KEGG   Dickeya dadantii 3937: Dda3937_03889
Entry
Dda3937_03889     CDS       T01305                                 
Symbol
metL
Name
(GenBank) bifunctional aspartokinase/homoserine dehydrogenase
  KO
K12525  bifunctional aspartokinase / homoserine dehydrogenase 2 [EC:2.7.2.4 1.1.1.3]
Organism
ddd  Dickeya dadantii 3937
Pathway
ddd00260  Glycine, serine and threonine metabolism
ddd00261  Monobactam biosynthesis
ddd00270  Cysteine and methionine metabolism
ddd00300  Lysine biosynthesis
ddd01100  Metabolic pathways
ddd01110  Biosynthesis of secondary metabolites
ddd01120  Microbial metabolism in diverse environments
ddd01230  Biosynthesis of amino acids
Module
ddd_M00016  Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
ddd_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
ddd_M00018  Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:ddd00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    Dda3937_03889 (metL)
   00270 Cysteine and methionine metabolism
    Dda3937_03889 (metL)
   00300 Lysine biosynthesis
    Dda3937_03889 (metL)
  09110 Biosynthesis of other secondary metabolites
   00261 Monobactam biosynthesis
    Dda3937_03889 (metL)
Enzymes [BR:ddd01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.3  homoserine dehydrogenase
     Dda3937_03889 (metL)
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.2  Phosphotransferases with a carboxy group as acceptor
    2.7.2.4  aspartate kinase
     Dda3937_03889 (metL)
SSDB
Motif
Pfam: AA_kinase Homoserine_dh NAD_binding_3
Other DBs
NCBI-ProteinID: ADM96415
UniProt: E0SGC9
Position
218864..221299
AA seq 811 aa
MSALGIAAAVKGRQLHKFGGSSLADVKCYQRVAGIMADYSQAGDLMVVSAAGSTTNQLIS
WLNLSQSDRISAHQVQQSLRRYQSELISGLLPAETAAPLINEFIRDLERLAALLDGKLTE
AAYAEVVGHGEIWSARLMAAVLNQKNLPAAWLDARTFLRAERAAQPQVDEGRSWPLLQQL
LTQNAGQRLVITGFISSNDAGETVLLGRNGSDYSATQIGALAGVERVTIWSDVAGVYSAD
PRKVKDACLLPLLRLDEASELARLAAPVLHARTLQPVSGSDIDLQLRCSYQPEQGSTRIE
RVLASGTGAKIVTSHDDVCLIEIGVPAEHDFARTHKDVEQLLQKSQIRPLALGVHQDRNL
LQLCYTSEVVHSAWQVLEQAALPVSLHLREGLALVALVGAGVCRNPLHSHRFYQQLRDQP
IEFVWQAEDDISLVAVLRVGPTEHLVRGLHHSLFRAEKRIGLVLFGKGNIGSRWLELFAR
EQSLISARTGFEFTLAGVVDSSRSLLDYEGLDASRVLAFFGDEAQERDDDELFLWMRAHP
YDDLVVLDVTASQSVADLYLDFASHGFHVISANKLAGASGGDNYRQIRDAFAKTGRHWLY
NATVGAGLPVNYAVRDLRESGDSILAISGIFSGTLSWLFLQFDGTVPFTELVDQAWQQGL
TEPDPRVDLSGQDVMRKLVILAREAGYEIEPNQVRVESLVPAGCENGSVDQFFEDGEPLN
QQMLQRLEAANEMGLVLRYVARFDVNGKARVGVEAVRADHPLAALLPCDNVFAIESRWYR
DNPLVIRGPGAGRDVTAGAIQSDLNRLAQLL
NT seq 2436 nt   +upstreamnt  +downstreamnt
atgagtgcgttagggatcgcagcggccgtgaaggggcggcaactgcacaaattcggcggc
agcagcctggctgatgtgaaatgttatcagcgtgttgccggcattatggcggattacagc
