KEGG   Cricetulus griseus (Chinese hamster): 100767923
Entry
100767923         CDS       T02813                                 
Symbol
Tph1
Name
(RefSeq) tryptophan 5-hydroxylase 1
  KO
K00502  tryptophan 5-monooxygenase [EC:1.14.16.4]
Organism
cge  Cricetulus griseus (Chinese hamster)
Pathway
cge00380  Tryptophan metabolism
cge00790  Folate biosynthesis
cge01100  Metabolic pathways
cge04726  Serotonergic synapse
Module
cge_M00037  Melatonin biosynthesis, animals, tryptophan => serotonin => melatonin
Brite
KEGG Orthology (KO) [BR:cge00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    100767923 (Tph1)
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    100767923 (Tph1)
 09150 Organismal Systems
  09156 Nervous system
   04726 Serotonergic synapse
    100767923 (Tph1)
Enzymes [BR:cge01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.16.4  tryptophan 5-monooxygenase
     100767923 (Tph1)
SSDB
Motif
Pfam: Biopterin_H ACT TH_ACT zf-C2HE
Other DBs
NCBI-GeneID: 100767923
NCBI-ProteinID: XP_035305421
UniProt: A0A9J7H5U9
Position
9:18166974..18191785
AA seq 444 aa
MIEDNKENKGHSSERGRVTLIFSLKNEVGELIKALKIFQENHVNLLHIESRKSNRRNSEF
EILVDCDINREQLNDIFPLLKSHITMLSVDSPGQLTVKEDVLETVPWFPKKISDLDFCAN
RVLMYGSELDADHPGFKDNVYRRRRKYFAELAMNYKHGDPIPKIEFTEEEIKTWGTIFRE
LNKLYPTHACREYLRNLPLLSKYCDYREDNIPQLEDVSNFLKECTGFSIRPVAGYLSPRD
FLSGLAFRVFHCTQYVRHSSDPLYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGA
SDETVQKLATCYFFTVEFGLCKQDGQLRVFGAGLLSSISELKHAISGHAKVKPFDPKVAC
KQECLITTFQDVYFVSESFEDAKQKMREFTKTVKRPFGVKYNPYTQSIQVLRDAKSITSA
VNDLRYDLDVISDALARVSRQPSV
NT seq 1335 nt   +upstreamnt  +downstreamnt
atgatcgaagacaacaaggagaacaaaggccattcctcagaaagggggagagtgactctc
attttttccttaaagaatgaagttggagagctcataaaagcactgaaaatcttccaggag
aaccacgtgaacttgttacatatcgagtcccggaaatcaaatcgaagaaattcagagttt
gagattcttgttgactgcgacatcaacagagaacagctgaatgacatctttcccctgctg
aagtcccacatcacgatgctctctgtggactcccccggtcagctcactgtaaaggaagat
gttttggagactgttccttggtttccaaagaagatttctgacctggacttctgtgccaac
agagtgctgatgtatggttccgaactcgacgcggatcatcctggcttcaaagataatgtc
taccgtagaagacgaaagtattttgcagagttggctatgaactacaaacatggggatccc
attcccaagattgaatttacggaagaagagattaagacctggggaaccatcttccgagag
ctgaacaaactgtacccgacacacgcctgcagggagtacctcagaaaccttcctctgctc
tcgaaatactgtgactatcgtgaagacaacatcccacaactggaagatgtctccaacttt
ttaaaagaatgtacagggttttccatccgtcctgttgctggttacctctcaccaagagat
ttcctgtcagggttagcctttcgagtctttcactgcactcagtatgtgagacacagttca
gatcccctctatactccagagccagatacctgccatgaactcttaggtcatgttcctctc
ttggctgaacccagttttgctcaattctcccaagaaatcggcctggcatcccttggagct
tcagatgagactgttcaaaaactggcaacgtgctacttttttactgtggagtttggtctg
tgcaaacaagatggacagctgagagtctttggcgctggcttgctttcttccatcagtgag
ctcaaacatgcaatttctggacatgccaaagttaagccctttgatcccaaggttgcctgc
aagcaggagtgtctcatcacaaccttccaggatgtctactttgtatctgagagctttgaa
gatgcaaagcagaagatgagagaatttactaaaacagtgaagcgcccatttggagtgaag
tacaatccgtacactcagagcatccaggttctgagagatgccaagagcataaccagtgct
gtgaatgacttgcggtatgaccttgatgtcatcagtgatgcccttgctagagtcagcagg
cagcccagtgtgtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (4)   
   Pfam (4)   
All databases (34)   

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