KEGG   Cricetulus griseus (Chinese hamster): 100750927Help
Entry
100750927         CDS       T02813                                 

Gene name
Pla2g4a
Definition
(RefSeq) cytosolic phospholipase A2 isoform X1
  KO
K16342  cytosolic phospholipase A2 [EC:3.1.1.4]
Organism
cge  Cricetulus griseus (Chinese hamster)
Pathway
cge00564  Glycerophospholipid metabolism
cge00565  Ether lipid metabolism
cge00590  Arachidonic acid metabolism
cge00591  Linoleic acid metabolism
cge00592  alpha-Linolenic acid metabolism
cge01100  Metabolic pathways
cge04010  MAPK signaling pathway
cge04014  Ras signaling pathway
cge04072  Phospholipase D signaling pathway
cge04217  Necroptosis
cge04270  Vascular smooth muscle contraction
cge04370  VEGF signaling pathway
cge04611  Platelet activation
cge04664  Fc epsilon RI signaling pathway
cge04666  Fc gamma R-mediated phagocytosis
cge04724  Glutamatergic synapse
cge04726  Serotonergic synapse
cge04730  Long-term depression
cge04750  Inflammatory mediator regulation of TRP channels
cge04912  GnRH signaling pathway
cge04913  Ovarian steroidogenesis
cge04921  Oxytocin signaling pathway
cge05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:cge00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    100750927 (Pla2g4a)
   00565 Ether lipid metabolism
    100750927 (Pla2g4a)
   00590 Arachidonic acid metabolism
    100750927 (Pla2g4a)
   00591 Linoleic acid metabolism
    100750927 (Pla2g4a)
   00592 alpha-Linolenic acid metabolism
    100750927 (Pla2g4a)
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    100750927 (Pla2g4a)
   04010 MAPK signaling pathway
    100750927 (Pla2g4a)
   04370 VEGF signaling pathway
    100750927 (Pla2g4a)
   04072 Phospholipase D signaling pathway
    100750927 (Pla2g4a)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    100750927 (Pla2g4a)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100750927 (Pla2g4a)
   04664 Fc epsilon RI signaling pathway
    100750927 (Pla2g4a)
   04666 Fc gamma R-mediated phagocytosis
    100750927 (Pla2g4a)
  09152 Endocrine system
   04912 GnRH signaling pathway
    100750927 (Pla2g4a)
   04913 Ovarian steroidogenesis
    100750927 (Pla2g4a)
   04921 Oxytocin signaling pathway
    100750927 (Pla2g4a)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    100750927 (Pla2g4a)
  09156 Nervous system
   04724 Glutamatergic synapse
    100750927 (Pla2g4a)
   04726 Serotonergic synapse
    100750927 (Pla2g4a)
   04730 Long-term depression
    100750927 (Pla2g4a)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100750927 (Pla2g4a)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    100750927 (Pla2g4a)
Enzymes [BR:cge01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.4  phospholipase A2
     100750927 (Pla2g4a)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: PLA2_B C2
Motif
Other DBs
NCBI-GeneID: 100750927
NCBI-ProteinID: XP_027273215
UniProt: G3GWV5
Position
5
AA seq 749 aa AA seqDB search
MSFIDPYQHIIVEHQYSHKFTVVVLSATKVTKGTFGDMLDTPDPYVELFISTTPDSRKRT
RHFNNDINPVWNETFEFILDPNQENVLEITLMDANYIMDETLGTATFPVSSMKVGEKKEV
