KEGG   COMPOUND: C07784Help
Entry
C07784                      Compound                               

Name
Diphenhydramine hydrochloride
Formula
C17H21NO. HCl
Exact mass
291.139
Mol weight
291.8157
Structure
Mol fileKCF fileDB search
Remark
Same as: D00669
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D04 ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
   D04A ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
    D04AA Antihistamines for topical use
     D04AA32 Diphenhydramine
      D00669  Diphenhydramine hydrochloride (JP17/USP) <JP/US>
 R RESPIRATORY SYSTEM
  R06 ANTIHISTAMINES FOR SYSTEMIC USE
   R06A ANTIHISTAMINES FOR SYSTEMIC USE
    R06AA Aminoalkyl ethers
     R06AA02 Diphenhydramine
      D00669  Diphenhydramine hydrochloride (JP17/USP) <JP/US>
USP drug classification [BR:br08302]
 Antiemetics
  Antiemetics, Other
   Diphenhydramine
    D00669  Diphenhydramine hydrochloride (JP17/USP)
 Antiparkinson Agents
  Anticholinergics
   Diphenhydramine
    D00669  Diphenhydramine hydrochloride (JP17/USP)
 Respiratory Tract/Pulmonary Agents
  Antihistamines
   Histamine (H1) Receptor Antagonists, Sedating
    Diphenhydramine
     D00669  Diphenhydramine hydrochloride (JP17/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 4  Agents affecting cellular function
  44  Allergic agents
   441  Antihistamines
    4411  Diphenhydramines
     D00669  Diphenhydramine hydrochloride (JP17/USP)
Classification of Japanese OTC drugs [BR:br08313]
 Agents for nervous and sensory systems
  01 Cold remedy (oral use)
   D00669  Diphenhydramine hydrochloride (JP17/USP)
  04 Sedative hypnotic agents
   D00669  Diphenhydramine hydrochloride (JP17/USP)
  06 Antivertigo drugs (incl. motion/morning sickness remedies)
   D00669  Diphenhydramine hydrochloride (JP17/USP)
 Allergic agents
  52 Antihistamine based drugs
   D00669  Diphenhydramine hydrochloride (JP17/USP)
 Agents for integumentary system
  57 Analgesic, antipruritic, astringent, and anti-inflammatory remedies (incl. gel patches)
   D00669  Diphenhydramine hydrochloride (JP17/USP)
 Agents for ophthalmologic use
  64 Allergy eye drops
   D00669  Diphenhydramine hydrochloride (JP17/USP)
Risk category of Japanese OTC drugs [BR:br08312]
 Designated second-class OTC drugs
  Inorganic and organic chemicals
   Diphenhydramine
    D00669  Diphenhydramine hydrochloride (JP17/USP)
 Second-class OTC drugs
  Inorganic and organic chemicals
   Diphenhydramine
    D00669  Diphenhydramine hydrochloride (JP17/USP)
 Third-class OTC drugs
  Inorganic and organic chemicals
   Diphenhydramine
    D00669  Diphenhydramine hydrochloride (JP17/USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Histamine
    HRH1
     D00669  Diphenhydramine hydrochloride (JP17/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00669  Diphenhydramine hydrochloride
Rx-to-OTC switch list in the USA [br08315.html]
 D00669
Animal drugs in Japan [BR:br08331]
 95  Agents for external use
  953  Analgesics, anti-itchings, astringents and antiinflammatory agents
   9532  Anti-histaminic and preparations
    C07784  Diphenhydramine hydrochloride
  954  Anti-dermoinfectives
   9549  Other anti-dermoinfectives
    C07784  Diphenhydramine hydrochloride
 96  Agents affecting metabolism
  968  Antiallergic agents (including nonspecific antigen preparations)
   9681  Diphenhydramine, derivatives and preparations
    C07784  Diphenhydramine hydrochloride
BRITE hierarchy
Other DBs
CAS: 147-24-0
PubChem: 9986
ChEMBL: CHEMBL1620
KCF data Show

ATOM        20
            1   X   Cl   35.2801  -16.8000
            2   C1c C    28.6548  -15.7456
            3   C8y C    27.4439  -16.4499
            4   C8y C    29.8716  -16.4499
            5   O2a O    28.6607  -14.3484
            6   C8x C    27.4439  -17.8530
            7   C8x C    26.2330  -15.7456
            8   C8x C    29.8659  -17.8530
            9   C8x C    31.0766  -15.7456
            10  C1b C    29.8716  -13.6440
            11  C8x C    26.2330  -18.5456
            12  C8x C    25.0162  -16.4499
            13  C8x C    31.0766  -18.5456
            14  C8x C    32.2933  -16.4499
            15  C8x C    25.0162  -17.8530
            16  C8x C    32.2874  -17.8530
            17  C1b C    31.1075  -14.3550
            18  N1c N    32.3040  -13.6616
            19  C1a C    33.4933  -14.3457
            20  C1a C    32.3018  -12.2527
BOND        20
            1     6  11 2
            2     7  12 1
            3     8  13 1
            4     9  14 2
            5    11  15 1
            6    13  16 2
            7    12  15 2
            8    14  16 1
            9     2   3 1
            10    2   4 1
            11    2   5 1
            12    3   6 1
            13    3   7 2
            14    4   8 2
            15    4   9 1
            16    5  10 1
            17   10  17 1
            18   17  18 1
            19   18  19 1
            20   18  20 1

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