KEGG   Delphinapterus leucas (beluga whale): 111180824
Entry
111180824         CDS       T05885                                 
Symbol
TGFB1
Name
(RefSeq) transforming growth factor beta-1 proprotein isoform X1
  KO
K13375  transforming growth factor beta-1
Organism
dle  Delphinapterus leucas (beluga whale)
Pathway
dle04010  MAPK signaling pathway
dle04060  Cytokine-cytokine receptor interaction
dle04068  FoxO signaling pathway
dle04110  Cell cycle
dle04148  Efferocytosis
dle04218  Cellular senescence
dle04350  TGF-beta signaling pathway
dle04380  Osteoclast differentiation
dle04390  Hippo signaling pathway
dle04659  Th17 cell differentiation
dle04672  Intestinal immune network for IgA production
dle04926  Relaxin signaling pathway
dle04932  Non-alcoholic fatty liver disease
dle04933  AGE-RAGE signaling pathway in diabetic complications
dle05140  Leishmaniasis
dle05142  Chagas disease
dle05144  Malaria
dle05145  Toxoplasmosis
dle05146  Amoebiasis
dle05152  Tuberculosis
dle05161  Hepatitis B
dle05166  Human T-cell leukemia virus 1 infection
dle05200  Pathways in cancer
dle05205  Proteoglycans in cancer
dle05210  Colorectal cancer
dle05211  Renal cell carcinoma
dle05212  Pancreatic cancer
dle05220  Chronic myeloid leukemia
dle05225  Hepatocellular carcinoma
dle05226  Gastric cancer
dle05321  Inflammatory bowel disease
dle05323  Rheumatoid arthritis
dle05410  Hypertrophic cardiomyopathy
dle05414  Dilated cardiomyopathy
dle05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:dle00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    111180824 (TGFB1)
   04350 TGF-beta signaling pathway
    111180824 (TGFB1)
   04390 Hippo signaling pathway
    111180824 (TGFB1)
   04068 FoxO signaling pathway
    111180824 (TGFB1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    111180824 (TGFB1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    111180824 (TGFB1)
  09143 Cell growth and death
   04110 Cell cycle
    111180824 (TGFB1)
   04218 Cellular senescence
    111180824 (TGFB1)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    111180824 (TGFB1)
   04672 Intestinal immune network for IgA production
    111180824 (TGFB1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    111180824 (TGFB1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    111180824 (TGFB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    111180824 (TGFB1)
   05205 Proteoglycans in cancer
    111180824 (TGFB1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    111180824 (TGFB1)
   05212 Pancreatic cancer
    111180824 (TGFB1)
   05225 Hepatocellular carcinoma
    111180824 (TGFB1)
   05226 Gastric cancer
    111180824 (TGFB1)
   05220 Chronic myeloid leukemia
    111180824 (TGFB1)
   05211 Renal cell carcinoma
    111180824 (TGFB1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    111180824 (TGFB1)
   05161 Hepatitis B
    111180824 (TGFB1)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    111180824 (TGFB1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    111180824 (TGFB1)
   05144 Malaria
    111180824 (TGFB1)
   05145 Toxoplasmosis
    111180824 (TGFB1)
   05140 Leishmaniasis
    111180824 (TGFB1)
   05142 Chagas disease
    111180824 (TGFB1)
  09163 Immune disease
   05323 Rheumatoid arthritis
    111180824 (TGFB1)
   05321 Inflammatory bowel disease
    111180824 (TGFB1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    111180824 (TGFB1)
   05414 Dilated cardiomyopathy
    111180824 (TGFB1)
   05415 Diabetic cardiomyopathy
    111180824 (TGFB1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    111180824 (TGFB1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    111180824 (TGFB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:dle03110]
    111180824 (TGFB1)
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:dle04052]
    111180824 (TGFB1)
   00536 Glycosaminoglycan binding proteins [BR:dle00536]
    111180824 (TGFB1)
Chaperones and folding catalysts [BR:dle03110]
 Intramolecular chaperones
  Others
   111180824 (TGFB1)
Cytokines and neuropeptides [BR:dle04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   111180824 (TGFB1)
Glycosaminoglycan binding proteins [BR:dle00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   111180824 (TGFB1)
SSDB
Motif
Pfam: TGFb_propeptide TGF_beta
Other DBs
NCBI-GeneID: 111180824
NCBI-ProteinID: XP_022441295
UniProt: A0A2Y9P5D5
Position
Unknown
AA seq 391 aa
MPPSGLRLLPLLLPLLWLLVLPPGRPAAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLA
SPPSQGEVPPGPLPEAVLALYNSTRDRVAGESAEPEPEPEADYYAKEVTRVLMVENSNEI
YGKIKRSPHSMYMLFNTSELREAVPEPVLLSRAELRLLRLKLKVEQHVELYQKYSNDSWR
YLSNRLLAPSDSPEWLSFDVTGVVRQWLTHGEEIEGFRLSAHCSCDSKDNTLQVDINAGF
SSGRRGDLATIHGMNRPFLLLMATPLERAQHLHSPRHRRALDTNYCFSSTEKNCCVRQLY
IDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQ
ALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS
NT seq 1176 nt   +upstreamnt  +downstreamnt
atgccgccctcggggctgcggctgctgccgctgctgctgccgctgctgtggctactagtg
ctgccgcctggccggccggccgccggactgtccacctgcaagaccatcgacatggagctg
gtgaagcgaaagcgcatcgaggccatccgcggccagattctgtccaagcttcggctcgcc
agccccccgagccagggggaggtgccgcccggtccgctgcccgaggccgtactggccctt
tacaacagtacccgtgaccgggtggccggggaaagtgccgaacctgagcctgagccagag
gcggactactacgccaaggaggtcacccgcgtgctaatggtggaaaacagcaacgaaatc
tatgggaaaatcaagcgtagcccacacagcatgtatatgctcttcaacacgtcggagctc
cgggaagcggtgcccgaacctgtgttgctctctcgggcagagctacgcctgctgaggctc
aagttaaaagtggagcagcacgtggagctgtaccagaaatacagcaatgattcctggcgc
tacctcagcaaccggctgctggcccccagcgactcgccggagtggctgtcctttgacgtc
actggagttgtgcggcagtggctgacccacggagaggaaatagagggctttcgcctcagt
gcccactgttcctgtgacagcaaagataacacactccaagtggacattaacgcagggttc
agttccggccgccggggtgacctcgccaccattcatggcatgaaccggcccttcctgctc
ctcatggccaccccgctggagagggcccagcacctgcacagcccccggcaccgccgagcc
ctggacaccaactactgcttcagctctacggaaaagaactgctgcgttcggcagctctac
attgacttccgcaaggacctgggctggaagtggattcacgaacccaagggctaccacgcc
aatttctgcctggggccctgcccctacatctggagcctggacacgcagtacagcaaggtc
ctggccctgtacaaccagcacaacccgggcgcgtcggcggcgccgtgctgcgtgccgcag
gcgctggagccgctgcccatcgtgtactacgtgggccgcaagcccaaggtggagcagctg
tccaacatgatcgtgcgctcctgcaagtgcagctga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (35)   
   KEGG PATHWAY (35)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (4)   
   RefSeq(nuc) (2)   
   GenBank (1)   
   EMBL (1)   
Protein domain (2)   
   Pfam (2)   
All databases (52)   

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