KEGG   Callithrix jacchus (white-tufted-ear marmoset): 100400416Help
Entry
100400416         CDS       T03264                                 

Definition
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1-like
  KO
K00070  3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
Organism
cjc  Callithrix jacchus (white-tufted-ear marmoset)
Pathway
cjc00140  Steroid hormone biosynthesis
cjc01100  Metabolic pathways
cjc04913  Ovarian steroidogenesis
cjc04925  Aldosterone synthesis and secretion
cjc04927  Cortisol synthesis and secretion
cjc04934  Cushing syndrome
Module
cjc_M00107  Steroid hormone biosynthesis, cholesterol => prognenolone => progesterone
cjc_M00110  C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
Brite
KEGG Orthology (KO) [BR:cjc00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    100400416
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    100400416
   04925 Aldosterone synthesis and secretion
    100400416
   04927 Cortisol synthesis and secretion
    100400416
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    100400416
Enzymes [BR:cjc01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.145  3beta-hydroxy-Delta5-steroid dehydrogenase
     100400416
 5. Isomerases
  5.3  Intramolecular oxidoreductases
   5.3.3  Transposing C=C bonds
    5.3.3.1  steroid Delta-isomerase
     100400416
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 3Beta_HSD Epimerase NAD_binding_4 GDP_Man_Dehyd Polysacc_synt_2 NAD_binding_10 RmlD_sub_bind NmrA KR Ldh_1_N
Motif
Other DBs
NCBI-GeneID: 100400416
NCBI-ProteinID: XP_017830548
Position
7
AA seq 276 aa AA seqDB search
MGWSCLVTGAGGFLGRRIVRLLVEEKELKEIRALDKTFRPESREEFSKNFPARSRNPSID
LTGVHAELQKKTKLTMLEGDILDESCLKTACQDVTVVIHTASIVDVFGVIHRESIMNVNV
KGTQLLLEACVHASVPVFIYTSTLEVAGPNSYKEVIQNGHEDQPLENMWSAPYPNSKQLA
EKAVLAANGWTLKNGGTLYTCALRPMYIYGEGGPFLSATVNEALHNMGVLPSVGKFSTVN
PVYVGNVAWAHILALRALRDPRNGPKCPRTVLLHLR
NT seq 831 nt NT seq  +upstreamnt  +downstreamnt
atgggctggagctgccttgtgacaggagcaggagggtttctgggtcggaggatcgtccgc
ctcttggtggaggagaaggagctgaaggagatcagggccttggacaagaccttcagaccg
gagtcgagggaggaattttctaaaaacttcccagccagatccagaaatccttccattgac
ctgaccggtgttcacgcagagctccagaagaagaccaagctgacgatgctggaaggagac
attctggatgagtcatgtctgaagacagcctgccaggatgtcacggttgtcatccacaca
gcctctatcgttgatgtctttggtgtcattcacagagagtccatcatgaatgtcaacgtg
aaaggtacccagctcctgttggaagcctgtgtccacgctagtgtgccagtcttcatctac
accagtaccctagaggtggccgggcccaactcctacaaggaagtcatccagaacggtcat
gaagatcagcctctggaaaacatgtggtctgctccctatccaaacagcaaacagcttgct
gagaaggctgtgctggcggctaatgggtggactctgaaaaacggtggcaccttgtacact
tgtgccttaagacccatgtacatctatggggaaggaggcccattcctttctgccacagta
aatgaagccctccacaacatgggggtcctgccaagtgtcggtaagttctccacagtcaac
ccagtgtatgttggcaacgtggcctgggcccacattctggccttgagggccctgcgggac
cccaggaatggccccaagtgtccgaggacagttctattacatctcagatga

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