 | | COMPOUND: C07080 | |
| Entry |
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| Name |
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| Formula |
C29H33ClN2O2
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| Exact mass |
476.2231
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| Mol weight |
477.03
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| Structure |
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| Remark |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
A07D ANTIPROPULSIVES
A07DA Antipropulsives
A07DA03 Loperamide
D08144 Loperamide (INN)
Risk category of Japanese OTC drugs [BR:br08312]
Designated second-class OTC drugs
Inorganic and organic chemicals
Loperamide
D08144 Loperamide (INN)
Second-class OTC drugs
Inorganic and organic chemicals
Loperamide
D08144 Loperamide (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG00092 Loperamide
D08144 Loperamide
Metabolizing enzyme substrate
DG02918 CYP2C8 substrate
DG00092 Loperamide
D08144 Loperamide
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG00092 Loperamide
D08144 Loperamide
Transporter substrate
DG01665 ABCB1 substrate
DG00092 Loperamide
D08144 Loperamide
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Opioid
OPRM1
D08144 Loperamide (INN)
OPRK1
D08144 Loperamide (INN)
OPRD1
D08144 Loperamide (INN)
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D08144
Drug transporters
D08144
Rx-to-OTC switch list in the USA [br08315.html]
D08144
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| Other DBs |
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| KCF data |
ATOM 34
1 C8x C 23.5200 -23.6600
2 C8x C 23.5200 -24.9900
3 C8x C 24.7100 -25.6900
4 C8x C 25.9000 -24.9900
5 C8y C 25.9000 -23.6600
6 C8x C 24.7100 -23.0300
7 C8x C 28.2100 -24.9900
8 C8y C 28.2100 -23.6600
9 C1d C 27.0200 -23.0300
10 C8x C 29.4000 -25.6900
11 C8x C 30.5200 -24.9900
12 C8x C 30.5200 -23.6600
13 C8x C 29.4000 -23.0300
14 C5a C 23.8000 -21.3500
15 N1c N 22.6800 -22.0500
16 O5a O 23.8000 -20.0200
17 C1b C 27.0200 -21.6300
18 C1b C 28.2800 -20.9300
19 N1y N 28.2800 -19.5300
20 C1x C 29.4700 -18.8300
21 C1x C 29.4700 -17.4300
22 C1z C 28.2800 -16.7300
23 C1x C 27.0200 -17.4300
24 C1x C 27.0200 -18.8300
25 C1a C 21.4200 -21.4200
26 C1a C 22.6800 -23.4500
27 C8y C 28.2800 -15.3300
28 C8x C 29.5400 -14.6300
29 C8x C 29.5400 -13.2300
30 C8y C 28.3500 -12.5300
31 C8x C 27.0900 -13.2300
32 C8x C 27.0900 -14.6300
33 O1a O 29.4700 -16.0300
34 X Cl 28.3500 -11.1300
BOND 37
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 7 8 1
8 8 9 1
9 5 9 1
10 7 10 2
11 10 11 1
12 11 12 2
13 12 13 1
14 8 13 2
15 9 14 1
16 14 15 1
17 14 16 2
18 9 17 1
19 17 18 1
20 18 19 1
21 19 20 1
22 20 21 1
23 21 22 1
24 22 23 1
25 23 24 1
26 19 24 1
27 15 25 1
28 15 26 1
29 22 27 1
30 27 28 2
31 28 29 1
32 29 30 2
33 30 31 1
34 31 32 2
35 27 32 1
36 22 33 1
37 30 34 1
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