KEGG   Camelus ferus (Wild Bactrian camel): 102518322
Entry
102518322         CDS       T02979                                 
Symbol
RPS6KB2
Name
(RefSeq) LOW QUALITY PROTEIN: ribosomal protein S6 kinase beta-2
  KO
K04688  ribosomal protein S6 kinase beta [EC:2.7.11.1]
Organism
cfr  Camelus ferus (Wild Bactrian camel)
Pathway
cfr01521  EGFR tyrosine kinase inhibitor resistance
cfr01522  Endocrine resistance
cfr04012  ErbB signaling pathway
cfr04066  HIF-1 signaling pathway
cfr04140  Autophagy - animal
cfr04150  mTOR signaling pathway
cfr04151  PI3K-Akt signaling pathway
cfr04152  AMPK signaling pathway
cfr04211  Longevity regulating pathway
cfr04213  Longevity regulating pathway - multiple species
cfr04350  TGF-beta signaling pathway
cfr04371  Apelin signaling pathway
cfr04666  Fc gamma R-mediated phagocytosis
cfr04714  Thermogenesis
cfr04910  Insulin signaling pathway
cfr04931  Insulin resistance
cfr05163  Human cytomegalovirus infection
cfr05165  Human papillomavirus infection
cfr05170  Human immunodeficiency virus 1 infection
cfr05200  Pathways in cancer
cfr05205  Proteoglycans in cancer
cfr05207  Chemical carcinogenesis - receptor activation
cfr05210  Colorectal cancer
cfr05212  Pancreatic cancer
cfr05221  Acute myeloid leukemia
cfr05224  Breast cancer
cfr05225  Hepatocellular carcinoma
cfr05226  Gastric cancer
cfr05231  Choline metabolism in cancer
cfr05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:cfr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    102518322 (RPS6KB2)
   04350 TGF-beta signaling pathway
    102518322 (RPS6KB2)
   04371 Apelin signaling pathway
    102518322 (RPS6KB2)
   04066 HIF-1 signaling pathway
    102518322 (RPS6KB2)
   04151 PI3K-Akt signaling pathway
    102518322 (RPS6KB2)
   04152 AMPK signaling pathway
    102518322 (RPS6KB2)
   04150 mTOR signaling pathway
    102518322 (RPS6KB2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    102518322 (RPS6KB2)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    102518322 (RPS6KB2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    102518322 (RPS6KB2)
  09149 Aging
   04211 Longevity regulating pathway
    102518322 (RPS6KB2)
   04213 Longevity regulating pathway - multiple species
    102518322 (RPS6KB2)
  09159 Environmental adaptation
   04714 Thermogenesis
    102518322 (RPS6KB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102518322 (RPS6KB2)
   05205 Proteoglycans in cancer
    102518322 (RPS6KB2)
   05207 Chemical carcinogenesis - receptor activation
    102518322 (RPS6KB2)
   05231 Choline metabolism in cancer
    102518322 (RPS6KB2)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    102518322 (RPS6KB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    102518322 (RPS6KB2)
   05212 Pancreatic cancer
    102518322 (RPS6KB2)
   05225 Hepatocellular carcinoma
    102518322 (RPS6KB2)
   05226 Gastric cancer
    102518322 (RPS6KB2)
   05221 Acute myeloid leukemia
    102518322 (RPS6KB2)
   05224 Breast cancer
    102518322 (RPS6KB2)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    102518322 (RPS6KB2)
   05163 Human cytomegalovirus infection
    102518322 (RPS6KB2)
   05165 Human papillomavirus infection
    102518322 (RPS6KB2)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    102518322 (RPS6KB2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    102518322 (RPS6KB2)
   01522 Endocrine resistance
    102518322 (RPS6KB2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cfr01001]
    102518322 (RPS6KB2)
Enzymes [BR:cfr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     102518322 (RPS6KB2)
Protein kinases [BR:cfr01001]
 Serine/threonine kinases: AGC group
  RSK family [OT]
   102518322 (RPS6KB2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Pkinase_C Kinase-like Pkinase_fungal ABC1 Seadorna_VP7
Other DBs
NCBI-GeneID: 102518322
NCBI-ProteinID: XP_006176045
UniProt: A0A8B6Y864
Position
10:67252634..67258901
AA seq 485 aa
MAAVFDLDLETEEGSEGEGEPELSSADVCPLAELRAAGLEPVGHYEEVELTETSVNPGPE
RIGPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVCNAKDTAHTRAER
NILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLSEITL
ALGHLHSQGIIYRDLKPENIMLNSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEI
LVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIKGKLALPPYLTPDARDLV
KKFLKRNPSQRIGGGPGDAAEVQRHPFFRHINWDDLLARRMDPPFRPCLQSEEDVSQFDS
HFTRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRSPRRLNSSPRT
PISPLKFSPFEGFRPSPGPPEPMEPPLPPLLPAPPPPPPSSTAPLPIRPPSGTKKSKRGR
GRPGR
NT seq 1458 nt   +upstreamnt  +downstreamnt
atggcggcggtgtttgacctggacctggagactgaggaaggcagcgagggcgagggcgag
ccagagttaagctccgcggacgtgtgcccccttgccgagttgagggcagctggcctggag
ccagtgggacactatgaggaggtggagttgactgaaaccagtgtgaacccgggccctgag
cgcattggaccccactgctttgagctgctgcgtgtgctagggaaggggggctacggcaag
gtgttccaggtgcgaaaggtgcagggcaccaatctgggcaaaatatatgccatgaaagtc
ttaaggaaggccaagattgtgtgcaacgccaaggacacggcacatacacgggctgagcgg
aacattctagagtcagtgaagcatcccttcattgtggaactggcctatgccttccaaact
ggcggcaaactctacctcatccttgagtgcctcagtggtggtgagctcttcacacatctg
gagcgagagggcatcttcctggaagacacggcctgtttctacctgtcagagatcacactg
gccctgggccatctccactcccaaggcatcatctaccgggacctcaagcctgagaacatc
atgctcaacagccagggccacatcaaactgaccgactttggactgtgcaaggagtcgatt
cacgagggcgccgtcacccacaccttctgtggcaccatcgagtacatggcccctgagatt
ctggtgcgcagtggccacaaccgggcggtggactggtggagcttgggcgccctgatgtac
gacatgctcactggatcgccacccttcactgcagagaaccggaagaagaccatggacaag
atcatcaaagggaagctggctctgcccccctacctcaccccggatgcccgggacctcgtc
aaaaagtttctgaagcggaatcccagccaacggattgggggtggcccaggagacgctgct
gaggtgcagcggcaccccttcttccggcacattaattgggacgacctcctggcccgccgc
atggacccccctttccggccctgtctgcagtcagaggaagacgtgagccagtttgactcc
cacttcacaaggcagacaccagtggacagtccagacgacacggcactcagtgagagtgcc
aaccaggccttcctgggcttcacgtacgtggcaccctccgtgctggacagcatcaaagag
ggcttctccttccagcccaagctgcgctcccccaggcgcctcaacagcagcccccggacc
cccatcagccccctgaagttttcgccctttgagggattccggcccagccctggcccacca
gaacccatggagcctcctctacctcctctcctgccagcgcccccaccaccgccaccctcg
agcactgcccctctccccatccgacccccctcagggaccaagaagtccaagaggggccgt
gggcgccctgggcgctag

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