| Entry |
|
|---|
| Name |
L-Noradrenaline;
Noradrenaline;
Norepinephrine;
Arterenol;
4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol
|
|---|
| Formula |
C8H11NO3
|
|---|
| Exact mass |
169.0739
|
|---|
| Mol weight |
169.18
|
|---|
| Structure |
|
|---|
| Remark |
|
|---|
| Reaction |
|
|---|
| Pathway |
| map04080 | Neuroactive ligand-receptor interaction |
| map04261 | Adrenergic signaling in cardiomyocytes |
| map04270 | Vascular smooth muscle contraction |
| map04923 | Regulation of lipolysis in adipocytes |
| map05207 | Chemical carcinogenesis - receptor activation |
|
|---|
| Module |
| M00042 | Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline |
|
|---|
| Network |
|
|---|
| Enzyme |
|
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| Brite |
Compounds with biological roles [BR:br08001]
Hormones and transmitters
Other hormones
Adrenalines
C00547 Noradrenaline
Neurotransmitters
Biogenic amines
C00547 Norepinephrine; Noradrenaline
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C01 CARDIAC THERAPY
C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
C01CA Adrenergic and dopaminergic agents
C01CA03 Norepinephrine
D00076 Noradrenaline (JP18) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
24 Hormones
245 Adrenal hormone preparations
2451 Epinephrines
D00076 Noradrenaline (JP18); Norepinephrine (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01703 Cardiotonic
DG01699 Catecholamine cardiotonic
DG00212 Norepinephrine
D00076 Noradrenaline
DG01456 Adrenergic receptor agonist
DG00212 Norepinephrine
D00076 Noradrenaline
DG01951 Catecholamine adrenergic receptor agonist
DG00212 Norepinephrine
D00076 Noradrenaline
Metabolizing enzyme substrate
DG01592 COMT substrate
DG00212 Norepinephrine
D00076 Noradrenaline
DG02917 MAO substrate
DG00212 Norepinephrine
D00076 Noradrenaline
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA1
D00076 Noradrenaline (JP18) <JP>
ADRA2
D00076 Noradrenaline (JP18) <JP>
ADRB
D00076 Noradrenaline (JP18) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00076 Noradrenaline
D00076 Noradrenaline injection
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00076
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| Other DBs |
|
|---|
| KCF data |
ATOM 12
1 C8y C 25.1107 -17.0137
2 C8x C 25.1107 -18.4285
3 C8x C 23.8950 -16.3188
4 C1c C 26.3149 -16.3188
5 C8x C 23.8950 -19.1423
6 C8y C 22.6850 -17.0137
7 C1b C 27.5246 -17.0080
8 O1a O 26.3149 -14.9217
9 C8y C 22.6850 -18.4285
10 N1a N 28.7227 -16.3130
11 O1a O 21.4681 -19.1189
12 O1a O 21.4728 -16.3208
BOND 12
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 3 6 2
6 4 7 1
7 4 8 1 #Up
8 5 9 2
9 7 10 1
10 9 11 1
11 6 9 1
12 6 12 1
|
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