Entry
Name
Fumarate;
Fumaric acid;
trans-Butenedioic acid
Formula
C4H4O4
Exact mass
116.0110
Mol weight
116.07
Structure
Mol file KCF file DB search
Remark
Reaction
Pathway
map00250 Alanine, aspartate and glutamate metabolism
map00760 Nicotinate and nicotinamide metabolism
map01060 Biosynthesis of plant secondary metabolites
map01061 Biosynthesis of phenylpropanoids
map01062 Biosynthesis of terpenoids and steroids
map01063 Biosynthesis of alkaloids derived from shikimate pathway
map01064 Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
map01065 Biosynthesis of alkaloids derived from histidine and purine
map01066 Biosynthesis of alkaloids derived from terpenoid and polyketide
map01110 Biosynthesis of secondary metabolites
map01120 Microbial metabolism in diverse environments
map01220 Degradation of aromatic compounds
map05230 Central carbon metabolism in cancer
Module
M00009 Citrate cycle (TCA cycle, Krebs cycle)
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
M00044 Tyrosine degradation, tyrosine => homogentisate
M00148 Succinate dehydrogenase (ubiquinone)
M00149 Succinate dehydrogenase, prokaryotes
M00150 Fumarate reductase, prokaryotes
M00173 Reductive citrate cycle (Arnon-Buchanan cycle)
M00374 Dicarboxylate-hydroxybutyrate cycle
M00376 3-Hydroxypropionate bi-cycle
M00620 Incomplete reductive citrate cycle, acetyl-CoA => oxoglutarate
M00622 Nicotinate degradation, nicotinate => fumarate
M00844 Arginine biosynthesis, ornithine => arginine
M00845 Arginine biosynthesis, glutamate => acetylcitrulline => arginine
Network
nt06016 Phenylalanine and tyrosine metabolism
Enzyme
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303 ]
D DERMATOLOGICALS
D05 ANTIPSORIATICS
D05A ANTIPSORIATICS FOR TOPICAL USE
D05AX Other antipsoriatics for topical use
D05AX01 Fumaric acid
D02308 Fumaric acid (NF)
BRITE hierarchy
Other DBs
KCF data
Show ATOM 8
1 C6a C 20.4406 -15.2590
2 C2b C 21.6516 -15.9610
3 O6a O 19.2297 -15.9610
4 O6a O 20.4406 -13.8609
5 C2b C 22.8684 -15.2590
6 C6a C 24.0794 -15.9610
7 O6a O 25.2903 -15.2590
8 O6a O 24.0794 -17.3591
BOND 7
1 1 2 1
2 1 3 1
3 1 4 2
4 2 5 2
5 5 6 1
6 6 7 1
7 6 8 2