caggcgggcgatttgatggtggtatcggcggcgggtagcaccaccaaccagttgatcagc
tggttgaacctcagccagtccgaccggatttccgcccatcaggtacaacagtcgctgcgc
cgttatcaaagcgagctgatttccggtttgctgccggctgaaacggcagcgccgcttatc
aatgaattcattcgcgatctggagcgcctcgccgcgttactggatggcaagctcactgag
gcggcctacgccgaagtggtcgggcacggcgaaatctggtccgcccgtctgatggcggcg
gtgctgaatcagaaaaacctgcctgccgcctggctggatgcccgtaccttcctgcgcgcc
gagcgtgcggcgcagccgcaggtcgatgaaggccgctcctggccgctgttgcaacagctg
ttgacccagaatgccgggcaacgtctggtgattaccggttttatcagcagcaatgatgca
ggtgaaaccgtcctgctgggccgtaacggtagcgactattccgccacgcagattggtgcg
ctggctggcgtcgagcgcgttactatctggagtgacgtggccggcgtgtacagcgctgac
ccgcgcaaggtcaaagatgcctgcctgctgccgctgctgcggctggatgaagccagcgaa
ttggcccgtctggcggcgccggtattgcacgcccgtaccctgcagccggtttccggcagc
gatatcgacctgcaattgcgatgcagttatcaacccgaacaagggtcgacccgcattgaa
cgcgtgctggcctccggcaccggcgccaagattgtcaccagtcacgatgacgtttgcctg
attgagattggcgtaccggcggagcacgattttgcccgcactcacaaagacgtcgagcag
ttgctgcaaaaatcccagatccggccgctggcgctgggcgtgcatcaggatcgcaacctg
ctgcagctgtgctacacctcggaagtggtgcacagcgcctggcaggtgctggagcaggcg
gcgttgccggtatcgcttcatctgcgcgaggggcttgcgctggtggcgctggtgggggcg
ggcgtttgccgcaacccgctgcacagtcaccgtttctaccagcaactgcgtgaccagccg
atcgagttcgtctggcaggcggaagacgacatcagcctggtagcggtgctgcgtgtgggg
ccgaccgagcatctggtgcgtggcctgcatcattcgctgttccgggcggaaaaacgcatc
ggcctggtgctattcggcaaaggcaatatcggttcacgctggctggagctgttcgctcgc
gagcagagcctgatttcggcgcgcaccggctttgagttcacgctggcgggcgtggtggac
agttcccgcagcctgctggattacgaggggctggatgccagccgtgtgctggccttcttt
ggcgacgaagcgcaggagcgtgacgacgatgagctgttcctgtggatgcgcgctcatccg
tacgatgatctggtggtgttggatgtcaccgccagccagtcggtcgccgatctctatctg
gatttcgccagccatggtttccatgtgatcagcgccaacaaactggcgggcgcatccggc
ggcgacaactatcgccagatccgcgacgcgttcgctaaaaccgggcgtcactggctgtac
aacgccaccgttggcgccgggttgccggtgaactatgcggtgcgggacctgcgtgaaagc
ggcgacagcattctggctatcagcggtatcttctccggcacgctgtcatggctgttcctg
cagtttgacggaacggtgccttttaccgaactggtggatcaagcctggcagcagggattg
accgagccggatccgcgcgtcgatctttccggtcaggacgtgatgcgcaagctggttatt
ctggcacgcgaagcgggttacgagattgaacccaatcaggtgcgggtggaatcgctggtg
cctgccggatgcgagaacggttcggtggatcaattctttgaagacggcgagccgctgaat
cagcaaatgctgcagcgactggaagccgccaacgagatggggctggtgctgcgctatgtt
gcccgcttcgatgtcaacggcaaggcgcgcgtaggcgtggaagccgtgcgggcggatcat
ccgctggcggcgttgttgccgtgtgataacgtgttcgccatcgaaagtcgctggtaccgc
gataacccgctggtgattcgcggcccgggagccggccgcgacgtaacggccggggcgatt
caatcggatctcaatcggctggcgcaactgctgtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (13)   
   KEGG PATHWAY (8)   
   KEGG MODULE (5)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (39)   

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