KEGG   Cryptococcus neoformans var. neoformans JEC21: CNL04820
Entry
CNL04820          CDS       T00243                                 
Name
(RefSeq) methylenetetrahydrofolate reductase (NADPH), putative
  KO
K25004  methylenetetrahydrofolate reductase (NADPH) [EC:1.5.1.53]
Organism
cne  Cryptococcus neoformans var. neoformans JEC21
Pathway
cne00670  One carbon pool by folate
cne01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:cne00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    CNL04820
Enzymes [BR:cne01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.53  methylenetetrahydrofolate reductase (NADPH)
     CNL04820
SSDB
Motif
Pfam: MTHFR
Other DBs
NCBI-GeneID: 3254762
NCBI-ProteinID: XP_568023
UniProt: Q5K8Q9
Position
12:complement(join(349540..349827,349885..350064,350112..350378,350427..350524,350580..350611,350662..351391,351438..351538,351592..351662,351738..351824))
AA seq 617 aa
MKITEKLQKAEKEGRPFWSFEFFPPRTAQGLQNLYDRIERMRDLGPEFIDITWGAGGKNA
DLTNSLVQVCQATIGIETCMHLCCTEMPKEKVEWALREAKSHGCQNILALRGDPVAGTST
WEPTPGGFMNAVDLVRYIHEHYPGDFCVAVAGFPQGHPETPDTPEGRAQEMEWLKAKVDA
GAEFIFTQMFYDTSIFFDWVKRVREAGINVPIIPGIMPIQNWEKFEKWVQRENIIVPSHF
YEALNPVRGDDEKVRQVGTKLVADMCKTILDNKEAGIKGLHIYTLNLEKGARMLLRELGF
EGRREQIAPLPWRPSLTPSRREETIRPIFWANRTRSYLSRTADWDEFPNGRWGDSRSPAY
GDLDGYPVSIGITAPDAYNLWGHPTTSSDLHALFARFCRGDLAKLPWSTQPPASETSLII
EQLAKMNELGYLTINSQPAVDGVRSDDKVHGWGPPGGYVYQKAYLEFFVSPDLLSPLIRR
IEKDPRITYYAVNKQGDLRTNTHSESPNAVTWGVFPGKEIVQPTIVEAVSFIAWKDEAFE
LGLQWAHLYPAESPSRKLITDTMNTSYLVNIVANDFRDGMSIFEPFLLDQTTVRKVVEGV
KGTVEGIVEGVKGVVGA
NT seq 1854 nt   +upstreamnt  +downstreamnt
atgaagatcaccgagaagctgcagaaggctgaaaaggaaggtcgacccttctggagcttt
gaattcttccctccccgaaccgctcagggtttgcaaaacctctatgacaggatcgagcgt
atgagggaccttggtcctgagtttattgacatcacttggggcgccggtggaaagaacgcc
gatcttaccaactctcttgtccaggtctgccaggcaaccattggcatcgaaacttgcatg
cacctttgctgtaccgagatgcccaaggaaaaggtcgaatgggctctcagggaagctaaa
tctcatgggtgtcagaacatccttgccctccgtggcgaccctgtggccggcacatctacg
tgggagcctactcctggtggattcatgaacgccgtcgacctcgtccgatacattcatgag
cattaccccggagatttctgcgttgccgttgccggatttcctcaagggcatccagagact
cccgacactcccgagggcagggcgcaggagatggagtggctgaaagcaaaggttgatgca
ggagccgaatttatctttactcagatgttctacgatacttcaatcttctttgactgggtt
aagcgcgtgagggaggctggcatcaatgttcccatcattcctggtatcatgcctattcag
aactgggaaaagtttgagaaatgggttcaaagggagaatattattgtgccttctcatttc
tatgaggctcttaaccctgttcggggagacgatgaaaaggtgcgacaggttggaacgaag
ctggttgccgatatgtgtaagacaatcttggataacaaggaggctggtatcaagggtttg
cacatctacacattgaacttggaaaagggagcgagaatgttgttgcgagaacttggattc
gagggaaggagagaacaaatagcgccattgccatggaggccaagtttgactcctagccga
agagaggagaccatcaggccaatcttctgggccaatcggacccgctcttacctttccagg
accgctgattgggacgagttccctaacggacgatggggtgattcgcgaagtcctgcatac
ggtgatctcgacggttaccctgtatccatcggtatcactgctcctgacgcgtacaacctt
tggggccacccaaccacgtcctccgacctccacgccctatttgctcgtttctgccgtggc
gacttggccaaacttccctggtccacccaacctcctgcttccgagacgtctctcatcatt
gaacagcttgccaagatgaatgagctcggatacctcaccatcaactctcaaccagcagtg
gatggtgtgaggagcgacgacaaggtgcacggttggggtccacctggcggctatgtctat
cagaaggcttatctcgagttctttgtctctcccgacctgctttctcctttgattaggaga
attgagaaggaccctaggatcacttactatgctgtcaacaaacagggtgatctgaggacc
aacactcacagcgagagccccaacgctgtcacttggggtgtcttccccggcaaggaaatt
gttcaacccaccatcgtggaggcggtctctttcatcgcctggaaagatgaagccttcgaa
ctcggtctgcagtgggctcatctttaccccgccgaatctccttctcgtaaactcatcacc
gacaccatgaacacttcctatctcgtcaacatcgtcgccaatgacttccgagatggcatg
tcgatcttcgagccgttcttgcttgatcagacaactgtcaggaaagtcgtggagggcgtg
aagggtactgttgaggggatcgttgagggtgtgaagggtgtggtcggcgcttag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   RefGene (17)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (1)   
   Pfam (1)   
All databases (37)   

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