KEGG   Callithrix jacchus (white-tufted-ear marmoset): 100393460Help
Entry
100393460         CDS       T03264                                 

Gene name
PTEN
Definition
(RefSeq) phosphatase and tensin homolog
  KO
K01110  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
Organism
cjc  Callithrix jacchus (white-tufted-ear marmoset)
Pathway
cjc00562  Inositol phosphate metabolism
cjc01100  Metabolic pathways
cjc01521  EGFR tyrosine kinase inhibitor resistance
cjc04068  FoxO signaling pathway
cjc04070  Phosphatidylinositol signaling system
cjc04071  Sphingolipid signaling pathway
cjc04115  p53 signaling pathway
cjc04140  Autophagy - animal
cjc04150  mTOR signaling pathway
cjc04151  PI3K-Akt signaling pathway
cjc04218  Cellular senescence
cjc04510  Focal adhesion
cjc04931  Insulin resistance
cjc05165  Human papillomavirus infection
cjc05166  Human T-cell leukemia virus 1 infection
cjc05200  Pathways in cancer
cjc05206  MicroRNAs in cancer
cjc05213  Endometrial cancer
cjc05214  Glioma
cjc05215  Prostate cancer
cjc05218  Melanoma
cjc05222  Small cell lung cancer
cjc05224  Breast cancer
cjc05225  Hepatocellular carcinoma
cjc05230  Central carbon metabolism in cancer
cjc05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:cjc00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100393460 (PTEN)
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    100393460 (PTEN)
   04070 Phosphatidylinositol signaling system
    100393460 (PTEN)
   04071 Sphingolipid signaling pathway
    100393460 (PTEN)
   04151 PI3K-Akt signaling pathway
    100393460 (PTEN)
   04150 mTOR signaling pathway
    100393460 (PTEN)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    100393460 (PTEN)
  09143 Cell growth and death
   04115 p53 signaling pathway
    100393460 (PTEN)
   04218 Cellular senescence
    100393460 (PTEN)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100393460 (PTEN)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100393460 (PTEN)
   05206 MicroRNAs in cancer
    100393460 (PTEN)
   05230 Central carbon metabolism in cancer
    100393460 (PTEN)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100393460 (PTEN)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    100393460 (PTEN)
   05214 Glioma
    100393460 (PTEN)
   05218 Melanoma
    100393460 (PTEN)
   05215 Prostate cancer
    100393460 (PTEN)
   05213 Endometrial cancer
    100393460 (PTEN)
   05224 Breast cancer
    100393460 (PTEN)
   05222 Small cell lung cancer
    100393460 (PTEN)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    100393460 (PTEN)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100393460 (PTEN)
   05165 Human papillomavirus infection
    100393460 (PTEN)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100393460 (PTEN)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:cjc01009]
    100393460 (PTEN)
Enzymes [BR:cjc01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     100393460 (PTEN)
    3.1.3.48  protein-tyrosine-phosphatase
     100393460 (PTEN)
    3.1.3.67  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
     100393460 (PTEN)
Protein phosphatases and associated proteins [BR:cjc01009]
 Protein Tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   Phosphatase and Tensin homologs (PTEN)
    100393460 (PTEN)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: PTEN_C2 DSPc Y_phosphatase Y_phosphatase3 PTPlike_phytase DUF3256
Motif
Other DBs
NCBI-GeneID: 100393460
NCBI-ProteinID: XP_017834606
Ensembl: ENSCJAG00000005322
UniProt: U3F9J7
Position
12
AA seq 403 aa AA seqDB search
MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSK
HKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVA
AIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSY
LLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMY
FEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEI
DSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEAS
SSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV
NT seq 1212 nt NT seq  +upstreamnt  +downstreamnt
atgacagccatcatcaaagagatcgttagcagaaacaaaaggagatatcaagaggatgga
ttcgacttagacttgacctatatttatccaaacattattgctatgggatttcctgcagaa
agacttgaaggcgtatacaggaacaatattgatgatgtagtaaggtttttggattcaaag
cataaaaaccattacaagatatacaatctttgtgctgaaagacattatgacaccgccaaa
tttaattgcagagttgcacaatatccttttgaagaccataacccaccacagctagaactt
atcaaacccttttgcgaagatcttgaccaatggctaagtgaagatgacaatcatgttgca
gcaattcactgtaaagctggaaagggacgaactggtgtaatgatttgtgcatatttatta
catcggggcaaatttttaaaggcacaagaggctctagatttctatggggaagtaaggacc
agagacaaaaagggagtaactattcccagtcagaggcgctatgtgtattattatagctac
ctgttaaagaatcatctggattatagaccagtggcactgttgtttcacaagatgatgttt
gaaactattccaatgttcagtggcggaacttgcaatcctcagtttgtggtctgccagcta
aaggtgaagatatattcctccaattcaggacccacacgacgggaagacaagtttatgtac
tttgagttccctcagccgttacctgtgtgtggtgatatcaaagtagagttcttccacaaa
cagaacaagatgctaaaaaaggacaaaatgtttcacttttgggtaaatacattcttcata
ccaggaccagaagaaacctcagaaaaagtagaaaatggaagtctatgtgatcaagaaatt
gatagcatttgcagtatagaacgtgcagataatgacaaggaatatctagtacttacttta
acaaaaaatgatctggataaagcaaataaagacaaagccaaccgatacttttctccaaat
tttaaggtgaagctgtacttcacaaaaacagtagaggagccgtcaaatccagaggctagc
agttcaacttctgtaacaccagatgttagtgacaatgaacctgatcattatagatattct
gacaccactgactctgatccagagaatgaaccttttgatgaagatcagcatacacaaatt
acaaaagtctga

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