KEGG   Thermoclostridium stercorarium subsp. stercorarium DSM 8532: Cst_c05420
Entry
Cst_c05420        CDS       T02440                                 
Symbol
ligA
Name
(GenBank) NAD-dependend DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
css  Thermoclostridium stercorarium subsp. stercorarium DSM 8532
Pathway
css03030  DNA replication
css03410  Base excision repair
css03420  Nucleotide excision repair
css03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:css00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    Cst_c05420 (ligA)
   03410 Base excision repair
    Cst_c05420 (ligA)
   03420 Nucleotide excision repair
    Cst_c05420 (ligA)
   03430 Mismatch repair
    Cst_c05420 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:css03032]
    Cst_c05420 (ligA)
   03400 DNA repair and recombination proteins [BR:css03400]
    Cst_c05420 (ligA)
Enzymes [BR:css01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     Cst_c05420 (ligA)
DNA replication proteins [BR:css03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     Cst_c05420 (ligA)
DNA repair and recombination proteins [BR:css03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     Cst_c05420 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     Cst_c05420 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     Cst_c05420 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      Cst_c05420 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT DNA_ligase_ZBD HHH_5 BRCT_2 PTCB-BRCT HHH Lar_restr_allev zf-TFIIB Flavoprotein RUBY_RBDX zf-C4_Topoisom
Other DBs
NCBI-ProteinID: AGC67564
UniProt: L7VLP9
Position
576391..578367
AA seq 658 aa
MDEKVVRIKELVNRLNEASKAYYQENREIMSNYEYDKLYDELVELEKETGIVLSNSPTVK
VGYELLSSLPKEAHEQPMLSLDKTKDVNALVEWLGDKKGILSWKLDGLTIVLTYSNGELI
KAVTRGNGEVGEVVTNNAKVFRNLPIRISYKGNLVLRGEAVIRYSDFEKINREIENVDAK
YKNPRNLCSGSVRQLNNRITAERNVYFFAFQIVKVDEPEIGKFRSRQLNWLKSQGFDVVE
FKEVDSSNLEQTVKWFSEQVVKNDFPADGLVLAYDDVEYGRSLGTTAKFPRDSIAFKWQD
EVAETRLIKIEWSASRTGLINPIAIFEPVELEGTTVKRASVHNISVMESLELGIGDTIGV
YKANMIIPQIAYNLTKSGNIEIPEHCPVCGGQTQIRQENGVKFLYCTNGECPAKHIKSLV
HFVSRDAMGIDGLSEATIEKFVEKGFIKDYADIFRLERFRNEIVKMEGFGEKSYSNLISS
INKARKTNAVRLLYSMGIPGIGLSNAKRIAGYFNHEWGRIENATFEELINIDGIGDIMAR
DFVAFFKNERNRERIRELMAEIELEKETASDKSQIFRDITFVITGSVNHFKNRAELKKVI
EERGGRVTESVTSNTNYLINNDINSTSAKNKKAKELGIPIITEEQFLEWLNDGVIPGE
NT seq 1977 nt   +upstreamnt  +downstreamnt
atggacgaaaaagtagtcagaattaaagaactggtaaacaggcttaatgaagcgtctaaa
gcatattaccaggaaaatcgggagataatgtccaattacgagtatgacaaactgtatgat
gaacttgtggaactggaaaaggaaacgggcatagtcctttcaaacagccctacggtgaaa
gtcggatatgagctgctcagcagtctgccgaaagaagcgcatgagcagcccatgctttct
ttggacaagacaaaagacgttaatgcgttggtggaatggctcggcgacaaaaagggaata
ctgtcgtggaaacttgacggtcttaccattgtgcttacatattccaacggtgagcttatt
aaagcggtaacccgcggcaacggtgaagtgggagaagtggttaccaacaatgcgaaggtg
tttaggaatttgcccatcagaatttcctataaaggaaatcttgtgctgagaggggaagct
gttatcagatattcggactttgaaaaaatcaacagggaaattgaaaatgtggacgcaaaa
tataagaatccgagaaatttatgcagcggctcggtcaggcagctcaataacagaataacc
gccgaaaggaatgtatatttttttgcctttcagattgtaaaggttgacgagccggaaata
ggaaaattcaggagcagacagttgaactggcttaaaagccagggctttgatgtggtggaa
tttaaggaagtggactcatcaaacctggaacagaccgttaaatggttctccgaacaggtt
gtaaaaaacgattttcctgccgacggtctggtgcttgcgtatgatgatgtggaatacggg
cgttcccttggcacaacggccaaattccctagagactccattgcttttaagtggcaggat
gaggtagccgaaaccaggctgataaaaattgaatggagcgcctcacggacagggctgatt
aatccaattgcgatttttgaaccggtggagcttgaggggacaacggtaaaacgagccagt
gtacataacatcagtgttatggaatcgctggaacttggaattggagatacgataggcgta
tacaaggcaaatatgataattcctcagatagcgtacaacttaacaaaaagcggaaatatt
gaaattccggaacactgtcctgtatgcggcgggcagacacaaatcaggcaggaaaacgga
gtaaagttcctatattgcaccaacggcgaatgcccggcaaaacatataaagtcgcttgtg
cattttgtcagcagggatgcgatgggaattgacgggctttccgaagccacgatagaaaaa
tttgttgaaaaaggatttattaaggattatgcggacattttcaggctggaaagattcaga
aacgaaatagtgaaaatggaaggattcggggagaagtcgtacagcaatttgataagttca
atcaacaaggcccggaaaaccaatgccgtccgtctcctttacagtatgggcatacccggt
atcggcctttccaatgccaaacgcattgcgggttatttcaatcatgagtggggccgtatt
gaaaacgcaacgtttgaggagttaatcaatattgatggaattggcgatattatggcccgg
gattttgttgccttttttaaaaacgaaagaaacagggaacgaatcagggagcttatggcc
gaaattgagctggagaaggaaacggcgtctgataaaagccagatattcagggatattacc
tttgttattacagggtcggtcaatcattttaagaaccgtgcggaattgaaaaaggtgata
gaagagaggggaggcagggtaaccgagtcggttacgtcaaacaccaattatcttataaat
aatgatataaattcaacttcagcaaaaaataaaaaagcaaaggaattggggattccgatt
ataaccgaggaacagttcctggaatggcttaatgatggagttattcccggcgaatag

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