PFIFNQVTEMILEMSLEVCSCPDLRFSMALCDQEKAFRQQRKENIKENMKKLLGPKKSEG
LYSTRDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYIAGLSGSTWYMSTLYSH
PDFPEKGPEEINEELMKNVSHNPLLLLTPQKVKRYVESLWKKKSSGQPVTFTDIFGMLIG
ETLIQNRMNTTLSSLKEKVNEARCPLPLFTCLHVKPDVSELMFADWVEFSPYEIGMAKYG
TFMAPDLFGSKFFMGTVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSGSQNKGSTMEEE
LENITAKHIVSNDSSDSDDEAQAPKGTENEDAEREYQNDNQASWVHRMLMALVSDSALFN
TREGRAGKVHNFMLGLNLNTSYPLSPLRDLSSQDSFDDDELDAAVADPDEFERIYEPLDV
KSKKIHVVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDTSPPFKELLLAEKWAKMN
KLPFPKIDPYVFDREGLKECYVFKPKNPDVENDCPTIIHFVLANINFRKYKAPGVPRETK
EEKEIADFDIFDDPESPFSTFNFQYPNQAFKRLHDLMYFNTLNNIDVIKDAIVESIEYRR
QNPSRCSVSLSNVEARKFFNKEFLSKPTA
NT seq 2250 nt NT seq  +upstreamnt  +downstreamnt
atgtcattcatagatccttatcagcacattatagtggaacaccagtattctcataaattc
acagtagtggttctaagtgccaccaaagtaaccaaggggacctttggtgatatgcttgac
actccagatccttatgtggaactcttcatctctacaacccctgacagcaggaaaagaaca
agacacttcaataatgacataaaccctgtgtggaatgagacctttgagttcattttggat
cctaatcaggaaaatgttttggagatcacattgatggatgccaattacatcatggatgaa
accctaggcacagctacatttcccgtatcttctatgaaggtgggagagaagaaagaagtc
ccctttattttcaaccaagtcactgaaatgattctggagatgtctcttgaagtttgctca
tgcccagacctacggttcagcatggctctgtgtgatcaggagaaggctttcagacaacag
aggaaagagaacataaaggagaacatgaagaaactcttgggtccaaaaaagagtgagggg
ctatattctacacgtgatgtgcctgtggtggccattttgggttcaggtgggggtttccgg
gccatggtgggattttctggtgtgatgaaggcgctgtatgaatcggggattttggactgt
gctacctacattgctggtctttctggctccacatggtacatgtcaaccttgtactctcac
cctgattttccagaaaaaggtccagaggagattaacgaagagctaatgaaaaatgttagc
cacaaccctcttttacttctcacaccacaaaaagtgaaaagatatgttgagtctttatgg
aagaagaaaagttctggtcaacctgtcacctttactgacatctttgggatgcttatagga
gaaacactaattcaaaatagaatgaacacaaccctgagtagtttgaaggaaaaggtcaat
gaagcccggtgccctttgcctctcttcacctgtctccatgtcaaacctgacgtgtcagag
ctgatgtttgctgattgggttgaatttagtccatatgagatcggcatggcaaaatacggt
acctttatggctcctgacctatttggaagcaagttttttatgggaacggttgtgaaaaaa
tatgaagaaaatcccttgcatttcctaatgggtgtctggggaagtgccttttccatactg
ttcaacagagtcttgggagtttctggttcacaaaataaaggttctacaatggaggaggaa
ttagaaaacattacggccaagcacattgtgagtaatgacagctctgatagtgatgatgag
gcccaagcacccaaaggcactgagaatgaagatgctgaaagagagtaccaaaatgacaat
caagcaagttgggtccatcggatgctgatggccttggtgagtgactcagcgttattcaat
acccgagaaggacgagcagggaaggtgcacaacttcatgttggggttgaatctcaacacc
tcctatccactgtctcctctgagagacctcagctcccaggattccttcgatgatgatgaa
ctcgatgcagctgtagcagatccggatgaatttgaacggatatatgaaccactagatgtg
aagagcaaaaagattcacgttgtagacagtgggctcacctttaacctgccttatcccttg
attctccgacctcagagaggtgtggatctcatcatctcctttgacttttctgcaaggcca
agtgacacaagccctcctttcaaggaacttctacttgcagagaagtgggctaaaatgaac
aagctcccctttccaaagattgatccttatgtgtttgatcgggaaggattgaaggagtgc
tatgtttttaaacccaagaatcctgatgtggagaacgattgccctaccattatccacttt
gttctggccaacatcaacttcagaaagtacaaggccccaggtgttccaagggaaaccaaa
gaggagaaagaaatagctgactttgacatttttgatgaccccgaatcgccgttttccacc
ttcaactttcagtatccaaatcaagcattcaagaggctacatgatctgatgtacttcaat
actctgaacaacattgacgtgataaaggatgccattgttgagagcattgaatacagaaga
cagaacccatctcgttgctctgtttccctgagtaatgtcgaggcaagaaaattcttcaac
aaggagtttctaagtaaacctacggcgtag

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