KEGG   Callithrix jacchus (white-tufted-ear marmoset): 100398593
Entry
100398593         CDS       T03264                                 
Symbol
MAP2K3
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 3 isoform X2
  KO
K04432  mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
Organism
cjc  Callithrix jacchus (white-tufted-ear marmoset)
Pathway
cjc04010  MAPK signaling pathway
cjc04015  Rap1 signaling pathway
cjc04218  Cellular senescence
cjc04620  Toll-like receptor signaling pathway
cjc04664  Fc epsilon RI signaling pathway
cjc04668  TNF signaling pathway
cjc04714  Thermogenesis
cjc04750  Inflammatory mediator regulation of TRP channels
cjc04912  GnRH signaling pathway
cjc04935  Growth hormone synthesis, secretion and action
cjc04936  Alcoholic liver disease
cjc05014  Amyotrophic lateral sclerosis
cjc05022  Pathways of neurodegeneration - multiple diseases
cjc05132  Salmonella infection
cjc05135  Yersinia infection
cjc05145  Toxoplasmosis
cjc05161  Hepatitis B
cjc05169  Epstein-Barr virus infection
cjc05170  Human immunodeficiency virus 1 infection
cjc05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
cjc05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cjc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100398593 (MAP2K3)
   04015 Rap1 signaling pathway
    100398593 (MAP2K3)
   04668 TNF signaling pathway
    100398593 (MAP2K3)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    100398593 (MAP2K3)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100398593 (MAP2K3)
   04664 Fc epsilon RI signaling pathway
    100398593 (MAP2K3)
  09152 Endocrine system
   04912 GnRH signaling pathway
    100398593 (MAP2K3)
   04935 Growth hormone synthesis, secretion and action
    100398593 (MAP2K3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100398593 (MAP2K3)
  09159 Environmental adaptation
   04714 Thermogenesis
    100398593 (MAP2K3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100398593 (MAP2K3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100398593 (MAP2K3)
   05161 Hepatitis B
    100398593 (MAP2K3)
   05169 Epstein-Barr virus infection
    100398593 (MAP2K3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100398593 (MAP2K3)
   05135 Yersinia infection
    100398593 (MAP2K3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100398593 (MAP2K3)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    100398593 (MAP2K3)
   05022 Pathways of neurodegeneration - multiple diseases
    100398593 (MAP2K3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100398593 (MAP2K3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100398593 (MAP2K3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cjc01001]
    100398593 (MAP2K3)
Enzymes [BR:cjc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     100398593 (MAP2K3)
Protein kinases [BR:cjc01001]
 Serine/threonine kinases: STE group
  STE7 family
   100398593 (MAP2K3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Seadorna_VP7 Haspin_kinase Pkinase_fungal APH Choline_kinase DUF4344 RIO1
Other DBs
NCBI-GeneID: 100398593
NCBI-ProteinID: XP_017824776
Position
5:complement(60749613..60779690)
AA seq 318 aa
MSKPPTPNPTPPRNLDSRTFITIGDRNFEVEADDLVTISELGRGAYGVVEKVRHAQSGTI
MAVKRIRATVNSQEQKRLLMDLDINMRTVDCFYTVTFYGALFREGDVWICMELMDTSLDK
FYRKVLEKGMTIPEDILGEIAVSIVRALEHLHSKLSVIHRDVKPSNVLINKEGHVKMCDF
GISGYLVDSVAKTMDAGCKPYMAPERINPELNQKGYNVKSDVWSLGITMIEMAILRFPYE
SWGTPFQQLKQVVEEPSPQLPADRFSPEFVDFTAQCLRKNPAERMSYLELMVHPFFTLHK
TKKTDIAAFVKEILGEDS
NT seq 957 nt   +upstreamnt  +downstreamnt
atgtccaagccgcccacacccaaccccacacccccccggaacctggactcccggaccttc
atcaccattggagacagaaactttgaggtggaggctgatgacttggtgaccatctcagaa
ctggggcgtggagcctatggggtggtggagaaggtgcggcatgcccagagcggcaccatc
atggccgtgaagcggatccgggccaccgtgaactcacaggagcagaagcggctgctcatg
gacctggacatcaacatgcgcacggtcgactgcttctacaccgtcaccttctatggggca
ctattccgagagggagacgtgtggatctgcatggagctcatggacacatccctggacaag
ttctaccggaaggtgctggagaaaggcatgacaattccagaggacatcctcggggagatt
gctgtgtctatcgtgcgggccctggagcatctgcacagcaagctgtcggtgatccacaga
gatgtgaagccctccaatgtccttatcaacaaggagggccatgtgaaaatgtgcgacttt
ggcatcagtggctacttggtggactctgtggccaagacgatggatgccggctgcaagccc
tacatggctcctgagaggatcaacccggagctgaaccagaagggctacaatgtcaagtcc
gacgtctggagcctgggcatcaccatgattgagatggccatcctacgattcccttacgag
tcctgggggaccccgtttcagcagctgaagcaggtggtggaggagccgtccccccagctc
ccagctgaccgtttctcccccgagtttgtggacttcactgcgcagtgcctgaggaagaac
cccgcagagcgaatgagctacctggagctgatggtgcaccccttcttcactttgcacaaa
accaagaagacggacattgctgccttcgtgaaggagatcctgggagaagactcatag

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