KEGG COMPOUND: C00473

COMPOUND: C00473

Entry

C00473                      Compound

Name

Retinol;
all-trans-Retinol;
Vitamin A;
Vitamin A1

Formula

C20H30O

Exact mass

286.2297

Mol weight

286.45

Structure

Remark

Same as:

D06543

Reaction

R02124 R02366 R02367 R02368 R02369 R07163 R08379 R08387
R11952

Pathway

map00830

Retinol metabolism

map01100

Metabolic pathways

map01240

Biosynthesis of cofactors

map04977

Vitamin digestion and absorption

Enzyme

1.1.1.1 1.1.1.105 1.1.1.300 1.1.1.-
1.3.99.23 1.14.19.53 2.3.1.76 2.3.1.135
3.1.1.-

Brite

Compounds with biological roles [BR:br08001]
Vitamins and cofactors
  Vitamins
   Fat-soluble vitamins
    C00473  Retinol (Vitamin A)
Lipids [BR:br08002]
PR  Prenol lipids
  PR01 Isoprenoids
   PR0109 Retinoids
    C00473  Retinol
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
  A11 VITAMINS
   A11C VITAMIN A AND D, INCL. COMBINATIONS OF THE TWO
    A11CA Vitamin A, plain
     A11CA01 Retinol (vit A)
      D06543  Vitamin A (USP) <JP>
D DERMATOLOGICALS
  D10 ANTI-ACNE PREPARATIONS
   D10A ANTI-ACNE PREPARATIONS FOR TOPICAL USE
    D10AD Retinoids for topical use in acne
     D10AD02 Retinol
      D06543  Vitamin A (USP) <JP>
R RESPIRATORY SYSTEM
  R01 NASAL PREPARATIONS
   R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
    R01AX Other nasal preparations
     R01AX02 Retinol
      D06543  Vitamin A (USP) <JP>
S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01X OTHER OPHTHALMOLOGICALS
    S01XA Other ophthalmologicals
     S01XA02 Retinol
      D06543  Vitamin A (USP) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
3  Agents affecting metabolism
  31  Vitamins
   311  Vitamins A and D preparations
    3111  Synthetic vitamin A preparations
     D06543  Vitamin A (USP)
Classification of Japanese OTC drugs [BR:br08313]
Nourishing tonics and health supplements
  32 Vitamin A based drugs
   D06543  Vitamin A (USP)
  39 Vitamin AD based drugs
   D06543  Vitamin A (USP)
  43 Vitamin containing supplements
   D06543  Vitamin A (USP)
Risk category of Japanese OTC drugs [BR:br08312]
Designated second-class OTC drugs
  Inorganic and organic chemicals
   Retinol
    D06543  Vitamin A (USP)
Second-class OTC drugs
  Inorganic and organic chemicals
   Vitamin A
    D06543  Vitamin A (USP)
Third-class OTC drugs
  Inorganic and organic chemicals
   Vitamin A
    D06543  Vitamin A (USP)
Animal drugs in Japan [BR:br08331]
96  Agents affecting metabolism
  962  Vitamin preparations
   9621  Vitamin A, D and preparations
    C00473  Vitamin A
Drug groups [BR:br08330]
Vitamin and mineral
  DG01604  Retinol derivative
   DG00123  Retinol (vit A)
    D06543  Vitamin A
Metabolizing enzyme substrate
  DG02918  CYP2C8 substrate
   DG00123  Retinol (vit A)
    D06543  Vitamin A
Target-based classification of drugs [BR:br08310]
Nuclear receptors
  Thyroid hormone like receptors
   Retinoic acid receptor (RAR)
    NR1B (RAR)
     D06543  Vitamin A (USP) <JP>
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
  D06543

Other DBs

CAS:	68-26-8 11103-57-4

PubChem:

ChEBI:

LIPIDMAPS:

KNApSAcK:

PDB-CCD:

RTL[PDBj]

NIKKAJI:

J1.417F J203.784J

KCF data

ATOM        21
            1   C1x C    17.6556  -18.6914
            2   C1x C    17.6556  -20.1003
            3   C1x C    18.8757  -20.8047
            4   C2y C    20.0958  -20.1003
            5   C2y C    20.0958  -18.6914
            6   C1z C    18.8757  -17.9870
            7   C1a C    21.3159  -20.8047
            8   C2b C    22.5360  -18.6914
            9   C2b C    21.3159  -17.9870
            10  C2c C    23.7412  -17.9955
            11  C2b C    24.9370  -18.6859
            12  C1a C    20.0958  -17.2825
            13  C1a C    17.6556  -17.2825
            14  C2b C    26.1354  -17.9939
            15  C1a C    23.7413  -16.5784
            16  C2b C    27.3325  -18.6851
            17  C2c C    28.5301  -17.9935
            18  C2b C    29.7278  -18.6849
            19  C1b C    30.9252  -17.9933
            20  O1a O    32.1229  -18.6849
            21  C1a C    28.5302  -16.5783
BOND        21
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 2
            5     5   6 1
            6     1   6 1
            7     4   7 1
            8     8   9 2
            9     5   9 1
            10    8  10 1
            11   10  11 2
            12    6  12 1
            13    6  13 1
            14   11  14 1
            15   10  15 1
            16   14  16 2
            17   16  17 1
            18   17  18 2
            19   18  19 1
            20   19  20 1
            21   17  21 1

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