Entry |
|
Name |
L-Adrenaline;
(R)-(-)-Adrenaline;
(R)-(-)-Epinephrine;
(R)-(-)-Epirenamine;
(R)-(-)-Adnephrine;
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
|
Formula |
C9H13NO3
|
Exact mass |
183.0895
|
Mol weight |
183.20
|
Structure |
|
Remark |
|
Reaction |
|
Pathway |
map04080 | Neuroactive ligand-receptor interaction |
map04261 | Adrenergic signaling in cardiomyocytes |
map04923 | Regulation of lipolysis in adipocytes |
map05207 | Chemical carcinogenesis - receptor activation |
|
Module |
M00042 | Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline |
|
Network |
|
Enzyme |
|
Brite |
Compounds with biological roles [BR:br08001]
Hormones and transmitters
Other hormones
Adrenalines
C00788 Adrenaline
Neurotransmitters
Biogenic amines
C00788 Epinephrine; Adrenaline
Prodrugs [br08324.html]
C00788
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A01 STOMATOLOGICAL PREPARATIONS
A01A STOMATOLOGICAL PREPARATIONS
A01AD Other agents for local oral treatment
A01AD01 Epinephrine
D00095 Epinephrine (USP/INN) <JP/US>
B BLOOD AND BLOOD FORMING ORGANS
B02 ANTIHEMORRHAGICS
B02B VITAMIN K AND OTHER HEMOSTATICS
B02BC Local hemostatics
B02BC09 Epinephrine
D00095 Epinephrine (USP/INN) <JP/US>
C CARDIOVASCULAR SYSTEM
C01 CARDIAC THERAPY
C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
C01CA Adrenergic and dopaminergic agents
C01CA24 Epinephrine
D00095 Epinephrine (USP/INN) <JP/US>
R RESPIRATORY SYSTEM
R01 NASAL PREPARATIONS
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01AA Sympathomimetics, plain
R01AA14 Epinephrine
D00095 Epinephrine (USP/INN) <JP/US>
R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
R03A ADRENERGICS, INHALANTS
R03AA Alpha- and beta-adrenoreceptor agonists
R03AA01 Epinephrine
D00095 Epinephrine (USP/INN) <JP/US>
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
S01EA Sympathomimetics in glaucoma therapy
S01EA01 Epinephrine
D00095 Epinephrine (USP/INN) <JP/US>
USP drug classification [BR:br08302]
Respiratory Tract/Pulmonary Agents
Bronchodilators, Sympathomimetic
Epinephrine
D00095 Epinephrine (USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
24 Hormones
245 Adrenal hormone preparations
2451 Epinephrines
D00095 Epinephrine (USP/INN); Adrenaline (JP18)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Inorganic and organic chemicals
Adrenaline (Epinephrine)
D00095 Epinephrine (USP/INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01703 Cardiotonic
DG01699 Catecholamine cardiotonic
DG00013 Epinephrine
D00095 Epinephrine
DG01456 Adrenergic receptor agonist
DG00013 Epinephrine
D00095 Epinephrine
DG01951 Catecholamine adrenergic receptor agonist
DG00013 Epinephrine
D00095 Epinephrine
Metabolizing enzyme substrate
DG01592 COMT substrate
DG00013 Epinephrine
D00095 Epinephrine
DG02917 MAO substrate
DG00013 Epinephrine
D00095 Epinephrine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA1
D00095 Epinephrine (USP/INN) <JP/US>
ADRA2
D00095 Epinephrine (USP/INN) <JP/US>
ADRB
D00095 Epinephrine (USP/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00095 Adrenaline
D00095 Adrenaline solution
D00095 Adrenaline injection
New drug approvals in Europe [br08329.html]
European public assessment reports (EPAR) authorised medicine
D00095
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00095
Prodrugs [br08324.html]
D00095
|
Other DBs |
|
KCF data |
ATOM 13
1 C8y C 21.2028 -17.0133
2 C8x C 21.2028 -18.4284
3 C8x C 19.9857 -16.3144
4 C1c C 22.4083 -16.3144
5 C8x C 19.9857 -19.1389
6 C8y C 18.7742 -17.0133
7 C1b C 23.6196 -17.0075
8 O1a O 22.4083 -14.9168
9 C8y C 18.7742 -18.4284
10 N1b N 24.8191 -16.3087
11 O1a O 17.5630 -19.1156
12 O1a O 17.5677 -16.3165
13 C1a C 26.0284 -17.0006
BOND 13
1 1 3 1
2 1 4 1
3 2 5 1
4 3 6 2
5 4 7 1
6 4 8 1 #Up
7 5 9 2
8 7 10 1
9 9 11 1
10 6 9 1
11 6 12 1
12 1 2 2
13 10 13 1
|