KEGG   Desulfitobacterium dehalogenans: Desde_0064
Entry
Desde_0064        CDS       T02146                                 
Name
(GenBank) 5,10-methylenetetrahydrofolate reductase
  KO
K00297  methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54]
Organism
ddh  Desulfitobacterium dehalogenans
Pathway
ddh00670  One carbon pool by folate
ddh00720  Carbon fixation pathways in prokaryotes
ddh01100  Metabolic pathways
ddh01120  Microbial metabolism in diverse environments
ddh01200  Carbon metabolism
Module
ddh_M00377  Reductive acetyl-CoA pathway (Wood-Ljungdahl pathway)
ddh_M00618  Acetogen
Brite
KEGG Orthology (KO) [BR:ddh00001]
 09100 Metabolism
  09102 Energy metabolism
   00720 Carbon fixation pathways in prokaryotes
    Desde_0064
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    Desde_0064
Enzymes [BR:ddh01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.54  methylenetetrahydrofolate reductase (NADH)
     Desde_0064
SSDB
Motif
Pfam: DUF5981 MTHFR
Other DBs
NCBI-ProteinID: AFL98559
UniProt: I4A3M5
Position
complement(63915..65501)
AA seq 528 aa
MENRFKQSLLDPNTLSVTWELVPGRGAREKAQESALLAAEQAAKGGKVHALTITDNPGGN
PAILADYLGQEILKLGIEPLVHFTCKDKNRNQMESQLYALDRAEVRSLLVMTGDYTVSGF
KGRPKPVFDLDPTHALELITQMNQGLGIPGPKGMSYHQTSDFFAGAAVSPFKGTEAEQMV
QYYKLKKKVASGAQFIVTQLGYDVRKIHEVLQFMKLNDLNVPLVGNIYILPFGAAKIMNQ
NQLPGCVVTDKLLAEIDKERTAEDKGVGARLLRAAKMYALMKGMGFAGVHIGGHNIKYEQ
VEYVIEKGEELSKDWMALIPEFDYPMPNGFYYYEKDPKTGLNTTTPVNRKNLPLDAPVGV
AYSGMRMMHSMLFTPGKNFFPVMRKIYKGRKDNRKHGFEHLAKVITNDCKDCGDCAMFEL
AYLCPMSQCPKNQRNGACGGSYQGWCEVYPNQKQCIYVRAYARLKKYSEEGDLDSHHIPP
ANWDLYQTSSWSNFFLGRDHSGEILGIPTPEEEEKAKSVDSTKQDVSK
NT seq 1587 nt   +upstreamnt  +downstreamnt
atggagaaccgttttaaacagtctttattggaccctaacaccctctccgtcacttgggaa
ctggtccctgggagaggagcacgtgagaaagctcaagaaagcgcattgcttgctgcagaa
caggcagctaagggcggtaaggttcatgccctgaccatcaccgataaccccggaggaaac
cctgctattctcgccgattatcttggtcaggagattctcaagctgggaatagagcccctt
gtccattttacctgtaaggataagaaccgcaatcagatggagagccagctttatgctctt
gatcgggcagaagtccgcagcctcttggtaatgaccggagattatacggtctctggcttt
aaaggccgccccaagccggtctttgaccttgatcctacccatgctttagaactcatcacc
caaatgaatcaagggcttggtattcctggccctaagggaatgtcttatcaccaaaccagt
gatttctttgccggtgccgccgtttctccctttaagggcacggaagcagagcaaatggtc
caatattataaactgaagaaaaaagtggccagcggagcccaatttattgtcacccagctt
ggctatgatgtccgtaaaatccatgaagtcctccaattcatgaagcttaatgatctgaat
gttccccttgtaggcaatatctatatcctccccttcggtgcagccaagattatgaaccag
aatcagctgccgggctgtgttgtcacggataagctcctggctgaaattgataaggaaaga
acagccgaggataaaggggtcggtgcccgcttgctgagagccgctaagatgtacgctctc
atgaaaggcatgggctttgccggagttcatatcggcgggcataatatcaaatatgagcaa
gtggaatatgtgattgaaaagggcgaggagctcagcaaagactggatggctctgattcct
gagtttgattatcctatgcccaatggtttctattattatgaaaaggatcccaaaaccggc
ctcaataccaccacacctgtcaatcggaagaacttgcctctggatgcccctgtgggagta
gcttacagcggtatgagaatgatgcacagcatgctcttcacccccggcaaaaacttcttc
cccgtcatgcgcaagatttataaaggacgtaaggataaccgcaaacacggctttgaacac
ctggcaaaagtcatcaccaacgactgtaaggactgcggggactgtgctatgttcgaactg
gcttatctctgtcctatgtctcaatgtcccaagaaccaaaggaacggtgcctgcggcgga
agctatcagggctggtgtgaggtttaccccaaccagaagcagtgtatttatgtcagagct
tatgcccgcttgaagaaatatagtgaggaaggggatctggattctcatcatattcccccg
gccaattgggatttgtatcaaacctcctcatggtctaacttcttcttaggacgggatcac
tctggagaaatcttgggtattcccactcctgaagaagaggagaaggctaagagcgtagat
tcgactaagcaagacgtgtctaaataa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (5)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (2)   
   Pfam (2)   
All databases (22)   

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