaaggactatgtacctgacacctgggcaggcccatga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (61)   
   KEGG PATHWAY (60)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (5)   
   RefSeq(nuc) (5)   
Protein domain (5)   
   Pfam (5)   
All databases (98)   

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